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UNC5CL Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS243658

MBS243658 is an antibody targeting UNC5CL. Also known as Rabbit Polyclonal (IgG) to Human UNC5CL. Reactive in Chimpanzee, Human. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
UNC5CL, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal (IgG) to Human UNC5CL
Product Gene Name
Product Synonym Names
Anti-UNC5CL Antibody (aa40-70) IHC-plus; UNC5CL; MUXA; ZUD; UNC5C-like protein; Protein unc-5 homolog C-like; Human UNC5CL
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Chimpanzee, Human
Form/Format
PBS, 0.05% BSA, 0.05% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human UNC5CL
Preparation and Storage
Store at 4 degree C for short term applications. For long term storage, aliquot and store at -20 degree C.
Molecular Weight
57,818 Da
3D Structure
ModBase 3D Structure for Q8IV45
Target Species
Human
Immunogen Description
Portions of amino acids 40-70 and 490-518 of human UNC5CL were used as the immunogen.
Immunogen
UNC5CL antibody was raised against portions of amino acids 40-70 and 490-518 of human UNC5CL were used as the immunogen.
Antigen Modification
aa40-70
Applications Tested/Suitable for anti-UNC5CL antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-UNC5CL antibody
IHC-P (5 ug/ml)

Immunohistochemistry (IHC) of anti-UNC5CL antibody

Anti-UNC5CL antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
Rabbit Anti-UNC5CL Polyclonal Antibody – Cat# MBS243658

Other Notes

Small volumes of anti-UNC5CL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for UNC5CL. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
UNC5C-like protein
NCBI Official Synonym Full Names
unc-5 homolog C (C. elegans)-like
NCBI Official Symbol
UNC5CL
NCBI Official Synonym Symbols
ZUD; MUXA
UniProt Protein Name
UNC5C-like protein
UniProt Synonym Protein Names
Protein unc-5 homolog C-like; ZU5 and death domain-containing protein
Protein Family
UniProt Gene Name
UNC5CL
UniProt Synonym Gene Names
ZUD
UniProt Entry Name
UN5CL_HUMAN
NCBI Protein Information
UNC5C-like protein; protein unc-5 homolog C-like; ZU5 and death domain containing

UniProt Comments for UNC5CL

UNC5CL: Inhibits NF-kappa-B-dependent transcription by impairing NF-kappa-B binding to its targets. Belongs to the unc-5 family.

Protein type: Membrane protein, integral; Inhibitor

Chromosomal Location of Human Ortholog: 6p21.1

Cellular Component: membrane; cytoplasm; integral to membrane

Molecular Function: peptidase activity

Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JNK cascade; signal transduction; proteolysis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-UNC5CL antibody

 Reference Product  PubMed Publications
 RELA antibody  >1 publications with UNC5CL and RELA

Pathways associated with anti-UNC5CL antibody

Diseases associated with anti-UNC5CL antibody

Organs/Tissues associated with anti-UNC5CL antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2 publications with UNC5CL and Blood
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