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TMEM16B Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS244900

MBS244900 is an antibody targeting TMEM16B. Also known as Rabbit Polyclonal to Human TMEM16B / ANO2. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$650 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TMEM16B / ANO2, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human TMEM16B / ANO2
Product Gene Name
Product Synonym Gene Name
ANO2
Product Synonym Names
Anti-TMEM16B / ANO2 Antibody (N-Terminus) IHC-plus; ANO2; Anoctamin 2; Anoctamin-2; C12orf3; Transmembrane protein 16B; TMEM16B; Human TMEM16B; ANO2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human ANO2
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
Molecular Weight
113,616 Da
OMIM
610109
3D Structure
ModBase 3D Structure for Q9NQ90
Target Species
Human
Immunogen Description
A 19 amino acid peptide from near the amino terminus of human TMEM16B.
Immunogen Type
Synthetic peptide
Immunogen
TMEM16B / ANO2 antibody was raised against a 19 amino acid peptide from near the amino terminus of human TMEM16B.
Antigen Modification
N-Terminus
Applications Tested/Suitable for anti-TMEM16B antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-TMEM16B antibody
ELISA, IHC-P (5 ug/ml), WB (1 - 2 ug/ml)
Usage: TMEM16B antibody can be used for detection of TMEM16B by Western blot at 1-2 ug/ml.

Immunohistochemistry (IHC) of anti-TMEM16B antibody

Anti-TMEM16B antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-TMEM16B Polyclonal Antibody – Cat# MBS244900

Immunohistochemistry (IHC) of anti-TMEM16B antibody

Anti-TMEM16B antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-TMEM16B Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS244900

Immunofluorescence (IF) of anti-TMEM16B antibody

Immunofluorescence of TMEM16B in Human Brain cells with TMEM16B antibody at 20 ug/ml.
Rabbit Anti-TMEM16B Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS244900

Western Blot (WB) of anti-TMEM16B antibody

Western blot of TMEM16B in rat brain tissue lysate with TMEM16B antibody at (A) 1 and (B) 2 ug/ml.
Rabbit Anti-TMEM16B Polyclonal Antibody, Western Blot (WB) – Cat# MBS244900

Other Notes

Small volumes of anti-TMEM16B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TMEM16B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Synonym Full Names
anoctamin 2, calcium activated chloride channel
NCBI Official Symbol
ANO2
NCBI Official Synonym Symbols
C12orf3; TMEM16B
UniProt Protein Name
Anoctamin-2
UniProt Synonym Protein Names
Transmembrane protein 16B
UniProt Gene Name
ANO2
UniProt Synonym Gene Names
C12orf3; TMEM16B
UniProt Entry Name
ANO2_HUMAN
NCBI Protein Information
anoctamin-2

NCBI Summary for TMEM16B

ANO2 belongs to a family of calcium-activated chloride channels (CaCCs) (reviewed by Hartzell et al., 2009 [PubMed 19015192]).[supplied by OMIM, Jan 2011]

UniProt Comments for TMEM16B

ANO2: Acts as a calcium-activated chloride channel (CaCC), mostly in photoreceptors. May mediate olfactory amplification in olfactory sensory neurons (OSNs) and light perception amplification in retina. Belongs to the anoctamin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter, ion channel; Transporter; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 12p13.3

Cellular Component: nucleoplasm; nonmotile primary cilium; plasma membrane

Molecular Function: protein homodimerization activity; intracellular calcium activated chloride channel activity; protein heterodimerization activity

Biological Process: transmembrane transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TMEM16B antibody

 Reference Product  PubMed Publications
 CLCA2 antibody  >1 publications with TMEM16B and CLCA2

Diseases associated with anti-TMEM16B antibody

Organs/Tissues associated with anti-TMEM16B antibody

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