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BAI2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS244848

BAI2 is an Orphan-B GPCR with an unknown ligand. Decreased BAI2 expression is correlated with the formation of new blood vessels in a murine ischemic model. Along with BAI2, there are two other brain-specific angiogenesis inhibitor genes, designated BAI1 and… More details

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Product Overview

Online Datasheet in PDF
Product Name
BAI2, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human BAI2
Product Gene Name
Product Synonym Names
Anti-BAI2 Antibody (C-Terminus) IHC-plus; BAI2; Human BAI2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gibbon, Chimpanzee, Guinea pig, Gorilla, Human, Monkey, Orangutan
Predicted Reactivity: Mouse, Rat, Dog, Hamster, Pig (at least 90% immunogen sequence identity)
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human BAI2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PNMAL1 (53%).
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
169,199 Da
OMIM
602683
3D Structure
ModBase 3D Structure for O60241
Target Species
Human
Immunogen Description
Synthetic 17 amino acid peptide from C-terminus of human BAI2. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Guinea pig (100%).
Immunogen Type
Synthetic peptide
Immunogen
BAI2 antibody was raised against synthetic 17 amino acid peptide from C-terminus of human BAI2. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Guinea pig (100%); Mouse, Rat, Hamster, Panda, Dog, Pig (94%); Elephant, Bovine, Horse (88%); Bat, Rabbit (82%).
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-BAI2 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-BAI2 antibody
IHC-P (10 ug/ml)

Immunohistochemistry (IHC) of anti-BAI2 antibody

Anti-BAI2 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-BAI2 Polyclonal Antibody – Cat# MBS244848

Immunohistochemistry (IHC) of anti-BAI2 antibody

Anti-BAI2 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-BAI2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS244848

Immunohistochemistry (IHC) of anti-BAI2 antibody

Anti-BAI2 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-BAI2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS244848

Immunohistochemistry (IHC) of anti-BAI2 antibody

Anti-BAI2 antibody IHC of human brain, neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-BAI2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS244848

Other Notes

Small volumes of anti-BAI2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BAI2 purchase

MBS244848 is an antibody targeting BAI2. Also known as Rabbit Polyclonal to Human BAI2. Reactive in Gibbon, Chimpanzee, Guinea pig, Gorilla, Human, Monkey, Orangutan
Predicted Reactivity: Mouse, Rat, Dog, Hamster, Pig (at least 90% immunogen sequence identity). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BAI2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
brain-specific angiogenesis inhibitor 2 isoform 1 preproprotein
NCBI Official Synonym Full Names
brain-specific angiogenesis inhibitor 2
NCBI Official Symbol
BAI2
UniProt Protein Name
Brain-specific angiogenesis inhibitor 2
UniProt Gene Name
BAI2
UniProt Entry Name
BAI2_HUMAN
NCBI Protein Information
brain-specific angiogenesis inhibitor 2

NCBI Summary for BAI2

This gene encodes a a seven-span transmembrane protein that is thought to be a member of the secretin receptor family. The encoded protein is a brain-specific inhibitor of angiogenesis. The mature peptide may be further cleaved into additional products (PMID:20367554). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
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UniProt Comments for BAI2

BAI2: Might be involved in angiogenesis inhibition. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, GPCR; GPCR, family 2; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1p35

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; negative regulation of angiogenesis; peripheral nervous system development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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