Goat Anti-SLC2A5 Polyclonal Antibody – Cat# MBS244792

Anti-SLC2A5 / GLUT5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.

SLC2A5 Antibody – Goat Polyclonal

Name: SLC2A5 Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS244792
Price: 625 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS244792

SLC2A5/GLUT5 belongs to a family of glucose/fructose transport proteins that exhibit 45-65% amino acid homology. GLUT 5 functions mainly as a fructose transporter and is thought to be largely responsible for the uptake of fructose from the lumen of the small… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

SLC2A5 / GLUT5, Polyclonal Antibody

Full Product Name

Goat Polyclonal to Human SLC2A5 / GLUT5

Product Gene Name

anti-SLC2A5 antibody

Product Synonym Gene Name

GLUT5

Product Synonym Names

Anti-SLC2A5 / GLUT5 Antibody (C-Terminus) IHC-plus; SLC2A5; Fructose transporter; Glucose transporter 5; GLUT-5; GLUT5; Human SLC2A5; GLUT5

Clonality

Polyclonal

Host

Goat

Species Reactivity

Human, Orangutan
Predicted Reactivity: Gorilla, Monkey (at least 90% immunogen sequence identity)

Form/Format

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide

Purity/Purification

Immunoaffinity Purified

Concentration

0.5 mg/ml (lot specific)

Specificity

Human SLC2A5 / GLUT5.

Preparation and Storage

Store at -20 degree C. Minimize freezing and thawing.

Molecular Weight

26,519 Da

OMIM

138230

3D Structure

ModBase 3D Structure for P22732

Target Species

Human

Immunogen Description

Synthetic peptide C-SEVYPEKEELKE from the C-terminus of human SLC2A5 / GLUT5 (NP_003030.1). Percent identity by BLAST analysis: Human, Orangutan, Marmoset (100%); Gorilla, Monkey (92%); Rat, Elephant, Panda, Dog (83%).

Immunogen Type

Synthetic peptide

Immunogen

SLC2A5 / GLUT5 antibody was raised against synthetic peptide C-SEVYPEKEELKE from the C-terminus of human SLC2A5 / GLUT5 (NP_003030.1). Percent identity by BLAST analysis: Human, Orangutan, Marmoset (100%); Gorilla, Monkey (92%); Rat, Elephant, Panda, Dog (83%).

Antigen Modification

C-Terminus

Product Categories/Family for anti-SLC2A5 antibody

Family: Transporter; Subfamily: Sugar transporter

Applications Tested/Suitable for anti-SLC2A5 antibody

Immunohistochemistry (IHC - Paraffin)

Application Notes for anti-SLC2A5 antibody

IHC-P (2.5 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Other Notes

Small volumes of anti-SLC2A5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLC2A5 purchase

MBS244792 is an antibody targeting SLC2A5. Also known as Goat Polyclonal to Human SLC2A5 / GLUT5. Reactive in Human, Orangutan
Predicted Reactivity: Gorilla, Monkey (at least 90% immunogen sequence identity). Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC2A5. It may not necessarily be applicable to this product.

NCBI GI #

4507013

NCBI GeneID

6518

NCBI Accession #

NP_003030.1

UniProt Primary Accession #

P22732

UniProt Secondary Accession #

Q14770; Q5T977; Q8IVB3

UniProt Related Accession #

P22732

GenBank Nucleotide #

NM_003039.2

NCBI Official Full Name

solute carrier family 2, facilitated glucose transporter member 5 isoform 1

NCBI Official Synonym Full Names

solute carrier family 2 (facilitated glucose/fructose transporter), member 5

NCBI Official Symbol

SLC2A5

NCBI Official Synonym Symbols

GLUT5; GLUT-5

UniProt Protein Name

Solute carrier family 2, facilitated glucose transporter member 5

UniProt Synonym Protein Names

Fructose transporter; Glucose transporter type 5, small intestine; GLUT-5

Protein Family

Solute carrier family

UniProt Gene Name

SLC2A5

UniProt Synonym Gene Names

GLUT5; GLUT-5

UniProt Entry Name

GTR5_HUMAN

NCBI Protein Information

solute carrier family 2, facilitated glucose transporter member 5; glucose transporter-like protein 5; glucose transporter type 5, small intestine

UniProt Comments for SLC2A5

GLUT5: an integral membrane facilitative glucose transporter. One of 13 members of the human equilibrative glucose transport protein family. Plays an important role in fructose absorption by the intestine. Expressed primarily in the jejunal region of the small intestine. Expressed at low levels in human kidney, skeletal muscle, adipocytes, microglial cells and in the human blood-brain barrier.

Protein type: Membrane protein, multi-pass; Transporter; Transporter, SLC family; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p36.2

Cellular Component: apical plasma membrane; integral to membrane; plasma membrane

Molecular Function: fructose transmembrane transporter activity; glucose transmembrane transporter activity

Biological Process: hexose transport; fructose transport; carbohydrate metabolic process; pathogenesis; glucose transport; transmembrane transport

Research Articles on SLC2A5

1. SGLT1 and GLUT5 expression in the plasma membrane is regulated by TNFalpha, leading to alteration on sugar transport, suggesting that TNFalpha could be a physiological local regulator of nutrient absorption in response to an intestinal inflammatory status.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SLC2A5 antibody

Reference Product	PubMed Publications
SLC2A2 antibody	>17 publications with SLC2A5 and SLC2A2
SLC5A1 antibody	>15 publications with SLC2A5 and SLC5A1
CA2 antibody	>1 publications with SLC2A5 and CA2
ENO1 antibody	>1 publications with SLC2A5 and ENO1
CA6 antibody	>1 publications with SLC2A5 and CA6
SLC26A5 antibody	>1 publications with SLC2A5 and SLC26A5

Pathways associated with anti-SLC2A5 antibody

Products by Pathway	Pathway Diagram
Carbohydrate Digestion And Absorption Pathway antibodies	Carbohydrate Digestion And Absorption Pathway Diagram
Carbohydrate Digestion And Absorption Pathway antibodies	Carbohydrate Digestion And Absorption Pathway Diagram
Class II GLUTs Pathway antibodies	Class II GLUTs Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Facilitative Na+-independent Glucose Transporters Pathway antibodies	Facilitative Na+-independent Glucose Transporters Pathway Diagram
Glycogen Storage Diseases Pathway antibodies	Glycogen Storage Diseases Pathway Diagram
Glycolysis And Gluconeogenesis Pathway antibodies	Glycolysis And Gluconeogenesis Pathway Diagram
Hexose Transport Pathway antibodies	Hexose Transport Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Carbohydrates Pathway antibodies	Metabolism Of Carbohydrates Pathway Diagram

Diseases associated with anti-SLC2A5 antibody

Disease Name	Pubmed Publications
Hypertension Antibodies	>9 publications with SLC2A5 and Hypertension
Insulin Resistance Antibodies	>5 publications with SLC2A5 and Insulin Resistance
Kidney Diseases Antibodies	>4 publications with SLC2A5 and Kidney Diseases
Necrosis Antibodies	>4 publications with SLC2A5 and Necrosis
Fibrosis Antibodies	>2 publications with SLC2A5 and Fibrosis
Fatty Liver Antibodies	>2 publications with SLC2A5 and Fatty Liver
Liver Diseases Antibodies	>2 publications with SLC2A5 and Liver Diseases
Inflammation Antibodies	>2 publications with SLC2A5 and Inflammation
Weight Gain Antibodies	>2 publications with SLC2A5 and Weight Gain
Hypertrophy Antibodies	>2 publications with SLC2A5 and Hypertrophy

Organs/Tissues associated with anti-SLC2A5 antibody

Organ/Tissue Name	Pubmed Publications
Intestine Antibodies	>24 publications with SLC2A5 and Intestine
Kidney Antibodies	>9 publications with SLC2A5 and Kidney
Blood Antibodies	>8 publications with SLC2A5 and Blood
Muscle Antibodies	>8 publications with SLC2A5 and Muscle
Brain Antibodies	>5 publications with SLC2A5 and Brain
Heart Antibodies	>3 publications with SLC2A5 and Heart
Uterus Antibodies	>3 publications with SLC2A5 and Uterus
Ovary Antibodies	>3 publications with SLC2A5 and Ovary
Testis Antibodies	>3 publications with SLC2A5 and Testis
Placenta Antibodies	>2 publications with SLC2A5 and Placenta