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PDIA2 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS244339

MBS244339 is an antibody targeting PDIA2. Also known as Goat Polyclonal to Human PDIA2. Reactive in Gibbon, Gorilla, Human, OrangutanPredicted Reactivity: Monkey (at least 90% immunogen sequence identity). Host: Goat. More details

$680 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
PDIA2, Polyclonal Antibody
Full Product Name
Goat Polyclonal to Human PDIA2
Product Gene Name
Product Synonym Names
Anti-PDIA2 Antibody (Internal) IHC-plus; PDIA2; PDA2; PDIR; PDIP; Protein disulfide isomerase A2; Protein disulfide-isomerase A2; PDI; Human PDIA2
Clonality
Polyclonal
Host
Goat
Species Reactivity
Gibbon, Gorilla, Human, Orangutan
Predicted Reactivity: Monkey (at least 90% immunogen sequence identity)
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human PDIA2.
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Molecular Weight
57,850 Da
OMIM
608012
3D Structure
ModBase 3D Structure for Q13087
Target Species
Human
Immunogen Description
Synthetic peptide C-NLETTKKYAPVD from an internal region of human PDIA2 (NP_006840.2). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon (100%); Baboon, Monkey, Marmoset (92%); Panda, Pig (83%).
Immunogen Type
Synthetic peptide
Immunogen
PDIA2 antibody was raised against synthetic peptide C-NLETTKKYAPVD from an internal region of human PDIA2 (NP_006840.2). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon (100%); Baboon, Monkey, Marmoset (92%); Panda, Pig (83%).
Antigen Modification
Internal
Applications Tested/Suitable for anti-PDIA2 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-PDIA2 antibody
ELISA (1:64000), IHC-P (3.75 ug/ml), WB (0.01 - 0.03 ug/ml)

Immunohistochemistry (IHC) of anti-PDIA2 antibody

Anti-PDIA2 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Goat Anti-PDIA2 Polyclonal Antibody – Cat# MBS244339

Immunohistochemistry (IHC) of anti-PDIA2 antibody

Anti-PDIA2 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Goat Anti-PDIA2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS244339

Western Blot (WB) of anti-PDIA2 antibody

Antibody (0.03 ug/ml) staining of Human Pancreas lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-PDIA2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS244339

Other Notes

Small volumes of anti-PDIA2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PDIA2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein disulfide-isomerase A2
NCBI Official Synonym Full Names
protein disulfide isomerase family A, member 2
NCBI Official Symbol
PDIA2
NCBI Official Synonym Symbols
PDI; PDA2; PDIP; PDIR
UniProt Protein Name
Protein disulfide-isomerase A2
UniProt Synonym Protein Names
Pancreas-specific protein disulfide isomerase; PDIp
UniProt Gene Name
PDIA2
UniProt Synonym Gene Names
PDIP; PDIp
UniProt Entry Name
PDIA2_HUMAN
NCBI Protein Information
protein disulfide-isomerase A2; protein disulfide isomerase A2; Rho GDP dissociation inhibitor gamma; pancreatic protein disulfide isomerase; protein disulfide isomerase, pancreatic; protein disulfide isomerase-associated 2; pancreas-specific protein disulfide isomerase

NCBI Summary for PDIA2

Protein disulfide isomerases (EC 5.3.4.1), such as PDIP, are endoplasmic reticulum (ER) resident proteins that catalyze protein folding and thiol-disulfide interchange reactions (Desilva et al., 1996 [PubMed 8561901]).[supplied by OMIM, Mar 2008]

UniProt Comments for PDIA2

PDIA2: Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins. Belongs to the protein disulfide isomerase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Endoplasmic reticulum; Isomerase; EC 5.3.4.1

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: endoplasmic reticulum; endoplasmic reticulum lumen

Molecular Function: disulfide oxidoreductase activity; protein binding; protein disulfide isomerase activity; peptidyl-proline 4-dioxygenase activity; steroid binding

Biological Process: protein folding; cell redox homeostasis; peptidyl-proline hydroxylation; protein retention in ER
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PDIA2 antibody

 Reference Product  PubMed Publications
 LRP1 antibody  >1 publications with PDIA2 and LRP1

Pathways associated with anti-PDIA2 antibody

 Products by Pathway  Pathway Diagram
 Statin Pathway antibodies  Statin Pathway Diagram

Organs/Tissues associated with anti-PDIA2 antibody

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