• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

EIF4B Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS244846

MBS244846 is an antibody targeting EIF4B. Also known as Rabbit Polyclonal to Human EIF4B. Reactive in Bovine, Chicken, Human, Mouse, Orangutan, Rat. Host: Rabbit. More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Product Name
EIF4B, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human EIF4B
Product Gene Name
anti-EIF4B antibody
Product Synonym Names
Anti-EIF4B Antibody (aa150-200) IHC-plus; EIF4B; EIF-4B; PRO1843; Human EIF4B
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Bovine, Chicken, Human, Mouse, Orangutan, Rat
Form/Format
PBS, 0.05% BSA, 0.05% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human EIF4B
Preparation and Storage
Store at 4 degree C for short term applications. For long term storage, aliquot and store at -20 degree C.
Molecular Weight
64,805 Da
OMIM
603928
3D Structure
ModBase 3D Structure for P23588
Target Species
Human
Immunogen Description
A portion of amino acids 150-200 of human eIF4B was used as the immunogen.
Immunogen Type
Synthetic peptide
Immunogen
EIF4B antibody was raised against a portion of amino acids 150-200 of human eIF4B was used as the immunogen.
Antigen Modification
aa150-200
Applications Tested/Suitable for anti-EIF4B antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-EIF4B antibody
IHC-P (10 ug/ml), WB (0.25 - 0.5 ug/ml)

Immunohistochemistry (IHC) of anti-EIF4B antibody

Anti-EIF4B antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-EIF4B Polyclonal Antibody – Cat# MBS244846

Immunohistochemistry (IHC) of anti-EIF4B antibody

Anti-EIF4B antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-EIF4B Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS244846

Western Blot (WB) of anti-EIF4B antibody

Western blot of eIF4B in HeLa cell lysate in the 1) absence, 2) presence of immunizing peptide and 3) RAW using at 0.25 ug/ml.
Rabbit Anti-EIF4B Polyclonal Antibody, Western Blot (WB) – Cat# MBS244846

Other Notes

Small volumes of anti-EIF4B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for EIF4B. It may not necessarily be applicable to this product.

NCBI GI #
50053795
NCBI GeneID
1975
NCBI Accession #
NP_001408.2
UniProt Primary Accession #
P23588
UniProt Secondary Accession #
Q4G0E3; Q53HQ2; Q6GPH5; Q6IB46; Q8WYK5; B4DS13
UniProt Related Accession #
P23588
GenBank Nucleotide #
NM_001417.5
NCBI Official Full Name
eukaryotic translation initiation factor 4B isoform 2
NCBI Official Synonym Full Names
eukaryotic translation initiation factor 4B
NCBI Official Symbol
EIF4B
NCBI Official Synonym Symbols
EIF-4B; PRO1843
UniProt Protein Name
Eukaryotic translation initiation factor 4B
Protein Family
Eukaryotic translation initiation factor
UniProt Gene Name
EIF4B
UniProt Synonym Gene Names
eIF-4B
UniProt Entry Name
IF4B_HUMAN
NCBI Protein Information
eukaryotic translation initiation factor 4B

UniProt Comments for EIF4B

EIF4B: eukaryotic translation initiation factor 4B. Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.

Protein type: Translation initiation; Translation; RNA-binding

Chromosomal Location of Human Ortholog: 12q13.13

Cellular Component: eukaryotic translation initiation factor 4F complex; cytosol

Molecular Function: protein binding; RNA binding; translation initiation factor activity; nucleotide binding

Biological Process: poly(A) tail shortening; cellular protein metabolic process; translation; translational initiation; insulin receptor signaling pathway; gene expression; mRNA catabolic process, deadenylation-dependent decay; regulation of translational initiation
Show more

Research Articles on EIF4B

1. The protein level of eukaryotic translation initiation factor 4B (eIF4B) was dramatically reduced in A549 cells as well as in the lung, spleen, and thymus of mice infected with influenza A virus.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-EIF4B antibody

 Reference Product  PubMed Publications
 EIF4E antibody  >51 publications with EIF4B and EIF4E
 EIF4G1 antibody  >10 publications with EIF4B and EIF4G1
 EIF5 antibody  >6 publications with EIF4B and EIF5
 EIF3G antibody  >2 publications with EIF4B and EIF3G
 EIF3B antibody  >1 publications with EIF4B and EIF3B
 RPS6KB1 antibody  >1 publications with EIF4B and RPS6KB1

Pathways associated with anti-EIF4B antibody

 Products by Pathway  Pathway Diagram
 Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway antibodies  Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway Diagram
 Cap-dependent Translation Initiation Pathway antibodies  Cap-dependent Translation Initiation Pathway Diagram
 Deadenylation Of MRNA Pathway antibodies  Deadenylation Of MRNA Pathway Diagram
 Deadenylation-dependent MRNA Decay Pathway antibodies  Deadenylation-dependent MRNA Decay Pathway Diagram
 Eukaryotic Translation Initiation Pathway antibodies  Eukaryotic Translation Initiation Pathway Diagram
 GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway antibodies  GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 IGF1R Signaling Cascade Pathway antibodies  IGF1R Signaling Cascade Pathway Diagram
 IRS-mediated Signalling Pathway antibodies  IRS-mediated Signalling Pathway Diagram
 IRS-related Events Pathway antibodies  IRS-related Events Pathway Diagram

Diseases associated with anti-EIF4B antibody

 Disease Name  Pubmed Publications
 Cell Transformation, Neoplastic Antibodies  >8 publications with EIF4B and Cell Transformation, Neoplastic
 Necrosis Antibodies  >8 publications with EIF4B and Necrosis
 Disease Models, Animal Antibodies  >4 publications with EIF4B and Disease Models, Animal
 Neoplasm Metastasis Antibodies  >3 publications with EIF4B and Neoplasm Metastasis
 Kidney Diseases Antibodies  >3 publications with EIF4B and Kidney Diseases
 Neoplasms, Experimental Antibodies  >2 publications with EIF4B and Neoplasms, Experimental
 Cardiovascular Diseases Antibodies  >2 publications with EIF4B and Cardiovascular Diseases
 Weight Loss Antibodies  >2 publications with EIF4B and Weight Loss
 Atherosclerosis Antibodies  >1 publications with EIF4B and Atherosclerosis
 Hypertension Antibodies  >1 publications with EIF4B and Hypertension

Organs/Tissues associated with anti-EIF4B antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >38 publications with EIF4B and Blood
 Mouth Antibodies  >12 publications with EIF4B and Mouth
 Liver Antibodies  >10 publications with EIF4B and Liver
 Muscle Antibodies  >8 publications with EIF4B and Muscle
 Lung Antibodies  >7 publications with EIF4B and Lung
 Vascular Antibodies  >6 publications with EIF4B and Vascular
 Brain Antibodies  >5 publications with EIF4B and Brain
 Prostate Antibodies  >4 publications with EIF4B and Prostate
 Kidney Antibodies  >3 publications with EIF4B and Kidney
 Skin Antibodies  >3 publications with EIF4B and Skin
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000