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TBKBP1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS244457

MBS244457 is an antibody targeting TBKBP1. Also known as Rabbit Polyclonal to Human TBKBP1. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
TBKBP1, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human TBKBP1
Product Gene Name
Product Synonym Names
Anti-TBKBP1 Antibody (aa300-350) IHC-plus; TBKBP1; KIAA0775; TBK1 binding protein 1; ProSAPiP2; TBK1-binding protein 1; SINTBAD; Human TBKBP1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS, 0.05% BSA, 0.05% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human TBKBP1
Preparation and Storage
Store at 4 degree C for short term applications. For long term storage, aliquot and store at -20 degree C.
Molecular Weight
25,043 Da
OMIM
608476
3D Structure
ModBase 3D Structure for A7MCY6
Target Species
Human
Immunogen Description
A portion of amino acids 300-350 of human SINTBAD/TBKBP1 was used as the immunogen.
Immunogen Type
Synthetic peptide
Immunogen
TBKBP1 antibody was raised against a portion of amino acids 300-350 of human SINTBAD/TBKBP1 was used as the immunogen.
Antigen Modification
aa300-350
Applications Tested/Suitable for anti-TBKBP1 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-TBKBP1 antibody
IHC-P (10 ug/ml), WB (0.5 - 4 ug/ml)

Immunohistochemistry (IHC) of anti-TBKBP1 antibody

Anti-TBKBP1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-TBKBP1 Polyclonal Antibody – Cat# MBS244457

Western Blot (WB) of anti-TBKBP1 antibody

Western blot of SINTBAD/TBKBP1 in human brain lysate in the 1) absence and 2) presence of immunizing peptide 3) mouse brain and 4) rat brain using at 4.0 ug/ml, 0.5 ug/ml and 1.0 ug/ml, respectively. Goat anti-rabbit Ig HRP secondary antibody, and PicoTect ECL substrate solution, were used for this test.
Rabbit Anti-TBKBP1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS244457

Other Notes

Small volumes of anti-TBKBP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TBKBP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
TANK-binding kinase 1-binding protein 1
NCBI Official Synonym Full Names
TBK1 binding protein 1
NCBI Official Symbol
TBKBP1
NCBI Official Synonym Symbols
SINTBAD; ProSAPiP2
UniProt Protein Name
TANK-binding kinase 1-binding protein 1
UniProt Gene Name
TBKBP1
UniProt Synonym Gene Names
TBK1-binding protein 1
UniProt Entry Name
TBKB1_HUMAN
NCBI Protein Information
TANK-binding kinase 1-binding protein 1; TBKBP1; TBK1-binding protein 1

NCBI Summary for TBKBP1

TBKBP1 is an adaptor protein that binds to TBK1 (MIM 604834) and is part of the interaction network in the TNF (MIM 191160)/NFKB (see MIM 164011) pathway (Bouwmeester et al., 2004 [PubMed 14743216]).[supplied by OMIM, Mar 2008]

UniProt Comments for TBKBP1

TBKBP1: Adapter protein which constitutively binds TBK1 and IKBKE and may play a role in antiviral innate immunity. Homodimer. May form a heterodimer with NAP1. Interacts with TKB1 and IKBKE. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 17q21.32

Molecular Function: protein binding

Biological Process: innate immune response
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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