• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

HTR1E Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS244106

5HT1E, a Serotonin Receptor, is not well studied. It is classified as an 5-HT1-like receptor because of its ligand-binding and effector-coupling characteristics. The human 5-HT1E receptor has been studied in an African green monkey kidney cell line, in which… More details

$630 / 0.05 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HTR1E / 5-HT1E Receptor, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human HTR1E / 5-HT1E Receptor
Product Gene Name
anti-HTR1E antibody
Product Synonym Names
Anti-HTR1E / 5-HT1E Receptor Antibody (Cytoplasmic Domain) IHC-plus; HTR1E; 5-HT1E; 5-HT1e receptor; 5-HT-1E; 5HT1E Receptor; HT1e receptor; S31; Serotonin 5-HT-1e receptor; Serotonin 1e receptor; Serotonin receptor 1E; Human HTR1E; 5-HT1E Receptor
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gibbon, Bovine, Chimpanzee, Chicken, Guinea pig, Gorilla, Horse, Human, Monkey, Orangutan
Predicted Reactivity: Bat (at least 90% immunogen sequence identity)
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human 5HT1E Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except HTR1F (65%).
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
41,682 Da
OMIM
182132
3D Structure
ModBase 3D Structure for P28566
Target Species
Human
Immunogen Description
Synthetic 17 amino acid peptide from 3rd cytoplasmic domain of human 5HT1E Receptor.
Immunogen Type
Synthetic peptide
Immunogen
HTR1E / 5-HT1E Receptor antibody was raised against synthetic 17 amino acid peptide from 3rd cytoplasmic domain of human 5HT1E Receptor. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Elephant, Panda, Bovine, Horse, Guinea pig, Turkey, Sparrow, Chicken, Lizard (100%); Bat, Opossum (94%); Stickleback, Zebrafish (88%).
Antigen Modification
Cytoplasmic Domain

Product Categories/Family for anti-HTR1E antibody

Family: GPCR; Subfamily: Serotonin
Applications Tested/Suitable for anti-HTR1E antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-HTR1E antibody
IHC-P (10 ug/ml)
Usage: Antigen retrieval requires Proteinase K treatment.

Immunohistochemistry (IHC) of anti-HTR1E antibody

Anti-5HT1E Receptor antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-HTR1E Polyclonal Antibody – Cat# MBS244106

Immunohistochemistry (IHC) of anti-HTR1E antibody

Anti-5HT1E Receptor antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-HTR1E Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS244106

Other Notes

Small volumes of anti-HTR1E antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HTR1E purchase

MBS244106 is an antibody targeting HTR1E. Also known as Rabbit Polyclonal to Human HTR1E / 5-HT1E Receptor. Reactive in Gibbon, Bovine, Chimpanzee, Chicken, Guinea pig, Gorilla, Horse, Human, Monkey, Orangutan
Predicted Reactivity: Bat (at least 90% immunogen sequence identity). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HTR1E. It may not necessarily be applicable to this product.

NCBI GI #
4504537
NCBI GeneID
3354
NCBI Accession #
NP_000856.1
UniProt Primary Accession #
P28566
UniProt Secondary Accession #
Q9P1Y1; E1P503
UniProt Related Accession #
P28566
GenBank Nucleotide #
NM_000865.2
NCBI Official Full Name
5-hydroxytryptamine receptor 1E
NCBI Official Synonym Full Names
5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
NCBI Official Symbol
HTR1E
NCBI Official Synonym Symbols
5-HT1E
UniProt Protein Name
5-hydroxytryptamine receptor 1E
UniProt Synonym Protein Names
S31; Serotonin receptor 1E
Protein Family
5-hydroxytryptamine receptor
UniProt Gene Name
HTR1E
UniProt Synonym Gene Names
5-HT-1E; 5-HT1E
UniProt Entry Name
5HT1E_HUMAN
NCBI Protein Information
5-hydroxytryptamine receptor 1E; S31; 5-HT-1E; serotonin receptor 1E

UniProt Comments for HTR1E

5-HT(1E): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1

Chromosomal Location of Human Ortholog: 6q14-q15

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; serotonin binding; serotonin receptor activity

Biological Process: synaptic transmission; G-protein signaling, coupled to cyclic nucleotide second messenger; G-protein coupled receptor protein signaling pathway; negative regulation of cAMP metabolic process; G-protein signaling, adenylate cyclase inhibiting pathway; serotonin receptor signaling pathway
Show more

Research Articles on HTR1E

1. Clinical trial of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-HTR1E antibody

 Reference Product  PubMed Publications
 HTR1B antibody  >4 publications with HTR1E and HTR1B
 HTR1A antibody  >3 publications with HTR1E and HTR1A
 HTR1F antibody  >2 publications with HTR1E and HTR1F
 HTR1D antibody  >1 publications with HTR1E and HTR1D
 GAL antibody  >1 publications with HTR1E and GAL

Pathways associated with anti-HTR1E antibody

 Products by Pathway  Pathway Diagram
 Amine Ligand-binding Receptors Pathway antibodies  Amine Ligand-binding Receptors Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Metabolic Disorders Of Biological Oxidation Enzymes Pathway antibodies  Metabolic Disorders Of Biological Oxidation Enzymes Pathway Diagram
 Monoamine GPCRs Pathway antibodies  Monoamine GPCRs Pathway Diagram
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000