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GALR3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS243499

GalR3 is a Galanin Receptor that is similar, but distinct from the other galanin receptors, and it mediates the effects of the galanin peptide in a wide variety of tissues. Like GalR1, the signaling mechanism is predominantly through inhibition of adenylate… More details

$650 / 0.05 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
GALR3 / Galanin Receptor 3, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human GALR3 / Galanin Receptor 3
Product Gene Name
Product Synonym Names
Anti-GALR3 / Galanin Receptor 3 Antibody (Cytoplasmic Domain) IHC-plus; GALR3; Gal receptor-3; Galanin r3 receptor; Gal-r3; Galanin receptor 3; Galanin receptor galr3; Galanin receptor subtype 3; Gal3 receptor; GAL3-R; Galanin 2 receptor homolog; Galanin receptor type 3; GALNR3; GALR-3; Human GALR3; Galanin Receptor 3
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gorilla, Human, Rat
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human GALR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
39,573 Da
OMIM
603692
3D Structure
ModBase 3D Structure for O60755
Target Species
Human
Immunogen Description
Synthetic 17 amino acid peptide from 1st cytoplasmic domain of human GALR3. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Monkey (88%); Marmoset, Rat, Elephant, Pig, Bloom alga (82%).
Immunogen Type
Synthetic peptide
Immunogen
GALR3 / Galanin Receptor 3 antibody was raised against synthetic 17 amino acid peptide from 1st cytoplasmic domain of human GALR3. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Monkey (88%); Marmoset, Rat, Elephant, Pig, Bloom alga (82%).
Antigen Modification
Cytoplasmic Domain
Applications Tested/Suitable for anti-GALR3 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-GALR3 antibody
IHC-P (3 - 7 ug/ml)

Immunohistochemistry (IHC) of anti-GALR3 antibody

Anti-GALR3 antibody IHC of rat brain, hippocampus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-GALR3 Polyclonal Antibody – Cat# MBS243499

Other Notes

Small volumes of anti-GALR3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GALR3 purchase

MBS243499 is an antibody targeting GALR3. Also known as Rabbit Polyclonal to Human GALR3 / Galanin Receptor 3. Reactive in Gorilla, Human, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GALR3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
galanin receptor type 3
NCBI Official Synonym Full Names
galanin receptor 3
NCBI Official Symbol
GALR3
UniProt Protein Name
Galanin receptor type 3
Protein Family
UniProt Gene Name
GALR3
UniProt Synonym Gene Names
GALNR3; GAL3-R; GALR-3
UniProt Entry Name
GALR3_HUMAN
NCBI Protein Information
galanin receptor type 3; GAL3-R; GALR-3; galanin receptor, family member 3

NCBI Summary for GALR3

The neuropeptide galanin modulates a variety of physiologic processes including cognition/memory, sensory/pain processing, hormone secretion, and feeding behavior. The human galanin receptors are G protein-coupled receptors that functionally couple to their intracellular effector through distinct signaling pathways. GALR3 is found in many tissues and may be expressed as 1.4-, 2.4-, and 5-kb transcripts [provided by RefSeq, Jul 2008]
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UniProt Comments for GALR3

GALR3: Receptor for the hormone galanin. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: plasma membrane; integral to membrane

Molecular Function: peptide hormone binding; galanin receptor activity

Biological Process: synaptic transmission; learning and/or memory; neuropeptide signaling pathway; negative regulation of adenylate cyclase activity; positive regulation of transcription from RNA polymerase II promoter; feeding behavior; G-protein signaling, adenylate cyclase inhibiting pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GALR3 antibody

Organs/Tissues associated with anti-GALR3 antibody

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