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OXER1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS244794

MBS244794 is an antibody targeting OXER1. Also known as Rabbit Polyclonal to Human OXER1. Reactive in Gorilla, Human, Monkey. Host: Rabbit. OXER1 is a Chemoattractant Receptor for eosinophils and neutrophils. More details

$650 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
OXER1, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human OXER1
Product Gene Name
anti-OXER1 antibody
Product Synonym Names
Anti-OXER1 Antibody (C-Terminus) IHC-plus; OXER1; GPR170; G-protein coupled receptor 170; HEOAD54; Oxoeicosanoid (OXE) receptor 1; Oxoeicosanoid receptor 1; TG1019; Human OXER1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gorilla, Human, Monkey
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human OXER1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
45,811 Da
3D Structure
ModBase 3D Structure for Q8TDS5
Target Species
Human
Immunogen Description
Synthetic 19 amino acid peptide from C-terminus of human OXER1. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey (100%).
Immunogen Type
Synthetic peptide
Immunogen
OXER1 antibody was raised against synthetic 19 amino acid peptide from C-terminus of human OXER1. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey (100%).
Antigen Modification
C-Terminus

Product Categories/Family for anti-OXER1 antibody

Family: GPCR; Subfamily: Chemoattractant
Applications Tested/Suitable for anti-OXER1 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-OXER1 antibody
IHC-P (30 ug/ml)

Immunohistochemistry (IHC) of anti-OXER1 antibody

Anti-OXER1 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-OXER1 Polyclonal Antibody – Cat# MBS244794

Immunohistochemistry (IHC) of anti-OXER1 antibody

Anti-OXER1 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-OXER1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS244794

Immunohistochemistry (IHC) of anti-OXER1 antibody

Anti-OXER1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-OXER1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS244794

Other Notes

Small volumes of anti-OXER1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for OXER1. It may not necessarily be applicable to this product.

NCBI GI #
22507376
NCBI GeneID
165140
NCBI Accession #
NP_683765.1
UniProt Primary Accession #
Q8TDS5
UniProt Secondary Accession #
Q86WP7; Q8NGW4
UniProt Related Accession #
Q8TDS5
GenBank Nucleotide #
NM_148962.4
NCBI Official Full Name
oxoeicosanoid receptor 1
NCBI Official Synonym Full Names
oxoeicosanoid (OXE) receptor 1
NCBI Official Symbol
OXER1
NCBI Official Synonym Symbols
GPCR; GPR170; TG1019
UniProt Protein Name
Oxoeicosanoid receptor 1
UniProt Synonym Protein Names
5-oxo-ETE G-protein coupled receptor; G-protein coupled receptor 170; G-protein coupled receptor R527; G-protein coupled receptor TG1019
Protein Family
Oxoeicosanoid receptor
UniProt Gene Name
OXER1
UniProt Synonym Gene Names
GPR170; TG1019
UniProt Entry Name
OXER1_HUMAN
NCBI Protein Information
oxoeicosanoid receptor 1; G-protein coupled receptor 170; G-protein coupled receptor R527; G-protein coupled receptor TG1019; 5-oxo-ETE G-protein coupled receptor; 5-oxo-ETE acid G-protein-coupled receptor 1

UniProt Comments for OXER1

OXER1: Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 2p21

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding; 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding; 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding

Biological Process: G-protein coupled receptor protein signaling pathway; regulation of cAMP biosynthetic process
Show more

Research Articles on OXER1

1. Gue1654 as a non-Galphai-biased antagonist of OXE-R that provides a new basis for therapeutic intervention in inflammatory diseases that involve activation of eosinophils, neutrophils, and monocytes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-OXER1 antibody

 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Eicosanoid Ligand-binding Receptors Pathway antibodies  Eicosanoid Ligand-binding Receptors Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Metabolic Disorders Of Biological Oxidation Enzymes Pathway antibodies  Metabolic Disorders Of Biological Oxidation Enzymes Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram

Diseases associated with anti-OXER1 antibody

 Disease Name  Pubmed Publications
 Prostatic Neoplasms Antibodies  >2 publications with OXER1 and Prostatic Neoplasms
 Immune System Diseases Antibodies  >1 publications with OXER1 and Immune System Diseases
 Respiratory Tract Diseases Antibodies  >1 publications with OXER1 and Respiratory Tract Diseases

Organs/Tissues associated with anti-OXER1 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >4 publications with OXER1 and Blood
 Skin Antibodies  >1 publications with OXER1 and Skin
 Lung Antibodies  >1 publications with OXER1 and Lung
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