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SLC16A12 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS243447

MBS243447 is an antibody targeting SLC16A12. Also known as Rabbit Polyclonal (IgG) to Human SLC16A12 / MCT12. Reactive in Human, Mouse. Host: Rabbit. More details

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Testing Data View PDF
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Product Overview

Product Name
SLC16A12 / MCT12, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal (IgG) to Human SLC16A12 / MCT12
Product Gene Name
anti-SLC16A12 antibody
Product Synonym Gene Name
MCT12
Product Synonym Names
Anti-SLC16A12 / MCT12 Antibody (aa115-164) IHC-plus; SLC16A12; CJMG; MCT 12; Monocarboxylate transporter 12; MCT12; Human SLC16A12; MCT12
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
MOT12 Antibody detects endogenous levels of total MOT12 protein.
Preparation and Storage
Store at -20 degree C for up to one year.
Molecular Weight
53,075 Da
OMIM
gene 612018
3D Structure
ModBase 3D Structure for Q6ZSM3
Target Species
Human
Immunogen Description
Synthetic peptide from human MOT12 (aa115-164).
Immunogen
SLC16A12 / MCT12 antibody was raised against synthetic peptide from human MOT12 (aa115-164).
Antigen Modification
aa115-164
Applications Tested/Suitable for anti-SLC16A12 antibody
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
Application Notes for anti-SLC16A12 antibody
ELISA (1:20000), IHC-P (1:50 - 1:100, 10 ug/ml)

Immunohistochemistry (IHC) of anti-SLC16A12 antibody

Anti- Anti-SLC16A12 / MCT12 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4 ug/ml.
Rabbit Anti-SLC16A12 Polyclonal Antibody – Cat# MBS243447

Immunohistochemistry (IHC) of anti-SLC16A12 antibody

Anti-SLC16A12 / MCT12 antibody IHC of human skeletal muscle tissue. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue. Staining on the right was blocked with peptide.
Rabbit Anti-SLC16A12 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS243447

Other Notes

Small volumes of anti-SLC16A12 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC16A12. It may not necessarily be applicable to this product.

NCBI GI #
291621700
NCBI GeneID
387700
NCBI Accession #
NP_998771.3
UniProt Primary Accession #
Q6ZSM3
UniProt Secondary Accession #
Q5M9M9; Q5T7J2; Q6ZV76
UniProt Related Accession #
Q6ZSM3
GenBank Nucleotide #
NM_213606.3
NCBI Official Full Name
monocarboxylate transporter 12
NCBI Official Synonym Full Names
solute carrier family 16, member 12
NCBI Official Symbol
SLC16A12
NCBI Official Synonym Symbols
CJMG; MCT12
UniProt Protein Name
Monocarboxylate transporter 12
UniProt Synonym Protein Names
Creatine transporter 2
Protein Family
Monocarboxylate transporter
UniProt Gene Name
SLC16A12
UniProt Synonym Gene Names
MCT 12
UniProt Entry Name
MOT12_HUMAN
NCBI Protein Information
monocarboxylate transporter 12; monocarboxylic acid transporter 12; solute carrier family 16, member 12 (monocarboxylic acid transporter 12)

NCBI Summary for SLC16A12

This gene encodes a transmembrane transporter that likely plays a role in monocarboxylic acid transport. A mutation in this gene has been associated with juvenile cataracts with microcornea and renal glucosuria. [provided by RefSeq, Mar 2010]

UniProt Comments for SLC16A12

SLC16A12: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates. Defects in SLC16A12 are a cause of cataract juvenile with microcornea and glucosuria (CJMG). Renal glucosuria is defined by elevated glucose level in the urine without hyperglycemia and without evidence of morphological renal anomalies. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.

Protein type: Transporter, SLC family; Membrane protein, multi-pass; Transporter; Membrane protein, integral

Chromosomal Location of Human Ortholog: 10q23.31

Cellular Component: integral to plasma membrane

Molecular Function: creatine transporter activity; symporter activity; lactate transmembrane transporter activity

Disease: Cataract, Juvenile, With Microcornea And Glucosuria
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Research Articles on SLC16A12

1. study identified a second creatine transporter monocarboxylate transporter 12 (MCT12), encoded by the cataract and glucosuria associated gene SLC16A12; Rssults show SLC6A8 was predominantly found in brain, heart and muscle, while SLC16A12 was more abundant in kidney and retina. In the lens, the two transcripts were found at comparable levels.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SLC16A12 antibody

 Reference Product  PubMed Publications
 SLC10A6 antibody  >1 publications with SLC16A12 and SLC10A6
 MFSD5 antibody  >1 publications with SLC16A12 and MFSD5
 MFSD6 antibody  >1 publications with SLC16A12 and MFSD6
 SLC15A5 antibody  >1 publications with SLC16A12 and SLC15A5

Diseases associated with anti-SLC16A12 antibody

 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >2 publications with SLC16A12 and Kidney Diseases
 Nervous System Diseases Antibodies  >1 publications with SLC16A12 and Nervous System Diseases
 Colonic Neoplasms Antibodies  >1 publications with SLC16A12 and Colonic Neoplasms
 Hepatitis Antibodies  >1 publications with SLC16A12 and Hepatitis
 Prostatic Neoplasms Antibodies  >1 publications with SLC16A12 and Prostatic Neoplasms
 Inflammation Antibodies  >1 publications with SLC16A12 and Inflammation
 Cataract, Juvenile, With Microcornea And Glucosuria Antibodies  >1 publications with SLC16A12 and Cataract, Juvenile, With Microcornea And Glucosuria

Organs/Tissues associated with anti-SLC16A12 antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >2 publications with SLC16A12 and Muscle
 Kidney Antibodies  >2 publications with SLC16A12 and Kidney
 Heart Antibodies  >1 publications with SLC16A12 and Heart
 Brain Antibodies  >1 publications with SLC16A12 and Brain
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