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DPPL1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS243673

MBS243673 is an antibody targeting DPPL1. Also known as Rabbit Polyclonal to Human DPPL1 / PPAPDC1B. Reactive in Human, Mouse. Host: Rabbit. More details

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Product Overview

Product Name
DPPL1 / PPAPDC1B, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human DPPL1 / PPAPDC1B
Product Gene Name
Product Synonym Gene Name
PPAPDC1B
Product Synonym Names
Anti-DPPL1 / PPAPDC1B Antibody (N-Terminus) IHC-plus; PPAPDC1B; HTPAP; DPPL1; Human DPPL1; PPAPDC1B
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
PBS, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human PPAPDC1B
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
Molecular Weight
19,677 Da
OMIM
610626
3D Structure
ModBase 3D Structure for Q8NEB5
Target Species
Human
Immunogen Description
A 14 amino acid peptide near the amino terminus of human PPAPDC1B.
Immunogen Type
Synthetic peptide
Immunogen
DPPL1 / PPAPDC1B antibody was raised against a 14 amino acid peptide near the amino terminus of human PPAPDC1B.
Antigen Modification
N-Terminus
Applications Tested/Suitable for anti-DPPL1 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-DPPL1 antibody
ELISA, IHC-P (5 ug/ml), WB (1 - 2 ug/ml)
Usage: PPAPDC1B antibody can be used for detection of PPAPDC1B by Western blot at 1-2 ug/ml.

Immunohistochemistry (IHC) of anti-DPPL1 antibody

Anti-PPAPDC1B antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-DPPL1 Polyclonal Antibody – Cat# MBS243673

Western Blot (WB) of anti-DPPL1 antibody

Western blot of PPAPDC1B in EL4 cell lysate with PPAPDC1B antibody at (A) 1 and (B) 2 ug/ml.
Rabbit Anti-DPPL1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS243673

Other Notes

Small volumes of anti-DPPL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DPPL1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
phosphatidate phosphatase PPAPDC1B isoform 1
NCBI Official Synonym Full Names
phosphatidic acid phosphatase type 2 domain containing 1B
NCBI Official Symbol
PPAPDC1B
NCBI Official Synonym Symbols
DPPL1; HTPAP
UniProt Protein Name
Phosphatidate phosphatase PPAPDC1B
UniProt Synonym Protein Names
Phosphatidic acid phosphatase type 2 domain-containing protein 1B
UniProt Gene Name
PPAPDC1B
UniProt Synonym Gene Names
DPPL1; HTPAP
UniProt Entry Name
PPC1B_HUMAN
NCBI Protein Information
phosphatidate phosphatase PPAPDC1B; diacylglycerol pyrophosphate like 1; phosphatidic acid phosphatase type 2 domain-containing protein 1B

UniProt Comments for DPPL1

PPAPDC1B: Displays magnesium-independent phosphatidate phosphatase activity in vitro. Catalyzes the conversion of phosphatidic acid to diacylglycerol. May be a metastatic suppressor for hepatocellular carcinoma. Belongs to the PA-phosphatase related phosphoesterase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; EC 3.1.3.4; Hydrolase; Membrane protein, integral; Tumor suppressor

Chromosomal Location of Human Ortholog: 8p11.23

Cellular Component: cytoplasm; integral to membrane; plasma membrane

Molecular Function: phosphatidate phosphatase activity

Biological Process: phospholipid dephosphorylation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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