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TRIM39 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS244183

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified.… More details

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Product Overview

Product Name
TRIM39 / RNF23, Polyclonal Antibody
Full Product Name
Goat Polyclonal to Human TRIM39 / RNF23
Product Gene Name
Product Synonym Gene Name
RNF23
Product Synonym Names
Anti-TRIM39 / RNF23 Antibody (C-Terminus) IHC-plus; TRIM39; Tripartite motif containing 39; Testis-abundant finger protein; TRIM39B; RING finger protein 23; RNF23; Tripartite motif-containing 39; TFP; Human TRIM39; RNF23
Clonality
Polyclonal
Host
Goat
Species Reactivity
Gibbon, Chimpanzee, Dog, Gorilla, Hamster, Human, Monkey, Mouse, Orangutan, Rabbit, Rat
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human TRIM39 / RNF23. This antibody is expected to recognise both reported isoforms (NP_067076.2 and NP_742013.1).
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Molecular Weight
56,374 Da
OMIM
605700
3D Structure
ModBase 3D Structure for Q9HCM9
Target Species
Human
Immunogen Description
Synthetic peptide C-NAAPLTIRPPTDWE from the C-terminus of human TRIM39 / RNF23 (NP_067076.2; NP_742013.1).
Immunogen Type
Synthetic peptide
Immunogen
TRIM39 / RNF23 antibody was raised against synthetic peptide C-NAAPLTIRPPTDWE from the C-terminus of human TRIM39 / RNF23 (NP_067076.2; NP_742013.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Rabbit, Opossum (100%).
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-TRIM39 antibody
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
Application Notes for anti-TRIM39 antibody
ELISA (1:32000), IHC-P (3.75 ug/ml)

Immunohistochemistry (IHC) of anti-TRIM39 antibody

Anti-TRIM39 / RNF23 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Goat Anti-TRIM39 Polyclonal Antibody – Cat# MBS244183

Other Notes

Small volumes of anti-TRIM39 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TRIM39 purchase

MBS244183 is an antibody targeting TRIM39. Also known as Goat Polyclonal to Human TRIM39 / RNF23. Reactive in Gibbon, Chimpanzee, Dog, Gorilla, Hamster, Human, Monkey, Mouse, Orangutan, Rabbit, Rat. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for TRIM39. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
E3 ubiquitin-protein ligase TRIM39 isoform 1
NCBI Official Synonym Full Names
tripartite motif containing 39
NCBI Official Symbol
TRIM39
NCBI Official Synonym Symbols
TFP; RNF23; TRIM39B
UniProt Protein Name
E3 ubiquitin-protein ligase TRIM39
UniProt Synonym Protein Names
RING finger protein 23; Testis-abundant finger protein; Tripartite motif-containing protein 39
UniProt Gene Name
TRIM39
UniProt Synonym Gene Names
RNF23; TFP
UniProt Entry Name
TRI39_HUMAN
NCBI Protein Information
E3 ubiquitin-protein ligase TRIM39; ring finger protein 23; testis-abundant finger protein; tripartite motif-containing 39; tripartite motif-containing protein 39

UniProt Comments for TRIM39

TRIM39: E3 ubiquitin-protein ligase. May facilitate apoptosis by inhibiting APC/C-Cdh1-mediated poly-ubiquitination and subsequent proteasome-mediated degradation of the pro-apoptotic protein MOAP1. Belongs to the TRIM/RBCC family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: mitochondrion; cytosol

Molecular Function: identical protein binding; protein binding; zinc ion binding; ligase activity

Biological Process: apoptosis; protein ubiquitination
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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