Fibroblast Growth Factor 7 (FGF7) ELISA Kit for Rabbit

Name: Rabbit FGF7 ELISA Kit; Fibroblast Growth Factor 7; MyBioSource
Brand: MyBioSource
SKU: MBS024573
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS024573

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of FGF7 (hereafter termed this analyte) in undiluted original Rabbit serum, plasma and tissue homogenate… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Fibroblast Growth Factor 7 (FGF7), ELISA Kit

Full Product Name

Rabbit Fibroblast Growth Factor 7 ELISA Kit

Product Gene Name

FGF7 elisa kit

Species Reactivity

Rabbit

Assay Type

Sandwich

Samples

Serum, Plasma and Tissue Homogenate

Detection Range

6.25 pg/ml - 200 pg/ml.

Sensitivity

1.0 pg/ml.

Specificity

No significant cross-reactivity or interference between this analyte and analogues is observed.

Preparation and Storage

Store all reagents at 2-8 degree C

Intra-assay Precision

Intra-assay CV (%) is less than 15%.

Molecular Weight

22,509 Da

Chromosome Location

Chromosome: 15; NC_000015.9 (49715375..49779523). Location: 15q21.2

OMIM

148180

3D Structure

ModBase 3D Structure for P21781

Inter-assay

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Other Notes

Small volumes of FGF7 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FGF7 purchase

MBS024573 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Fibroblast Growth Factor 7 (FGF7) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FGF7. The ELISA analytical biochemical technique of the MBS024573 kit is based on FGF7 antibody-FGF7 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FGF7 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FGF7. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for FGF7. It may not necessarily be applicable to this product.

NCBI GI #

4503705

NCBI GeneID

2252

NCBI Accession #

NP_002000.1

UniProt Primary Accession #

P21781

UniProt Related Accession #

P21781

GenBank Nucleotide #

NM_002009.3

NCBI Official Full Name

fibroblast growth factor 7

NCBI Official Synonym Full Names

fibroblast growth factor 7

NCBI Official Symbol

FGF7

NCBI Official Synonym Symbols

KGF; HBGF-7

UniProt Protein Name

Fibroblast growth factor 7

UniProt Synonym Protein Names

Heparin-binding growth factor 7; HBGF-7; Keratinocyte growth factor

Protein Family

Fibroblast growth factor

UniProt Gene Name

FGF7

UniProt Synonym Gene Names

KGF; FGF-7; HBGF-7

UniProt Entry Name

FGF7_HUMAN

NCBI Protein Information

fibroblast growth factor 7; FGF-7; keratinocyte growth factor; heparin-binding growth factor 7

NCBI Summary for FGF7

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis. [provided by RefSeq, Jul 2008]

UniProt Comments for FGF7

FGF7: Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation. Belongs to the heparin-binding growth factors family.

Protein type: Secreted; Cytokine; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 15q21.2

Cellular Component: Golgi apparatus; extracellular region

Molecular Function: heparin binding; protein binding; growth factor activity; fibroblast growth factor receptor binding; chemoattractant activity

Biological Process: positive regulation of keratinocyte migration; epidermal growth factor receptor signaling pathway; epidermis development; phosphoinositide-mediated signaling; hair follicle morphogenesis; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; mesenchymal cell proliferation; signal transduction; positive regulation of peptidyl-tyrosine phosphorylation; positive chemotaxis; positive regulation of cell division; positive regulation of cell proliferation; actin cytoskeleton reorganization; insulin receptor signaling pathway; response to wounding; innate immune response; positive regulation of epithelial cell proliferation

Research Articles on FGF7

1. Increased KGF expression promotes fibroblast activation in a double paracrine manner resulting in cutaneous fibrosis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with FGF7 elisa kit

Reference Product	PubMed Publications
FGFR2 elisa kit	>250 publications with FGF7 and FGFR2
FGF1 elisa kit	>90 publications with FGF7 and FGF1
EGF elisa kit	>69 publications with FGF7 and EGF
FGFR1 elisa kit	>60 publications with FGF7 and FGFR1
FGFR3 elisa kit	>27 publications with FGF7 and FGFR3
FGF4 elisa kit	>21 publications with FGF7 and FGF4
FGFR4 elisa kit	>18 publications with FGF7 and FGFR4
FGF6 elisa kit	>10 publications with FGF7 and FGF6
FGF23 elisa kit	>6 publications with FGF7 and FGF23
FGFBP1 elisa kit	>2 publications with FGF7 and FGFBP1

Pathways associated with FGF7 elisa kit

Products by Pathway	Pathway Diagram
Activated Point Mutants Of FGFR2 Pathway antibodies	Activated Point Mutants Of FGFR2 Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Constitutive PI3K/AKT Signaling In Cancer Pathway antibodies	Constitutive PI3K/AKT Signaling In Cancer Pathway Diagram
DAP12 Interactions Pathway antibodies	DAP12 Interactions Pathway Diagram
DAP12 Signaling Pathway antibodies	DAP12 Signaling Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Downstream Signaling Events Of B Cell Receptor (BCR) Pathway antibodies	Downstream Signaling Events Of B Cell Receptor (BCR) Pathway Diagram
Downstream Signal Transduction Pathway antibodies	Downstream Signal Transduction Pathway Diagram
Downstream Signaling Of Activated FGFR Pathway antibodies	Downstream Signaling Of Activated FGFR Pathway Diagram
FGFR Ligand Binding And Activation Pathway antibodies	FGFR Ligand Binding And Activation Pathway Diagram

Diseases associated with FGF7 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>169 publications with FGF7 and Neoplasms
Carcinoma Antibodies	>71 publications with FGF7 and Carcinoma
Hyperplasia Antibodies	>65 publications with FGF7 and Hyperplasia
Lung Injury Antibodies	>62 publications with FGF7 and Lung Injury
Lung Diseases Antibodies	>59 publications with FGF7 and Lung Diseases
Inflammation Antibodies	>45 publications with FGF7 and Inflammation
Fibrosis Antibodies	>36 publications with FGF7 and Fibrosis
Necrosis Antibodies	>33 publications with FGF7 and Necrosis
Prostatic Hyperplasia Antibodies	>27 publications with FGF7 and Prostatic Hyperplasia
Breast Neoplasms Antibodies	>25 publications with FGF7 and Breast Neoplasms

Organs/Tissues associated with FGF7 elisa kit

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>168 publications with FGF7 and Lung
Skin Antibodies	>157 publications with FGF7 and Skin
Embryonic Tissue Antibodies	>110 publications with FGF7 and Embryonic Tissue
Prostate Antibodies	>71 publications with FGF7 and Prostate
Bone Antibodies	>67 publications with FGF7 and Bone
Intestine Antibodies	>67 publications with FGF7 and Intestine
Vascular Antibodies	>48 publications with FGF7 and Vascular
Kidney Antibodies	>41 publications with FGF7 and Kidney
Muscle Antibodies	>37 publications with FGF7 and Muscle
Liver Antibodies	>34 publications with FGF7 and Liver