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SLC39A7 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS244052

MBS244052 is an antibody targeting SLC39A7. Also known as Rabbit Polyclonal to Human SLC39A7 / ZIP7. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Overview

Product Name
SLC39A7 / ZIP7, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human SLC39A7 / ZIP7
Product Gene Name
anti-SLC39A7 antibody
Product Synonym Gene Name
ZIP7
Product Synonym Names
Anti-SLC39A7 / ZIP7 Antibody (N-Terminus) IHC-plus; SLC39A7; D6S115E; H2-KE4; HKE4; RING5; Zinc transporter SLC39A7; ZIP7; D6S2244E; KE4; Human SLC39A7; ZIP7
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human SLC39A7
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
Molecular Weight
50,118 Da
OMIM
601416
3D Structure
ModBase 3D Structure for Q92504
Target Species
Human
Immunogen Description
A 17 amino acid peptide near the amino terminus of human ZIP7.
Immunogen Type
Synthetic peptide
Immunogen
SLC39A7 / ZIP7 antibody was raised against a 17 amino acid peptide near the amino terminus of human ZIP7.
Antigen Modification
N-Terminus

Product Categories/Family for anti-SLC39A7 antibody

Family: Transporter; Subfamily: Zinc-iron transporter
Applications Tested/Suitable for anti-SLC39A7 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-SLC39A7 antibody
ELISA, IHC-P (5 ug/ml), WB (0.5 - 1 ug/ml)
Usage: ZIP7 antibody can be used for detection of ZIP7 by Western blot at 0.5-1 ug/ml.

Immunohistochemistry (IHC) of anti-SLC39A7 antibody

Anti-SLC39A7 antibody IHC of human colon, myenteric plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-SLC39A7 Polyclonal Antibody – Cat# MBS244052

Immunohistochemistry (IHC) of anti-SLC39A7 antibody

Anti-SLC39A7 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-SLC39A7 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS244052

Immunofluorescence (IF) of anti-SLC39A7 antibody

Immunofluorescence of ZIP7 in human brain tissue with ZIP7 antibody at 20 ug/ml.
Rabbit Anti-SLC39A7 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS244052

Western Blot (WB) of anti-SLC39A7 antibody

Western blot analysis of ZIP7 in mouse brain tissue lysate with ZIP7 antibody at (A) 0.5 and (B) 1 ug/ml.
Rabbit Anti-SLC39A7 Polyclonal Antibody, Western Blot (WB) – Cat# MBS244052

Other Notes

Small volumes of anti-SLC39A7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC39A7. It may not necessarily be applicable to this product.

NCBI GI #
117553608
NCBI GeneID
7922
NCBI Accession #
NP_008910.2
UniProt Primary Accession #
Q92504
UniProt Secondary Accession #
Q5STP8; Q9UIQ0; B0UXF6
UniProt Related Accession #
Q92504
GenBank Nucleotide #
NM_006979.2
NCBI Official Full Name
zinc transporter SLC39A7 isoform 1
NCBI Official Synonym Full Names
solute carrier family 39 (zinc transporter), member 7
NCBI Official Symbol
SLC39A7
NCBI Official Synonym Symbols
KE4; HKE4; ZIP7; RING5; H2-KE4; D6S115E; D6S2244E
UniProt Protein Name
Zinc transporter SLC39A7
UniProt Synonym Protein Names
Histidine-rich membrane protein Ke4; Really interesting new gene 5 protein; Solute carrier family 39 member 7; Zrt-, Irt-like protein 7; ZIP7
Protein Family
Zinc transporter
UniProt Gene Name
SLC39A7
UniProt Synonym Gene Names
HKE4; RING5; ZIP7
UniProt Entry Name
S39A7_HUMAN
NCBI Protein Information
zinc transporter SLC39A7; zrt-, Irt-like protein 7; Ke4 gene, mouse, human homolog of; solute carrier family 39 member 7; histidine-rich membrane protein Ke4; really interesting new gene 5 protein; HLA class II region expressed gene KE4

NCBI Summary for SLC39A7

The protein encoded by this gene transports zinc from the Golgi and endoplasmic reticulum to the cytoplasm. This transport may be important for activation of tyrosine kinases, some of which could be involved in cancer progression. Therefore, modulation of the encoded protein could be useful as a therapeutic agent against cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
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UniProt Comments for SLC39A7

SLC39A7: transports zinc from the Golgi and endoplasmic reticulum to the cytoplasm. This transport may be important for activation of tyrosine kinases, some of which could be involved in cancer progression. Therefore, modulation of the encoded protein could be useful as a therapeutic agent against cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2011]

Protein type: Transporter, SLC family; Transporter; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: nucleoplasm; Golgi apparatus; endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to membrane

Molecular Function: protein binding; metal ion transmembrane transporter activity

Biological Process: zinc ion transport; transmembrane transport
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Research Articles on SLC39A7

1. The connection with proliferation and migration, as well as the activation of ZIP7 by CK2, a kinase that is antiapoptotic and promotes cell division

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SLC39A7 antibody

 Reference Product  PubMed Publications
 SLC30A5 antibody  >2 publications with SLC39A7 and SLC30A5

Pathways associated with anti-SLC39A7 antibody

 Products by Pathway  Pathway Diagram
 Metal Ion SLC Transporters Pathway antibodies  Metal Ion SLC Transporters Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway antibodies  Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway Diagram
 Zinc Influx Into Cells By The SLC39 Gene Family Pathway antibodies  Zinc Influx Into Cells By The SLC39 Gene Family Pathway Diagram
 Zinc Transporters Pathway antibodies  Zinc Transporters Pathway Diagram

Diseases associated with anti-SLC39A7 antibody

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >3 publications with SLC39A7 and Breast Neoplasms
 Nervous System Diseases Antibodies  >1 publications with SLC39A7 and Nervous System Diseases

Organs/Tissues associated with anti-SLC39A7 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >3 publications with SLC39A7 and Liver
 Intestine Antibodies  >3 publications with SLC39A7 and Intestine
 Brain Antibodies  >3 publications with SLC39A7 and Brain
 Kidney Antibodies  >2 publications with SLC39A7 and Kidney
 Muscle Antibodies  >2 publications with SLC39A7 and Muscle
 Pancreas Antibodies  >2 publications with SLC39A7 and Pancreas
 Lung Antibodies  >1 publications with SLC39A7 and Lung
 Eye Antibodies  >1 publications with SLC39A7 and Eye
 Ovary Antibodies  >1 publications with SLC39A7 and Ovary
 Connective Tissue Antibodies  >1 publications with SLC39A7 and Connective Tissue
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