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ZMYM3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS243453

MBS243453 is an antibody targeting ZMYM3. Also known as Rabbit Polyclonal to Human ZMYM3. Reactive in Human, Mouse. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
ZMYM3, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human ZMYM3
Product Gene Name
Product Synonym Names
Anti-ZMYM3 Antibody (C-Terminus) IHC-plus; ZMYM3; DXS6673E; KIAA0385; MYM; Zinc finger protein 261; ZNF261; Zinc finger MYM-type protein 3; Zinc finger; MYM-type 3; XFIM; ZNF198L2; Human ZMYM3
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
PBS, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human ZMYM3. At least three isoforms of ZMYM3 are known to exist; this antibody will detect all three. ZMYM3 antibody is predicted to not cross-react with other ZMYM protein family members.
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
Molecular Weight
52,485 Da
OMIM
300061
3D Structure
ModBase 3D Structure for Q14202
Target Species
Human
Immunogen Description
A 20 amino acid peptide near the carboxy terminus of human AXIN2
Immunogen Type
Synthetic peptide
Immunogen
ZMYM3 antibody was raised against a 20 amino acid peptide near the carboxy terminus of human AXIN2
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-ZMYM3 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-ZMYM3 antibody
IHC-P (10 ug/ml), WB (1 - 2 ug/ml)

Immunohistochemistry (IHC) of anti-ZMYM3 antibody

Anti-ZMYM3 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-ZMYM3 Polyclonal Antibody – Cat# MBS243453

Immunohistochemistry (IHC) of anti-ZMYM3 antibody

Anti-ZMYM3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-ZMYM3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS243453

Immunofluorescence (IF) of anti-ZMYM3 antibody

Immunofluorescence of ZMYM3 in human brain tissue with ZMYM3 antibody at 20 ug/ml.
Rabbit Anti-ZMYM3 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS243453

Western Blot (WB) of anti-ZMYM3 antibody

Western blot analysis of ZMYM3 in human brain tissue lysate with ZMYM3 antibody at 1 ug/ml.
Rabbit Anti-ZMYM3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS243453

Other Notes

Small volumes of anti-ZMYM3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ZMYM3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
zinc finger MYM-type protein 3 isoform 1
NCBI Official Synonym Full Names
zinc finger, MYM-type 3
NCBI Official Symbol
ZMYM3
NCBI Official Synonym Symbols
MYM; XFIM; ZNF261; DXS6673E; ZNF198L2
UniProt Protein Name
Zinc finger MYM-type protein 3
UniProt Synonym Protein Names
Zinc finger protein 261
UniProt Gene Name
ZMYM3
UniProt Synonym Gene Names
DXS6673E; KIAA0385; ZNF261
UniProt Entry Name
ZMYM3_HUMAN
NCBI Protein Information
zinc finger MYM-type protein 3; zinc finger protein 261

NCBI Summary for ZMYM3

This gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked mental retardation. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2010]
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UniProt Comments for ZMYM3

ZNF261: Plays a role in the regulation of cell morphology and cytoskeletal organization. A chromosomal aberration involving ZMYM3 may be a cause of X-linked mental retardation in Xq13.1. Translocation t(X;13)(q13.1;?). 3 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: Xq13.1

Cellular Component: nucleus

Molecular Function: DNA binding; zinc ion binding

Biological Process: multicellular organismal development; regulation of cell morphogenesis; cytoskeleton organization and biogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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