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TXNDC1 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS244490

MBS244490 is an antibody targeting TXNDC1. Also known as Goat Polyclonal to Human TXNDC1 / TMX1. Reactive in Gibbon, Gorilla, HumanPredicted Reactivity: Orangutan, Monkey, Bat, Bovine, Pig (at least 90% immunogen sequence identity). Host: Goat. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
TXNDC1 / TMX1, Polyclonal Antibody
Full Product Name
Goat Polyclonal to Human TXNDC1 / TMX1
Product Gene Name
Product Synonym Gene Name
TMX1
Product Synonym Names
Anti-TXNDC1 / TMX1 Antibody (C-Terminus) IHC-plus; TMX1; TXNDC1; Thioredoxin domain-containing; TXNDC; PDIA11; Thioredoxin domain containing; TMX; Human TXNDC1; TMX1
Clonality
Polyclonal
Host
Goat
Species Reactivity
Gibbon, Gorilla, Human
Predicted Reactivity: Orangutan, Monkey, Bat, Bovine, Pig (at least 90% immunogen sequence identity)
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human TMX1 / TXNDC.
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Molecular Weight
31,791 Da
OMIM
610527
3D Structure
ModBase 3D Structure for Q9H3N1
Target Species
Human
Immunogen Description
Synthetic peptide C-RSLGPSLATDKS from the C-terminus of human TMX1 / TXNDC (NP_110382.3). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Orangutan, Marmoset, Bat, Bovine, Pig (92%); Panda, Dog (83%).
Immunogen Type
Synthetic peptide
Immunogen
TXNDC1 / TMX1 antibody was raised against synthetic peptide C-RSLGPSLATDKS from the C-terminus of human TMX1 / TXNDC (NP_110382.3). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Orangutan, Marmoset, Bat, Bovine, Pig (92%); Panda, Dog (83%).
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-TXNDC1 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-TXNDC1 antibody
ELISA (1:64000), IHC-P (3.75 ug/ml), WB (1:64000, 0.01 - 0.03 ug/ml)

Immunohistochemistry (IHC) of anti-TXNDC1 antibody

Anti-TMX1 / TXNDC antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Goat Anti-TXNDC1 Polyclonal Antibody – Cat# MBS244490

Immunohistochemistry (IHC) of anti-TXNDC1 antibody

Anti-TMX1 / TXNDC antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Goat Anti-TXNDC1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS244490

Immunohistochemistry (IHC) of anti-TXNDC1 antibody

Anti-TMX1 / TXNDC antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Goat Anti-TXNDC1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS244490

Western Blot (WB) of anti-TXNDC1 antibody

Antibody (0.01 ug/ml) staining of human liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-TXNDC1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS244490

Other Notes

Small volumes of anti-TXNDC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TXNDC1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
thioredoxin-related transmembrane protein 1
NCBI Official Synonym Full Names
thioredoxin-related transmembrane protein 1
NCBI Official Symbol
TMX1
NCBI Official Synonym Symbols
TMX; TXNDC; PDIA11; TXNDC1
UniProt Protein Name
Thioredoxin-related transmembrane protein 1
UniProt Synonym Protein Names
Thioredoxin domain-containing protein 1; Transmembrane Trx-related protein
UniProt Gene Name
TMX1
UniProt Synonym Gene Names
TMX; TXNDC; TXNDC1
UniProt Entry Name
TMX1_HUMAN
NCBI Protein Information
thioredoxin-related transmembrane protein 1; thioredoxin domain containing 1; transmembrane Trx-related protein; thioredoxin domain-containing protein 1; protein disulfide isomerase family A, member 11

NCBI Summary for TXNDC1

TXNDC1 is a thioredoxin (TXN; see MIM 187700)-related protein with disulfide reductase activity (Matsuo et al., 2001 [PubMed 11152479]).[supplied by OMIM, Mar 2008]

UniProt Comments for TXNDC1

TXNDC1: May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 14q22.1

Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; integral to membrane; nucleolus

Molecular Function: disulfide oxidoreductase activity; protein disulfide isomerase activity

Biological Process: protein folding; cell redox homeostasis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-TXNDC1 antibody

Organs/Tissues associated with anti-TXNDC1 antibody

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