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GPRC5C Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS243654

MBS243654 is an antibody targeting GPRC5C. Also known as Rabbit Polyclonal to Human GPRC5C. Reactive in Gorilla, HumanPredicted Reactivity: Gibbon, Rat, Bovine, Hamster, Horse (at least 90% immunogen sequence identity). Host: Rabbit. GPRC5C is an Orphan-C… More details

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Technical Datasheet View PDF
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Product Overview

Product Name
GPRC5C, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human GPRC5C
Product Gene Name
Product Synonym Names
Anti-GPRC5C Antibody (Extracellular Domain) IHC-plus; GPRC5C; RAIG-3; RAIG3; Human GPRC5C
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gorilla, Human
Predicted Reactivity: Gibbon, Rat, Bovine, Hamster, Horse (at least 90% immunogen sequence identity)
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human GPRC5C. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
49,389 Da
OMIM
605949
3D Structure
ModBase 3D Structure for Q9NQ84
Target Species
Human
Immunogen Description
Synthetic 18 amino acid peptide from 3rd extracellular domain of human GPRC5C. Percent identity with other species by BLAST analysis: Human, Gorilla, Elephant (100%); Gibbon, Rat, Hamster, Dolphin, Bovine, Horse (94%).
Immunogen Type
Synthetic peptide
Immunogen
GPRC5C antibody was raised against synthetic 18 amino acid peptide from 3rd extracellular domain of human GPRC5C. Percent identity with other species by BLAST analysis: Human, Gorilla, Elephant (100%); Gibbon, Rat, Hamster, Dolphin, Bovine, Horse (94%); Monkey, Marmoset, Mouse, Panda, Dog, Rabbit, Opossum (89%); Pig (83%).
Antigen Modification
Extracellular Domain
Applications Tested/Suitable for anti-GPRC5C antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-GPRC5C antibody
IHC-P (36 ug/ml)

Immunohistochemistry (IHC) of anti-GPRC5C antibody

Anti-GPRC5C antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-GPRC5C Polyclonal Antibody – Cat# MBS243654

Immunohistochemistry (IHC) of anti-GPRC5C antibody

Anti-GPRC5C antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-GPRC5C Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS243654

Immunohistochemistry (IHC) of anti-GPRC5C antibody

Anti-GPRC5C antibody IHC of human stomach, muscularis propria. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-GPRC5C Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS243654

Immunohistochemistry (IHC) of anti-GPRC5C antibody

Anti-GPRC5C antibody IHC of human pancreas, carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-GPRC5C Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS243654

Other Notes

Small volumes of anti-GPRC5C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GPRC5C. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
G-protein coupled receptor family C group 5 member C isoform b
NCBI Official Synonym Full Names
G protein-coupled receptor, class C, group 5, member C
NCBI Official Symbol
GPRC5C
NCBI Official Synonym Symbols
RAIG3; RAIG-3
UniProt Protein Name
G-protein coupled receptor family C group 5 member C
UniProt Synonym Protein Names
Retinoic acid-induced gene 3 protein; RAIG-3
UniProt Gene Name
GPRC5C
UniProt Synonym Gene Names
RAIG3; RAIG-3
UniProt Entry Name
GPC5C_HUMAN
NCBI Protein Information
G-protein coupled receptor family C group 5 member C; orphan G-protein coupled receptor; retinoic acid-induced gene 3 protein; retinoic acid responsive gene protein; G protein-coupled receptor, family C, group 5, member C

NCBI Summary for GPRC5C

The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for GPRC5C

GPRC5C: This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways. Belongs to the G-protein coupled receptor 3 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; GPCR, family 3

Chromosomal Location of Human Ortholog: 17q25

Cellular Component: cytoplasmic vesicle membrane; mitochondrion; integral to plasma membrane; receptor complex; vesicle

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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