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NLRP14 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS244646

MBS244646 is an antibody targeting NLRP14. Also known as Rabbit Polyclonal to Human NLRP14 / NALP14. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$650 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NLRP14 / NALP14, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human NLRP14 / NALP14
Product Gene Name
Product Synonym Gene Name
NALP14
Product Synonym Names
Anti-NLRP14 / NALP14 Antibody (N-Terminus) IHC-plus; NLRP14; CLR11.2; GC-LRR; NOD5; PAN8; Nalp-iota; NALP14; Human NLRP14; NALP14
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human NLRP14
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
Molecular Weight
124,733 Da
OMIM
609665
3D Structure
ModBase 3D Structure for Q86W24
Target Species
Human
Immunogen Description
A 16 amino acid peptide near the amino terminus of human NALP14.
Immunogen Type
Synthetic peptide
Immunogen
NLRP14 / NALP14 antibody was raised against a 16 amino acid peptide near the amino terminus of human NALP14.
Antigen Modification
N-Terminus
Applications Tested/Suitable for anti-NLRP14 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-NLRP14 antibody
ELISA, IHC-P (5 ug/ml), WB (1 - 2 ug/ml)
Usage: NALP14 antibody can be used for detection of NALP14 by Western blot at 1-2 ug/ml.

Immunohistochemistry (IHC) of anti-NLRP14 antibody

Anti-NLRP14 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-NLRP14 Polyclonal Antibody – Cat# MBS244646

Immunohistochemistry (IHC) of anti-NLRP14 antibody

Anti-NLRP14 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-NLRP14 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS244646

Western Blot (WB) of anti-NLRP14 antibody

Western blot analysis of NALP14 in rat brain tissue lysate with NALP14 antibody at 1 ug/ml.
Rabbit Anti-NLRP14 Polyclonal Antibody, Western Blot (WB) – Cat# MBS244646

Other Notes

Small volumes of anti-NLRP14 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NLRP14. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
NACHT, LRR and PYD domains-containing protein 14
NCBI Official Synonym Full Names
NLR family, pyrin domain containing 14
NCBI Official Symbol
NLRP14
NCBI Official Synonym Symbols
NOD5; PAN8; GC-LRR; NALP14; CLR11.2
UniProt Protein Name
NACHT, LRR and PYD domains-containing protein 14
UniProt Synonym Protein Names
Nucleotide-binding oligomerization domain protein 5
UniProt Gene Name
NLRP14
UniProt Synonym Gene Names
NALP14; NOD5
UniProt Entry Name
NAL14_HUMAN
NCBI Protein Information
NACHT, LRR and PYD domains-containing protein 14; NACHT, LRR and PYD containing protein 14; NACHT, leucine rich repeat and PYD containing 14; nucleotide-binding oligomerization domain protein 5; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 14

NCBI Summary for NLRP14

The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq, Jul 2008]
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UniProt Comments for NLRP14

NLRP14: May be involved in inflammation and spermatogenesis. Belongs to the NLRP family.

Chromosomal Location of Human Ortholog: 11p15.4

Molecular Function: ATP binding

Biological Process: multicellular organismal development; spermatogenesis; cell differentiation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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