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TMBIM6 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS245094

MBS245094 is an antibody targeting TMBIM6. Also known as Mouse Monoclonal [clone 20F430] (IgG2b) to Human TMBIM6 / Bax Inhibitor 1. Reactive in Human, Mouse, Rat. Host: Mouse. More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Product Overview

Product Name
TMBIM6 / Bax Inhibitor 1, Monoclonal Antibody
Full Product Name
Mouse Monoclonal [clone 20F430] (IgG2b) to Human TMBIM6 / Bax Inhibitor 1
Product Gene Name
Product Synonym Names
Anti-TMBIM6 / Bax Inhibitor 1 Antibody (clone 20F430) IHC-plus; TMBIM6; BI1; Bax inhibitor 1; BAXI1; BI-1; TEGT; Human TMBIM6; Bax Inhibitor 1
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
20F430
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS, 0.2% gelatin, 0.05% sodium azide.
Purity/Purification
Protein G Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
A mixture of three synthetic peptides corresponding to the N-terminal, internal and C-terminal regions of human Bax Inhibitor 1. Epitope mapping indicates that the antibody recognizes an epitope in the N-terminal region of Bi-1.
Preparation and Storage
+4 degree C or -20 degree C, Avoid repeated freezing and thawing.
Molecular Weight
32,711 Da
OMIM
600748
3D Structure
ModBase 3D Structure for P55061
Target Species
Human
Immunogen Description
Synthetic peptide from human TMBIM6 / Bax Inhibitor 1.
Immunogen Type
Synthetic peptide
Immunogen
TMBIM6 / Bax Inhibitor 1 antibody was raised against synthetic peptide from human TMBIM6 / Bax Inhibitor 1.
Applications Tested/Suitable for anti-TMBIM6 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-TMBIM6 antibody
IHC-P (5 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-TMBIM6 antibody

Anti-TMBIM6 / Bax Inhibitor 1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Mouse Anti-TMBIM6 Monoclonal Antibody – Cat# MBS245094

Other Notes

Small volumes of anti-TMBIM6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TMBIM6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
bax inhibitor 1 isoform 1
NCBI Official Synonym Full Names
transmembrane BAX inhibitor motif containing 6
NCBI Official Symbol
TMBIM6
NCBI Official Synonym Symbols
BI-1; TEGT; BAXI1
UniProt Protein Name
Bax inhibitor 1
UniProt Synonym Protein Names
Testis-enhanced gene transcript protein; Transmembrane BAX inhibitor motif-containing protein 6
UniProt Gene Name
TMBIM6
UniProt Synonym Gene Names
BI1; TEGT; BI-1
UniProt Entry Name
BI1_HUMAN
NCBI Protein Information
bax inhibitor 1; testis enhanced gene transcript; testis-enhanced gene transcript protein; transmembrane BAX inhibitor motif-containing protein 6

UniProt Comments for TMBIM6

TMBIM6: Suppressor of apoptosis. Modulates unfolded protein response signaling. Modulate ER calcium homeostasis by acting as a calcium-leak channel. Belongs to the BI1 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 12q13.12

Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to plasma membrane; nucleus

Molecular Function: enzyme binding

Biological Process: endoplasmic reticulum calcium ion homeostasis; negative regulation of mRNA cleavage; negative regulation of protein binding; response to unfolded protein
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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