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LTB4R2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS244286

BLTR2 is a Chemoattractant Receptor that causes LTB4-induced chemotaxis, calcium mobilization, and inhibition of adenylyl cyclase. Portions of the coding regions of BLTR2 have been duplicated and are part of the 5' UTR noncoding regions of the clusters… More details

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Product Overview

Product Name
LTB4R2 / BLT2, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human LTB4R2 / BLT2
Product Gene Name
anti-LTB4R2 antibody
Product Synonym Gene Name
BLT2
Product Synonym Names
Anti-LTB4R2 / BLT2 Antibody (Cytoplasmic Domain) IHC-plus; LTB4R2; BLT2; BLTR2; Blt-2; BLT2R; JULF2; LTB4-R2; Hblt2; KPG_004; Leukotriene B4 receptor 2; Leukotriene B4 receptor BLT2; LTB4 receptor JULF2; LTB4-R 2; Human LTB4R2; BLT2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gorilla, Human, Monkey
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human LTB4R2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
37,942 Da
OMIM
605773
3D Structure
ModBase 3D Structure for Q9NPC1
Target Species
Human
Immunogen Description
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human LTB4R2. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset (100%); Mouse, Rat, Bat (88%); Elephant (81%).
Immunogen Type
Synthetic peptide
Immunogen
LTB4R2 / BLT2 antibody was raised against synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human LTB4R2. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset (100%); Mouse, Rat, Bat (88%); Elephant (81%).
Antigen Modification
Cytoplasmic Domain

Product Categories/Family for anti-LTB4R2 antibody

Family: GPCR; Subfamily: Chemoattractant
Applications Tested/Suitable for anti-LTB4R2 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-LTB4R2 antibody
IHC-P (26 ug/ml)

Immunohistochemistry (IHC) of anti-LTB4R2 antibody

Anti-LTB4R2 / BLT2 antibody IHC of human Colon, Carcinoma and Leukocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-LTB4R2 Polyclonal Antibody – Cat# MBS244286

Immunohistochemistry (IHC) of anti-LTB4R2 antibody

Anti-LTB4R2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-LTB4R2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS244286

Immunohistochemistry (IHC) of anti-LTB4R2 antibody

Anti-LTB4R2 / BLT2 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-LTB4R2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS244286

Other Notes

Small volumes of anti-LTB4R2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LTB4R2 purchase

MBS244286 is an antibody targeting LTB4R2. Also known as Rabbit Polyclonal to Human LTB4R2 / BLT2. Reactive in Gorilla, Human, Monkey. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LTB4R2. It may not necessarily be applicable to this product.

NCBI GI #
291042665
NCBI GeneID
56413
NCBI Accession #
NP_062813.2
UniProt Primary Accession #
Q9NPC1
UniProt Secondary Accession #
Q5KU28; Q9NPE5
UniProt Related Accession #
Q9NPC1
GenBank Nucleotide #
NM_019839.4
NCBI Official Full Name
leukotriene B4 receptor 2
NCBI Official Synonym Full Names
leukotriene B4 receptor 2
NCBI Official Symbol
LTB4R2
NCBI Official Synonym Symbols
BLT2; NOP9; BLTR2; JULF2; KPG_004; LTB4-R2; LTB4-R 2
UniProt Protein Name
Leukotriene B4 receptor 2
UniProt Synonym Protein Names
LTB4 receptor JULF2; Leukotriene B4 receptor BLT2; Seven transmembrane receptor BLTR2
Protein Family
Leukotriene B4 receptor
UniProt Gene Name
LTB4R2
UniProt Synonym Gene Names
BLT2R; BLTR2; LTB4-R 2; LTB4-R2
UniProt Entry Name
LT4R2_HUMAN
NCBI Protein Information
leukotriene B4 receptor 2; LTB4 receptor JULF2; leukotriene B4 receptor BLT2; seven transmembrane receptor BLTR2

UniProt Comments for LTB4R2

LTB4R2: Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; Motility/polarity/chemotaxis; GPCR, family 1

Chromosomal Location of Human Ortholog: 14q12

Cellular Component: membrane; integral to plasma membrane; plasma membrane

Molecular Function: leukotriene B4 receptor activity; leukotriene receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; negative regulation of adenylate cyclase activity; chemotaxis; keratinocyte migration
Show more

Research Articles on LTB4R2

1. BLT2-NOX-ROS-NF-kappaB cascade induction during detachment confers a novel mechanism of anoikis resistance in prostate cancer cells and potentially contributes to prostate cancer progression.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-LTB4R2 antibody

 Reference Product  PubMed Publications
 LTB4R antibody  >24 publications with LTB4R2 and LTB4R

Pathways associated with anti-LTB4R2 antibody

 Products by Pathway  Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Eicosanoid Ligand-binding Receptors Pathway antibodies  Eicosanoid Ligand-binding Receptors Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Other Pathway antibodies  GPCRs, Other Pathway Diagram

Diseases associated with anti-LTB4R2 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >19 publications with LTB4R2 and Inflammation
 Disease Models, Animal Antibodies  >4 publications with LTB4R2 and Disease Models, Animal
 Necrosis Antibodies  >4 publications with LTB4R2 and Necrosis
 Nervous System Diseases Antibodies  >2 publications with LTB4R2 and Nervous System Diseases
 Brain Diseases Antibodies  >2 publications with LTB4R2 and Brain Diseases
 Kidney Diseases Antibodies  >1 publications with LTB4R2 and Kidney Diseases

Organs/Tissues associated with anti-LTB4R2 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >22 publications with LTB4R2 and Blood
 Lung Antibodies  >8 publications with LTB4R2 and Lung
 Bone Antibodies  >5 publications with LTB4R2 and Bone
 Intestine Antibodies  >3 publications with LTB4R2 and Intestine
 Ovary Antibodies  >3 publications with LTB4R2 and Ovary
 Prostate Antibodies  >2 publications with LTB4R2 and Prostate
 Embryonic Tissue Antibodies  >2 publications with LTB4R2 and Embryonic Tissue
 Kidney Antibodies  >1 publications with LTB4R2 and Kidney
 Pancreas Antibodies  >1 publications with LTB4R2 and Pancreas
 Spleen Antibodies  >1 publications with LTB4R2 and Spleen
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