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S100A10 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS245409

S100A10/p11 belongs to the S-100 calcium binding protein family, although it has had crucial amino acid substitutions and deletions that render it incapable of binding calcium. p11 forms a heterotetrameric complex with annexin II. p11 functions as an… More details

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Product Overview

Online Datasheet in PDF
Product Name
S100A10, Monoclonal Antibody
Full Product Name
Mouse Monoclonal (IgG1) to Human S100A10
Product Gene Name
Product Synonym Names
Anti-S100A10 Antibody IHC-plus; S100A10; 42C; ANX2LG; Calpactin-1 light chain; Calpactin I light chain; CLP11; p11; p10; p10 protein; Protein S100-A10; ANX2L; Ca[1]; CAL1L; Cellular ligand of annexin II; gp11; Human S100A10
Clonality
Monoclonal
Isotype
IgG1
Host
Mouse
Species Reactivity
Human
Form/Format
PBS, pH 7.4, 0.03% sodium azide.
Purity/Purification
Protein A Purified
Specificity
Ni-NTA purified truncated recombinant P11 expressed in E Coli strain BL21 (DE3)
Molecular Weight
11,203 Da
OMIM
114085
3D Structure
ModBase 3D Structure for P60903
Target Species
Human
Immunogen Description
Recombinant Human S100A10.
Immunogen Type
Recombinant protein
Immunogen
S100A10 antibody was raised against recombinant Human S100A10.
Applications Tested/Suitable for anti-S100A10 antibody
Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
Application Notes for anti-S100A10 antibody
ELISA (1:10000), IF (1:100 - 1:500), IHC-P (1:200), WB
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-S100A10 antibody

Anti-S100A10 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Mouse Anti-S100A10 Monoclonal Antibody – Cat# MBS245409

Immunohistochemistry (IHC) of anti-S100A10 antibody

Anti-S100A10 antibody IHC of human nerve and ganglion cell. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Mouse Anti-S100A10 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS245409

Western Blot (WB) of anti-S100A10 antibody

 
Mouse Anti-S100A10 Monoclonal Antibody, Western Blot (WB) – Cat# MBS245409

Other Notes

Small volumes of anti-S100A10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for S100A10 purchase

MBS245409 is an antibody targeting S100A10. Also known as Mouse Monoclonal (IgG1) to Human S100A10. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for S100A10. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein S100-A10
NCBI Official Synonym Full Names
S100 calcium binding protein A10
NCBI Official Symbol
S100A10
NCBI Official Synonym Symbols
42C; P11; p10; GP11; ANX2L; CAL1L; CLP11; Ca[1]; ANX2LG
UniProt Protein Name
Protein S100-A10
UniProt Synonym Protein Names
Calpactin I light chain; Calpactin-1 light chain; Cellular ligand of annexin II; S100 calcium-binding protein A10; p10 protein; p11
Protein Family
UniProt Gene Name
S100A10
UniProt Synonym Gene Names
ANX2LG; CAL1L; CLP11
UniProt Entry Name
S10AA_HUMAN
NCBI Protein Information
protein S100-A10; calpactin I light chain; calpactin-1 light chain; cellular ligand of annexin II; annexin II tetramer (AIIt) p11 subunit; annexin II ligand, calpactin I, light polypeptide; S100 calcium binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)); S100 calcium-binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11))

NCBI Summary for S100A10

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis. [provided by RefSeq, Jul 2008]
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UniProt Comments for S100A10

S100A10: Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine- specific kinase. Heterotetramer containing 2 light chains of S100A10/p11 and 2 heavy chains of ANXA2/p36. Interacts with SCN10A. Belongs to the S-100 family.

Protein type: Calcium-binding

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: extrinsic to plasma membrane; lipid raft

Molecular Function: protein binding; protein homodimerization activity; calcium ion binding; lipid binding

Biological Process: positive regulation of focal adhesion formation; positive regulation of stress fiber formation; protein heterotetramerization; positive regulation of binding; lipid raft formation; membrane budding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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