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MUC5AC Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS245642

MUC5AC has been isolated from airway secretions. It is found in the protective film of mucus coating the mucosal surfaces of the respiratory tract and the normal gastrointestinal tissues. Mucins are also expressed at low levels in human fetal gut. MUC5AC is… More details

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Product Overview

Product Name
MUC5AC, Monoclonal Antibody
Full Product Name
Mouse Monoclonal [clone 1-13M1] (IgG1) to Human MUC5AC
Product Gene Name
Product Synonym Names
Anti-MUC5AC Antibody (clone 1-13M1) IHC-plus; MUC5AC; Gastric mucin; Major airway glycoprotein; Muc5/5ac; Mucin-5AC; LeB; Lewis B blood group antigen; Tracheobronchial mucin; TBM; MUC-5AC; MUC5; Human MUC5AC
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1-13M1
Host
Mouse
Species Reactivity
Human
Form/Format
PBS, 0.05% sodium azide
Purity/Purification
Purified
Concentration
0.1 mg/ml (lot specific)
Specificity
1-13M1 reacts with peptide core of gastric mucin (MUC5AC).
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
Molecular Weight
526,608 Da
OMIM
158373
3D Structure
ModBase 3D Structure for P98088
Target Species
Human
Immunogen Description
Mucin isolated from an ovarian cyst fluid (pure endocervical type according to the Fenoglio's classification).
Immunogen
MUC5AC antibody was raised against mucin isolated from an ovarian cyst fluid (pure endocervical type according to the Fenoglio's classification).
Applications Tested/Suitable for anti-MUC5AC antibody
Immunohistochemistry (IHC - Paraffin; IHC - Frozen), Western Blot (WB), ELISA (EIA)
Application Notes for anti-MUC5AC antibody
ELISA, IHC-Fr, IHC-P (1:100), WB
Usage: Immunohistochemistry on cultured cells. Immunochemistry on frozen ethanol fixed section. Immunochemistry on paraffin section: a protease pretreatment is recommended. monoclonal antibody cross-reacts with mucin of different animal species after period date pretreatment. Western Blot: strongly positive without mercaptoethanol pretreatment of mucin solution. ELISA or IRMA in combination with the 9-13M1 monoclonal antibody or the mixture of anti-M1 MoAbs.

Immunohistochemistry (IHC) of anti-MUC5AC antibody

Anti-MUC5AC antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Mouse Anti-MUC5AC Monoclonal Antibody – Cat# MBS245642

Other Notes

Small volumes of anti-MUC5AC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MUC5AC purchase

MBS245642 is an antibody targeting MUC5AC. Also known as Mouse Monoclonal [clone 1-13M1] (IgG1) to Human MUC5AC. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for MUC5AC. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Mucin-5AC
NCBI Official Synonym Full Names
mucin 5AC, oligomeric mucus/gel-forming
NCBI Official Symbol
MUC5AC
NCBI Official Synonym Symbols
TBM; leB; MUC5
UniProt Protein Name
Mucin-5AC
UniProt Synonym Protein Names
Gastric mucin; Lewis B blood group antigen; LeB; Major airway glycoprotein; Mucin-5 subtype AC, tracheobronchial; Tracheobronchial mucin; TBM
Protein Family
UniProt Gene Name
MUC5AC
UniProt Synonym Gene Names
MUC5; MUC-5AC; LeB; TBM
UniProt Entry Name
MUC5A_HUMAN
NCBI Protein Information
mucin-5AC; mucin 5AC, oligomeric mucus/gel-forming; gastric mucin; tracheobronchial mucin; major airway glycoprotein; lewis B blood group antigen; mucin-5 subtype AC, tracheobronchial; mucin 5AC, oligomeric mucus/gel-forming pseudogene; mucin 5, subtypes A and C, tracheobronchial/gastric

UniProt Comments for MUC5AC

MUC5AC iso1:

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: Golgi lumen; fibril

Molecular Function: extracellular matrix structural constituent

Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; O-glycan processing; fibril organization and biogenesis; post-translational protein modification
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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