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DEC-205 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS245310

LY75/CD205/DEC-205 is an integral membrane protein homologous to the macrophage mannose receptor and functions as an antigen-uptake receptor on dendritic cells. DEC-205 is rapidly taken up by means of coated pits and vesicles and is delivered to a… More details

$650 / 0.05 mL +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
DEC-205 / CD205 / LY75, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human DEC-205 / CD205 / LY75
Product Gene Name
Product Synonym Names
Anti-DEC-205 / CD205 / LY75 Antibody (C-Terminus) IHC-plus; LY75; CD205; CLEC13B; CD205 antigen; LY-75; Lymphocyte antigen 75; DEC-205; gp200-MR6; Human DEC-205; CD205; LY75
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
20 mM Tris-HCl, pH 8.0, 20 mg/ml BSA, 0.05% sodium azide
Purity/Purification
Purified
Concentration
1.2 mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C. Aliquot to avoid freeze/thaw cycles.
Molecular Weight
26,183 Da
OMIM
604524
3D Structure
ModBase 3D Structure for O60449
Target Species
Human
Immunogen Description
Peptide derived from C-terminal sequence of human CD205.
Immunogen
DEC-205 / CD205 / LY75 antibody was raised against peptide derived from C-terminal sequence of human CD205.
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-DEC-205 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-DEC-205 antibody
IHC-P (10 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-DEC-205 antibody

Anti-LY75 / DEC-205 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-DEC-205 Polyclonal Antibody – Cat# MBS245310

Other Notes

Small volumes of anti-DEC-205 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DEC-205 purchase

MBS245310 is an antibody targeting DEC-205. Also known as Rabbit Polyclonal to Human DEC-205 / CD205 / LY75. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DEC-205. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
lymphocyte antigen 75
NCBI Official Synonym Full Names
lymphocyte antigen 75
NCBI Official Symbol
LY75
NCBI Official Synonym Symbols
CD205; LY-75; CLEC13B; DEC-205; GP200-MR6
UniProt Protein Name
Lymphocyte antigen 75
UniProt Synonym Protein Names
C-type lectin domain family 13 member B; DEC-205; gp200-MR6; CD_antigen: CD205
UniProt Gene Name
LY75
UniProt Synonym Gene Names
CD205; CLEC13B; Ly-75
UniProt Entry Name
LY75_HUMAN
NCBI Protein Information
lymphocyte antigen 75; C-type lectin domain family 13 member B

UniProt Comments for DEC-205

LY75: Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen- processing compartment. Causes reduced proliferation of B-lymphocytes. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q24

Cellular Component: integral to plasma membrane

Molecular Function: receptor activity; carbohydrate binding

Biological Process: immune response; endocytosis; inflammatory response
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Research Articles on DEC-205

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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