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CA1 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS244737

MBS244737 is an antibody targeting CA1. Also known as Goat Polyclonal to Human CA1 / Carbonic Anhydrase I. Reactive in Gibbon, Chimpanzee, Gorilla, HumanPredicted Reactivity: Monkey (at least 90% immunogen sequence identity). Host: Goat. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CA1 / Carbonic Anhydrase I, Polyclonal Antibody
Full Product Name
Goat Polyclonal to Human CA1 / Carbonic Anhydrase I
Product Gene Name
Product Synonym Names
Anti-CA1 / Carbonic Anhydrase I Antibody IHC-plus; CA1; CAB; Carbonic anhydrase 1; CAR1; Carbonate dehydratase I; Carbonic dehydratase; CA-I; Carbonic anhydrase B; Carbonic anhydrase I; Human CA1; Carbonic Anhydrase I
Clonality
Polyclonal
Host
Goat
Species Reactivity
Gibbon, Chimpanzee, Gorilla, Human
Predicted Reactivity: Monkey (at least 90% immunogen sequence identity)
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human CA1 / Carbonic Anhydrase I. Reported variants represent identical protein: NP_001729.1, NP_001122303.1, NP_001122302.1, NP_001122301.1.
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
Molecular Weight
28,870 Da
OMIM
114800
3D Structure
ModBase 3D Structure for P00915
Target Species
Human
Immunogen Description
Synthetic peptide C-QAIKTKGKRAP from an internal region of human CA1 / Carbonic Anhydrase I (NP_001729.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon (100%); Monkey, Elephant (91%); Marmoset (82%).
Immunogen Type
Synthetic peptide
Immunogen
CA1 / Carbonic Anhydrase I antibody was raised against synthetic peptide C-QAIKTKGKRAP from an internal region of human CA1 / Carbonic Anhydrase I (NP_001729.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon (100%); Monkey, Elephant (91%); Marmoset (82%).
Applications Tested/Suitable for anti-CA1 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-CA1 antibody
ELISA (1:64000), IHC-P (2.5 ug/ml), WB (0.03 - 0.1 ug/ml)

Immunohistochemistry (IHC) of anti-CA1 antibody

Anti-CA1 / Carbonic Anhydrase I antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
Goat Anti-CA1 Polyclonal Antibody – Cat# MBS244737

Western Blot (WB) of anti-CA1 antibody

Staining (0.03 ug/ml) of Human Liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-CA1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS244737

Other Notes

Small volumes of anti-CA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CA1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
carbonic anhydrase 1 isoform a
NCBI Official Synonym Full Names
carbonic anhydrase I
NCBI Official Symbol
CA1
NCBI Official Synonym Symbols
CAB; CA-I; Car1; HEL-S-11
UniProt Protein Name
Carbonic anhydrase 1
UniProt Synonym Protein Names
Carbonate dehydratase I; Carbonic anhydrase B; CAB; Carbonic anhydrase I; CA-I
Protein Family
UniProt Gene Name
CA1
UniProt Synonym Gene Names
CAB; CA-I
UniProt Entry Name
CAH1_HUMAN
NCBI Protein Information
carbonic anhydrase 1; carbonic anhydrase B; carbonate dehydratase I; epididymis secretory protein Li 11

NCBI Summary for CA1

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This CA1 gene is closely linked to the CA2 and CA3 genes on chromosome 8. It encodes a cytosolic protein that is found at the highest level in erythrocytes. Allelic variants of this gene have been described in some populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
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UniProt Comments for CA1

CA1: Reversible hydration of carbon dioxide. Can hydrates cyanamide to urea. Belongs to the alpha-carbonic anhydrase family.

Protein type: Energy Metabolism - nitrogen; Lyase; EC 4.2.1.1

Chromosomal Location of Human Ortholog: 8q21.2

Cellular Component: cytosol

Molecular Function: carbonate dehydratase activity; zinc ion binding

Biological Process: bicarbonate transport; one-carbon compound metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CA1 antibody

 Reference Product  PubMed Publications
 MYB antibody  >2 publications with CA1 and MYB
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