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NTSR2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS244332

NTR2, a Neurotensin Receptor, is primarily expressed in brain neurons and astrocytes. It is activated by neurotensin and by levocabastine, a histamine H1 antagonist. More details

$650 / 0.05 mg +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
NTSR2 / NTR2, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human NTSR2 / NTR2
Product Gene Name
Product Synonym Gene Name
NTR2
Product Synonym Names
Anti-NTSR2 / NTR2 Antibody (Extracellular Domain) IHC-plus; NTSR2; Neurotensin NT2 receptor; Neurotensin receptor; type 2; NTR2; NT2 receptor; Neurotensin receptor 2; Neurotensin receptor type 2; NT-R-2; Human NTSR2; NTR2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gibbon, Gorilla, Human, Monkey
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human NTSR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except NTSR1 (61%).
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
45,385 Da
OMIM
605538
3D Structure
ModBase 3D Structure for O95665
Target Species
Human
Immunogen Description
Synthetic 18 amino acid peptide from 3rd extracellular domain of human NTSR2. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset (89%).
Immunogen Type
Synthetic peptide
Immunogen
NTSR2 / NTR2 antibody was raised against synthetic 18 amino acid peptide from 3rd extracellular domain of human NTSR2. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset (89%).
Antigen Modification
Extracellular Domain
Applications Tested/Suitable for anti-NTSR2 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-NTSR2 antibody
IHC-P (4 - 7 ug/ml)

Immunohistochemistry (IHC) of anti-NTSR2 antibody

Anti-NTSR2 / NTR2 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-NTSR2 Polyclonal Antibody – Cat# MBS244332

Immunohistochemistry (IHC) of anti-NTSR2 antibody

Anti-NTSR2 / NTR2 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-NTSR2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS244332

Immunohistochemistry (IHC) of anti-NTSR2 antibody

Anti-NTSR2 / NTR2 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-NTSR2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS244332

Immunohistochemistry (IHC) of anti-NTSR2 antibody

Anti-NTSR2 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-NTSR2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS244332

Other Notes

Small volumes of anti-NTSR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NTSR2 purchase

MBS244332 is an antibody targeting NTSR2. Also known as Rabbit Polyclonal to Human NTSR2 / NTR2. Reactive in Gibbon, Gorilla, Human, Monkey. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NTSR2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
neurotensin receptor type 2
NCBI Official Synonym Full Names
neurotensin receptor 2
NCBI Official Symbol
NTSR2
NCBI Official Synonym Symbols
NTR2
UniProt Protein Name
Neurotensin receptor type 2
UniProt Synonym Protein Names
Levocabastine-sensitive neurotensin receptor
Protein Family
UniProt Gene Name
NTSR2
UniProt Synonym Gene Names
NT-R-2; NTR2
UniProt Entry Name
NTR2_HUMAN
NCBI Protein Information
neurotensin receptor type 2; NT-R-2; neurotensin receptor, type 2; levocabastine-sensitive neurotensin receptor

NCBI Summary for NTSR2

The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist. [provided by RefSeq, Jul 2008]
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UniProt Comments for NTSR2

NTSR2: neurotensin receptor 2

Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2p25.1

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; neurotensin receptor activity, G-protein coupled

Biological Process: regulation of membrane potential; cell surface receptor linked signal transduction; neuropeptide signaling pathway; sensory perception; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NTSR2 antibody

Organs/Tissues associated with anti-NTSR2 antibody

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