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WNT8B Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS243830

WNT genes encode intercellular signaling glycoproteins that play important roles in key processes of embryonic development. WNT8 expression has been seen in several cancers. Recently, WNT8B has been implicated in gastric cancer. More details

$630 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
WNT8B / Wnt 8b, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human WNT8B / Wnt 8b
Product Gene Name
Product Synonym Gene Name
Wnt 8b
Product Synonym Names
Anti-WNT8B / Wnt 8b Antibody (C-Terminus) IHC-plus; WNT8B; Protein Wnt-8b; WNT 8b; Human WNT8B; Wnt 8b
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gibbon, Gorilla, Human
Predicted Reactivity: Monkey, Bat, Dog, Horse, Rabbit (at least 90% immunogen sequence identity)
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human WNT8B. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
38,721 Da
OMIM
601396
3D Structure
ModBase 3D Structure for Q93098
Target Species
Human
Immunogen Description
Synthetic 17 amino acid peptide from C-Terminus of human WNT8B. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Panda (100%); Marmoset, Dog, Bat, Horse, Rabbit (94%); Bovine (88%); Elephant (82%).
Immunogen Type
Synthetic peptide
Immunogen
WNT8B / Wnt 8b antibody was raised against synthetic 17 amino acid peptide from C-Terminus of human WNT8B. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Panda (100%); Marmoset, Dog, Bat, Horse, Rabbit (94%); Bovine (88%); Elephant (82%).
Antigen Modification
C-Terminus

Product Categories/Family for anti-WNT8B antibody

Applications Tested/Suitable for anti-WNT8B antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-WNT8B antibody
IHC-P (10 - 20 ug/ml)

Immunohistochemistry (IHC) of anti-WNT8B antibody

Anti-WNT8B antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-WNT8B Polyclonal Antibody – Cat# MBS243830

Other Notes

Small volumes of anti-WNT8B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for WNT8B purchase

MBS243830 is an antibody targeting WNT8B. Also known as Rabbit Polyclonal to Human WNT8B / Wnt 8b. Reactive in Gibbon, Gorilla, Human
Predicted Reactivity: Monkey, Bat, Dog, Horse, Rabbit (at least 90% immunogen sequence identity). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for WNT8B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein Wnt-8b
NCBI Official Synonym Full Names
wingless-type MMTV integration site family, member 8B
NCBI Official Symbol
WNT8B
UniProt Protein Name
Protein Wnt-8b
Protein Family
UniProt Gene Name
WNT8B
UniProt Entry Name
WNT8B_HUMAN
NCBI Protein Information
protein Wnt-8b

NCBI Summary for WNT8B

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 95%, 86% and 71% amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy. [provided by RefSeq, Jul 2008]
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UniProt Comments for WNT8B

WNT8B: Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role in the development and differentiation of certain forebrain structures, notably the hippocampus. Belongs to the Wnt family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 10q24

Cellular Component: extracellular space; proteinaceous extracellular matrix; extracellular region

Molecular Function: frizzled binding

Biological Process: neuron differentiation; nervous system development; Wnt receptor signaling pathway; response to retinoic acid; cell fate commitment; gastrulation; determination of dorsal identity; signal transduction; response to estradiol stimulus
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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