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NPY4R Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS243536

NPY4R belongs to the Neuropeptide Receptor GPCR Family and may regulate central nervous system, cardiovascular, and gastrointestinal function. More details

$650 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
NPY4R / PPYR1, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human NPY4R / PPYR1
Product Gene Name
anti-NPY4R antibody
Product Synonym Gene Name
PPYR1
Product Synonym Names
Anti-NPY4R / PPYR1 Antibody (C-Terminus) IHC-plus; NPY4R; Neuropeptide Y4 receptor; Neuropeptide Y receptor type 4; PP1; PPYR1; Y4; NPY4-R; Human NPY4R; PPYR1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gibbon, Human
Predicted Reactivity: Gorilla (at least 90% immunogen sequence identity)
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human PPYR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
42,195 Da
OMIM
601790
3D Structure
ModBase 3D Structure for P50391
Target Species
Human
Immunogen Description
Synthetic 17 amino acid peptide from C-terminus of human PPYR1. Percent identity with other species by BLAST analysis: Human, Gibbon (100%); Gorilla, Panda (94%); Monkey, Bovine, Horse, Pig (88%); Bat, Rabbit (82%).
Immunogen Type
Synthetic peptide
Immunogen
NPY4R / PPYR1 antibody was raised against synthetic 17 amino acid peptide from C-terminus of human PPYR1. Percent identity with other species by BLAST analysis: Human, Gibbon (100%); Gorilla, Panda (94%); Monkey, Bovine, Horse, Pig (88%); Bat, Rabbit (82%).
Antigen Modification
C-Terminus

Product Categories/Family for anti-NPY4R antibody

Family: GPCR; Subfamily: Neuropeptide
Applications Tested/Suitable for anti-NPY4R antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-NPY4R antibody
IHC-P (4 - 6 ug/ml)

Immunohistochemistry (IHC) of anti-NPY4R antibody

Anti-PPYR1 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-NPY4R Polyclonal Antibody – Cat# MBS243536

Immunohistochemistry (IHC) of anti-NPY4R antibody

Anti-NPY4R / PPYR1 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-NPY4R Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS243536

Immunohistochemistry (IHC) of anti-NPY4R antibody

Anti-NPY4R / PPYR1 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-NPY4R Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS243536

Immunohistochemistry (IHC) of anti-NPY4R antibody

Anti-NPY4R / PPYR1 antibody IHC of human Lung, Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-NPY4R Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS243536

Other Notes

Small volumes of anti-NPY4R antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NPY4R purchase

MBS243536 is an antibody targeting NPY4R. Also known as Rabbit Polyclonal to Human NPY4R / PPYR1. Reactive in Gibbon, Human
Predicted Reactivity: Gorilla (at least 90% immunogen sequence identity). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NPY4R. It may not necessarily be applicable to this product.

NCBI GI #
157364957
NCBI GeneID
5540
NCBI Accession #
NP_005963.3
UniProt Primary Accession #
P50391
UniProt Secondary Accession #
Q13456; Q5ISU3; Q5T2X9; Q6FH06
UniProt Related Accession #
P50391
GenBank Nucleotide #
NM_005972.4
NCBI Official Full Name
neuropeptide Y receptor type 4
NCBI Official Synonym Full Names
neuropeptide Y receptor Y4
NCBI Official Symbol
NPY4R
NCBI Official Synonym Symbols
Y4; PP1; PPYR1; NPY4-R
UniProt Protein Name
Neuropeptide Y receptor type 4
UniProt Synonym Protein Names
Pancreatic polypeptide receptor 1; PP1
Protein Family
Neuropeptide Y receptor
UniProt Gene Name
NPY4R
UniProt Synonym Gene Names
PPYR1; NPY4-R; PP1
UniProt Entry Name
NPY4R_HUMAN
NCBI Protein Information
neuropeptide Y receptor type 4; pancreatic polypeptide receptor 1

UniProt Comments for NPY4R

NPY4R: Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PP, PP (2-36) and [Ile-31, Gln-34] PP > [Pro-34] PYY > PYY and [Leu-31, Pro-34] NPY > NPY > PYY (3-36) and NPY (2-36) > PP (13- 36) > PP (31-36) > NPY free acid. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR

Chromosomal Location of Human Ortholog: 10q11.2

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; peptide YY receptor activity; pancreatic polypeptide receptor activity; peptide binding

Biological Process: G-protein coupled receptor protein signaling pathway; blood circulation; neuropeptide signaling pathway; digestion; feeding behavior
Show more

Research Articles on NPY4R

1. Pancreatic polypeptide is recognized by two hydrophobic domains of the human Y4 receptor binding pocket.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NPY4R antibody

 Reference Product  PubMed Publications
 NPY1R antibody  >3 publications with NPY4R and NPY1R
 NPY2R antibody  >3 publications with NPY4R and NPY2R
 NPY antibody  >3 publications with NPY4R and NPY
 NPY5R antibody  >2 publications with NPY4R and NPY5R

Pathways associated with anti-NPY4R antibody

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Metabolic Disorders Of Biological Oxidation Enzymes Pathway antibodies  Metabolic Disorders Of Biological Oxidation Enzymes Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram

Organs/Tissues associated with anti-NPY4R antibody

 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >1 publications with NPY4R and Intestine
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