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EPHA6 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS244936

MBS244936 is an antibody targeting EPHA6. Also known as Rabbit Polyclonal (IgG) to Human EPHA6 / EPH Receptor A6. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$650 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
EPHA6 / EPH Receptor A6, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal (IgG) to Human EPHA6 / EPH Receptor A6
Product Gene Name
anti-EPHA6 antibody
Product Synonym Names
Anti-EPHA6 / EPH Receptor A6 Antibody (aa891-940) IHC-plus; EPHA6; Ephrin receptor EphA6; EPA6; EPH-like kinase 12; EHK2; Ek1; Ephrin type-A receptor 6; EHK-2; EK12; EPH homology kinase 2; EPH receptor A6; HEK12; PRO57066; Human EPHA6; EPH Receptor A6
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
EPHA6 Antibody detects endogenous levels of total EPHA6 protein.
Preparation and Storage
Store at -20 degree C for up to one year.
Molecular Weight
44,466 Da
OMIM
600066
3D Structure
ModBase 3D Structure for Q9UF33
Target Species
Human
Immunogen Description
Synthetic peptide from human EPHA6 (aa891-940).
Immunogen
EPHA6 / EPH Receptor A6 antibody was raised against synthetic peptide from human EPHA6 (aa891-940).
Antigen Modification
aa891-940

Product Categories/Family for anti-EPHA6 antibody

Family: Protein Kinase; Subfamily: Ephrin Receptor
Applications Tested/Suitable for anti-EPHA6 antibody
Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-EPHA6 antibody
ELISA (1:20000), IF (1:100 - 1:500), IHC-P (10 ug/ml)

Immunohistochemistry (IHC) of anti-EPHA6 antibody

Anti-EPHA6 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-EPHA6 Polyclonal Antibody – Cat# MBS244936

Immunohistochemistry (IHC) of anti-EPHA6 antibody

Anti-EPHA6 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-EPHA6 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS244936

Immunofluorescence (IF) of anti-EPHA6 antibody

Immunofluorescence of COS7 cells, using EPHA6 Antibody. The picture on the right is treated with the synthesized peptide.
Rabbit Anti-EPHA6 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS244936

Other Notes

Small volumes of anti-EPHA6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for EPHA6. It may not necessarily be applicable to this product.

NCBI GI #
507144073
NCBI GeneID
285220
NCBI Accession #
NP_001265229.1
UniProt Primary Accession #
Q9UF33
UniProt Secondary Accession #
D6RAL5
UniProt Related Accession #
Q9UF33
GenBank Nucleotide #
NM_001278300.1
NCBI Official Full Name
ephrin type-A receptor 6 isoform c
NCBI Official Synonym Full Names
EPH receptor A6
NCBI Official Symbol
EPHA6
NCBI Official Synonym Symbols
EHK2; EK12; EPA6; EHK-2; HEK12; PRO57066
UniProt Protein Name
Ephrin type-A receptor 6
UniProt Synonym Protein Names
EPH homology kinase 2; EHK-2; EPH-like kinase 12; EK12
Protein Family
Ephrin type-A receptor
UniProt Gene Name
EPHA6
UniProt Synonym Gene Names
EHK2; HEK12; EHK-2; EK12
UniProt Entry Name
EPHA6_HUMAN
NCBI Protein Information
ephrin type-A receptor 6; EPH-like kinase 12; EPH homology kinase 2; ephrin receptor EphA6

UniProt Comments for EPHA6

EphA6: Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Protein kinase, TK; EC 2.7.10.1; Membrane protein, integral; Protein kinase, tyrosine (receptor); Kinase, protein; TK group; Eph family

Chromosomal Location of Human Ortholog: 3q11.2

Cellular Component: nucleoplasm; integral to plasma membrane; plasma membrane

Molecular Function: ephrin receptor activity; ATP binding

Biological Process: axon guidance; peptidyl-tyrosine phosphorylation; ephrin receptor signaling pathway
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Research Articles on EPHA6

1. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-EPHA6 antibody

 Reference Product  PubMed Publications
 EFNB1 antibody  >1 publications with EPHA6 and EFNB1
 EFNB2 antibody  >1 publications with EPHA6 and EFNB2
 EFNA3 antibody  >1 publications with EPHA6 and EFNA3
 EFNA1 antibody  >1 publications with EPHA6 and EFNA1
 EFNA5 antibody  >1 publications with EPHA6 and EFNA5

Pathways associated with anti-EPHA6 antibody

 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 EPH-Ephrin Signaling Pathway antibodies  EPH-Ephrin Signaling Pathway Diagram
 EPH-ephrin Mediated Repulsion Of Cells Pathway antibodies  EPH-ephrin Mediated Repulsion Of Cells Pathway Diagram
 EPHA Forward Signaling Pathway antibodies  EPHA Forward Signaling Pathway Diagram
 EPHA-mediated Growth Cone Collapse Pathway antibodies  EPHA-mediated Growth Cone Collapse Pathway Diagram
 EphrinA-EPHA Pathway antibodies  EphrinA-EPHA Pathway Diagram

Diseases associated with anti-EPHA6 antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >2 publications with EPHA6 and Necrosis
 Inflammation Antibodies  >2 publications with EPHA6 and Inflammation
 Mental Disorders Antibodies  >2 publications with EPHA6 and Mental Disorders
 Dementia Antibodies  >1 publications with EPHA6 and Dementia
 Learning Disorders Antibodies  >1 publications with EPHA6 and Learning Disorders
 Congenital Abnormalities Antibodies  >1 publications with EPHA6 and Congenital Abnormalities
 Disease Models, Animal Antibodies  >1 publications with EPHA6 and Disease Models, Animal

Organs/Tissues associated with anti-EPHA6 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >13 publications with EPHA6 and Brain
 Kidney Antibodies  >1 publications with EPHA6 and Kidney
 Prostate Antibodies  >1 publications with EPHA6 and Prostate
 Testis Antibodies  >1 publications with EPHA6 and Testis
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