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IRGC1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS244499

MBS244499 is an antibody targeting IRGC1. Also known as Rabbit Polyclonal to Human IRGC1 / CINEMA. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
IRGC1 / CINEMA, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human IRGC1 / CINEMA
Product Gene Name
Product Synonym Gene Name
CINEMA; IRGC
Product Synonym Names
Anti-IRGC1 / CINEMA Antibody (C-Terminus) IHC-plus; IRGC; CINEMA; Iigp5; IFGGE; Interferon inducible GTPase 5; IRGC1; Interferon-inducible GTPase 5; R30953_1; Human IRGC1; CINEMA
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human IRGC
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
Molecular Weight
50,288 Da
3D Structure
ModBase 3D Structure for Q6NXR0
Target Species
Human
Immunogen Description
A 12 amino acid peptide near the carboxy terminus of human IRGC.
Immunogen Type
Synthetic peptide
Immunogen
IRGC1 / CINEMA antibody was raised against a 12 amino acid peptide near the carboxy terminus of human IRGC.
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-IRGC1 antibody
Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Western Blot (WB), ELISA (EIA)
Application Notes for anti-IRGC1 antibody
ELISA, ICC, IHC-P (5 ug/ml), WB (1 - 2 ug/ml)
Usage: IRGC antibody can be used for detection of IRGC by Western blot at 1-2 ug/ml.

Immunohistochemistry (IHC) of anti-IRGC1 antibody

Anti-IRGC antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-IRGC1 Polyclonal Antibody – Cat# MBS244499

Immunofluorescence (IF) of anti-IRGC1 antibody

Immunofluorescence of IRGCb in A20 cells with IRGCb antibody at 20 ug/ml.
Rabbit Anti-IRGC1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS244499

Immunocytochemistry (ICC) of anti-IRGC1 antibody

Immunocytochemistry of IRGC in A20 cells with IRGC antibody at 2.5 ug/ml.
Rabbit Anti-IRGC1 Polyclonal Antibody, Immunocytochemistry (ICC) – Cat# MBS244499

Western Blot (WB) of anti-IRGC1 antibody

Western blot of IRGC in mouse brain tissue lysate with IRGC antibody at (A) 1 and (B) 2 ug/ml.
Rabbit Anti-IRGC1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS244499

Other Notes

Small volumes of anti-IRGC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IRGC1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interferon-inducible GTPase 5
NCBI Official Synonym Full Names
immunity-related GTPase family, cinema
NCBI Official Symbol
IRGC
NCBI Official Synonym Symbols
IFGGE; IRGC1; Iigp5; CINEMA; R30953_1
UniProt Protein Name
Interferon-inducible GTPase 5
UniProt Synonym Protein Names
Immunity-related GTPase cinema 1
UniProt Gene Name
IRGC
UniProt Synonym Gene Names
IIGP5; IRGC1
UniProt Entry Name
IIGP5_HUMAN
NCBI Protein Information
interferon-inducible GTPase 5; interferon inducible GTPase 5; immunity-related GTPase cinema 1; immunity-related GTPase family, cinema 1; interferon-gamma-inducible GTPase IFGGE protein

UniProt Comments for IRGC1

IRGC: Belongs to the interferon-inducible GTPase family.

Protein type: Hydrolase; EC 3.6.5.-

Chromosomal Location of Human Ortholog: 19q13.31

Cellular Component: membrane

Molecular Function: GTP binding; hydrolase activity

Biological Process: metabolic process

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-IRGC1 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with IRGC1 and Brain
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