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SOLO Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS243523

MBS243523 is an antibody targeting SOLO. Also known as Rabbit Polyclonal to Human SOLO / SESTD1. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
SOLO / SESTD1, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human SOLO / SESTD1
Product Gene Name
anti-SOLO antibody
Product Synonym Gene Name
SESTD1
Product Synonym Names
Anti-SOLO / SESTD1 Antibody (C-Terminus) IHC-plus; SESTD1; Protein Solo; SEC14 and spectrin domains 1; SOLO; Human SOLO; SESTD1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human SESTD1
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
Molecular Weight
79,348 Da
3D Structure
ModBase 3D Structure for Q86VW0
Target Species
Human
Immunogen Description
A 15 amino acid peptide near the carboxy terminus of human SESTD1.
Immunogen Type
Synthetic peptide
Immunogen
SOLO / SESTD1 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human SESTD1.
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-SOLO antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-SOLO antibody
ELISA, IHC-P (5 ug/ml), WB (1 - 2 ug/ml)
Usage: SESTD1 antibody can be used for detection of SESTD1 by Western blot at 1-2 ug/ml.

Immunohistochemistry (IHC) of anti-SOLO antibody

Anti-SESTD1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-SOLO Polyclonal Antibody – Cat# MBS243523

Immunofluorescence (IF) of anti-SOLO antibody

Immunofluorescence of SESTD1 in Human Brain cells with SESTD1 antibody at 20 ug/ml.
Rabbit Anti-SOLO Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS243523

Western Blot (WB) of anti-SOLO antibody

Western blot analysis of SESTD1 in rat brain tissue lysate with SESTD1 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.
Rabbit Anti-SOLO Polyclonal Antibody, Western Blot (WB) – Cat# MBS243523

Other Notes

Small volumes of anti-SOLO antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SOLO. It may not necessarily be applicable to this product.

NCBI GI #
188528641
NCBI GeneID
91404
NCBI Accession #
NP_835224.3
UniProt Primary Accession #
Q86VW0
UniProt Secondary Accession #
Q53R38; Q53SP3; Q5GM69; Q8N6M1; Q96LQ2
UniProt Related Accession #
Q86VW0
GenBank Nucleotide #
NM_178123.4
NCBI Official Full Name
SEC14 domain and spectrin repeat-containing protein 1
NCBI Official Synonym Full Names
SEC14 and spectrin domains 1
NCBI Official Symbol
SESTD1
NCBI Official Synonym Symbols
SOLO
UniProt Protein Name
SEC14 domain and spectrin repeat-containing protein 1
UniProt Synonym Protein Names
Huntingtin-interacting protein-like protein; Protein Solo
UniProt Gene Name
SESTD1
UniProt Synonym Gene Names
SOLO
UniProt Entry Name
SESD1_HUMAN
NCBI Protein Information
SEC14 domain and spectrin repeat-containing protein 1; protein Solo; huntingtin-interacting protein-like protein

UniProt Comments for SOLO

SESTD1: May act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5. Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids including phosphatidylcholine, phosphatidylserine, and phosphatidylinositol. The binding to PIP2s is calcium dependent. Might be involved in the plasma membrane localization of CTNNB1. Belongs to the SOLO family.

Chromosomal Location of Human Ortholog: 2q31.2

Molecular Function: protein binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylserine binding; phosphatidylinositol-5-phosphate binding; phosphatidylcholine binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol 3-phosphate binding; phosphatidylinositol binding
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Research Articles on SOLO

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SOLO antibody

 Reference Product  PubMed Publications
 TRPC5 antibody  >2 publications with SOLO and TRPC5

Diseases associated with anti-SOLO antibody

 Disease Name  Pubmed Publications
 Neural Tube Defects Antibodies  >1 publications with SOLO and Neural Tube Defects
 Seizures Antibodies  >1 publications with SOLO and Seizures
 Embryo Loss Antibodies  >1 publications with SOLO and Embryo Loss

Organs/Tissues associated with anti-SOLO antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >2 publications with SOLO and Muscle
 Nerve Antibodies  >1 publications with SOLO and Nerve
 Bladder Antibodies  >1 publications with SOLO and Bladder
 Kidney Antibodies  >1 publications with SOLO and Kidney
 Embryonic Tissue Antibodies  >1 publications with SOLO and Embryonic Tissue
 Vascular Antibodies  >1 publications with SOLO and Vascular
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