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CNTROB Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS243991

MBS243991 is an antibody targeting CNTROB. Also known as Rabbit Polyclonal (IgG) to Human CNTROB. Reactive in Human. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CNTROB, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal (IgG) to Human CNTROB
Product Gene Name
Product Synonym Names
Anti-CNTROB Antibody (aa591-640) IHC-plus; CNTROB; Centrobin; LYST-interacting protein 8; LYST-interacting protein LIP8; LIP8; PP1221; Human CNTROB
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
CNTROB Antibody detects endogenous levels of total CNTROB protein.
Preparation and Storage
Store at -20 degree C for up to one year.
Molecular Weight
97,113 Da
OMIM
611425
3D Structure
ModBase 3D Structure for Q8N137
Target Species
Human
Immunogen Description
Synthetic peptide from human CNTROB (aa591-640).
Immunogen
CNTROB antibody was raised against synthetic peptide from human CNTROB (aa591-640).
Antigen Modification
aa591-640
Applications Tested/Suitable for anti-CNTROB antibody
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
Application Notes for anti-CNTROB antibody
ELISA (1:5000), IHC-P (10 ug/ml)

Immunohistochemistry (IHC) of anti-CNTROB antibody

Anti-CNTROB antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.
Rabbit Anti-CNTROB Polyclonal Antibody – Cat# MBS243991

Other Notes

Small volumes of anti-CNTROB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CNTROB. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
centrobin isoform beta
NCBI Official Synonym Full Names
centrobin, centrosomal BRCA2 interacting protein
NCBI Official Symbol
CNTROB
NCBI Official Synonym Symbols
LIP8; PP1221
UniProt Protein Name
Centrobin
UniProt Synonym Protein Names
Centrosomal BRCA2-interacting protein; LYST-interacting protein 8
Protein Family
UniProt Gene Name
CNTROB
UniProt Synonym Gene Names
LIP8
UniProt Entry Name
CNTRB_HUMAN
NCBI Protein Information
centrobin; LYST-interacting protein 8; LYST-interacting protein LIP8; centrosomal BRCA2-interacting protein

NCBI Summary for CNTROB

This gene encodes a centrosomal protein that interacts with BRCA2, and is required for centriole duplication and cytokinesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

UniProt Comments for CNTROB

LIP8: Required for centriole duplication. Inhibition of centriole duplication leading to defects in cytokinesis. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: centriole; centrosome; cytoplasm

Molecular Function: protein domain specific binding; protein binding

Biological Process: centrosome separation; centriole replication
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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