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GPR6 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS244065

GPR6 has been identified as a constitutively active lysophospholipid/lysosphingolipid receptor. More details

$650 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GPR6, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human GPR6
Product Gene Name
Product Synonym Names
Anti-GPR6 Antibody (Cytoplasmic Domain) IHC-plus; GPR6; G protein-coupled receptor 6; G-protein coupled receptor 6; RCNL3; Human GPR6
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Bat, Gibbon, Bovine, Dog, Gorilla, Hamster, Human, Monkey, Mouse, Pig, Rabbit, Rat
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human GPR6. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GPR12 (60%).
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
39,439 Da
OMIM
600553
3D Structure
ModBase 3D Structure for P46095
Target Species
Human
Immunogen Description
Synthetic 15 amino acid peptide from 3rd cytoplasmic domain of human GPR6. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Bat, Hamster, Elephant, Rabbit, Pig (100%); Opossum (80%).
Immunogen Type
Synthetic peptide
Immunogen
GPR6 antibody was raised against synthetic 15 amino acid peptide from 3rd cytoplasmic domain of human GPR6. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Bat, Hamster, Elephant, Rabbit, Pig (100%); Opossum (80%).
Antigen Modification
Cytoplasmic Domain
Applications Tested/Suitable for anti-GPR6 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-GPR6 antibody
IHC-P (6 - 9 ug/ml)

Immunohistochemistry (IHC) of anti-GPR6 antibody

Anti-GPR6 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-GPR6 Polyclonal Antibody – Cat# MBS244065

Immunohistochemistry (IHC) of anti-GPR6 antibody

Anti-GPR6 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-GPR6 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS244065

Other Notes

Small volumes of anti-GPR6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GPR6 purchase

MBS244065 is an antibody targeting GPR6. Also known as Rabbit Polyclonal to Human GPR6. Reactive in Bat, Gibbon, Bovine, Dog, Gorilla, Hamster, Human, Monkey, Mouse, Pig, Rabbit, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GPR6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
G-protein coupled receptor 6 isoform b
NCBI Official Synonym Full Names
G protein-coupled receptor 6
NCBI Official Symbol
GPR6
UniProt Protein Name
G-protein coupled receptor 6
UniProt Synonym Protein Names
Sphingosine 1-phosphate receptor GPR6
UniProt Gene Name
GPR6
UniProt Entry Name
GPR6_HUMAN
NCBI Protein Information
G-protein coupled receptor 6; sphingosine 1-phosphate receptor GPR6

UniProt Comments for GPR6

GPR6: Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and blocks myelin inhibition in neurons. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 6q21

Cellular Component: integral to plasma membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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