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CAMK4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS244224

CAMK4 belongs to the CAMK1 subfamily of Serine/Threonine Kinases. CAMK4 has been implicated in long term memory, regulation of CRE dependent transcription, and in the control of mitochondrial biogenesis in skeletal muscle. Alternative splicing of CAMK4… More details

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Product Overview

Product Name
CAMK4, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal (IgG) to Human CAMK4
Product Gene Name
Product Synonym Names
Anti-CAMK4 Antibody (aa166-215) IHC-plus; CAMK4; CAM kinase IV; CaMK IV; CaMK-GR; CAMKIV; CaMK; CAM kinase- GR; CaM kinase-GR; CaM-KIV; Human CAMK4
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
CaMK4 Antibody detects endogenous levels of total CaMK4 protein.
Preparation and Storage
Long term: -20 degree C; Short term: +4 degree C; Avoid freeze-thaw cycles.
Molecular Weight
51,926 Da
OMIM
114080
3D Structure
ModBase 3D Structure for Q16566
Target Species
Human
Immunogen Description
Synthetic peptide from human CaMK4 (aa166-215).
Immunogen
CAMK4 antibody was raised against synthetic peptide from human CaMK4 (aa166-215).
Antigen Modification
aa166-215
Applications Tested/Suitable for anti-CAMK4 antibody
Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
Application Notes for anti-CAMK4 antibody
ELISA (1:1000), IF (1:100 - 1:500), IHC-P (10 ug/ml), WB (1:500 - 1:1000)

Immunohistochemistry (IHC) of anti-CAMK4 antibody

Anti-CAMK4 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-CAMK4 Polyclonal Antibody – Cat# MBS244224

Immunofluorescence (IF) of anti-CAMK4 antibody

Immunofluorescence of HepG2 cells, using CaMK4 Antibody. The picture on the right is treated with the synthesized peptide.
Rabbit Anti-CAMK4 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS244224

Western Blot (WB) of anti-CAMK4 antibody

Western blot of extracts from K562 cells, treated with H2O2 100 uM 30', using CaMK4 Antibody. The lane on the right is treated with the synthesized peptide.
Rabbit Anti-CAMK4 Polyclonal Antibody, Western Blot (WB) – Cat# MBS244224

Other Notes

Small volumes of anti-CAMK4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CAMK4 purchase

MBS244224 is an antibody targeting CAMK4. Also known as Rabbit Polyclonal (IgG) to Human CAMK4. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CAMK4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
calcium/calmodulin-dependent protein kinase type IV
NCBI Official Synonym Full Names
calcium/calmodulin-dependent protein kinase IV
NCBI Official Symbol
CAMK4
NCBI Official Synonym Symbols
IV; caMK; CaMK IV; CaMK-GR
UniProt Protein Name
Calcium/calmodulin-dependent protein kinase type IV
UniProt Synonym Protein Names
CaM kinase-GR
UniProt Gene Name
CAMK4
UniProt Synonym Gene Names
CAMK; CAMK-GR; CAMKIV; CaMK IV
UniProt Entry Name
KCC4_HUMAN
NCBI Protein Information
calcium/calmodulin-dependent protein kinase type IV; CAM kinase IV; caM kinase-GR; CAM kinase- GR; brain Ca++-calmodulin-dependent protein kinase type IV; brain Ca(2+)-calmodulin-dependent protein kinase type IV; calcium/calmodulin-dependent protein kinase type IV catalytic chain

NCBI Summary for CAMK4

The product of this gene belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. [provided by RefSeq, Jul 2008]
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UniProt Comments for CAMK4

CAMK4: a protein kinase of the CAMK1 family. Implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. Two alternatively sliced isoforms have been described.

Protein type: EC 2.7.11.17; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; CAMK group; CAMK1 family

Chromosomal Location of Human Ortholog: 5q21.3

Cellular Component: nucleoplasm; nucleolus; cytosol

Molecular Function: calmodulin binding; calmodulin-dependent protein kinase activity; ATP binding

Biological Process: epidermal growth factor receptor signaling pathway; mitochondrion organization and biogenesis; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; regulation of T cell differentiation in the thymus; organelle organization and biogenesis; positive regulation of transcription, DNA-dependent; myeloid dendritic cell differentiation; nucleocytoplasmic transport; signal transduction; protein amino acid phosphorylation; positive regulation of protein export from nucleus; synaptic transmission; regulation of osteoclast differentiation; long-term memory; phospholipase C activation; innate immune response; nerve-nerve synaptic transmission; inflammatory response; myeloid dendritic cell cytokine production
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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