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PBX3 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS245763

MBS245763 is an antibody targeting PBX3. Also known as Mouse Monoclonal [clone 1A11] (IgG2a,k) to Human PBX3. Reactive in Human. Host: Mouse. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PBX3, Monoclonal Antibody
Full Product Name
Mouse Monoclonal [clone 1A11] (IgG2a,k) to Human PBX3
Product Gene Name
Product Synonym Names
Anti-PBX3 Antibody (clone 1A11) IHC-plus; PBX3; Pre-B-cell leukemia homeobox 3; Homeobox protein PBX3; Human PBX3
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
1A11
Host
Mouse
Species Reactivity
Human
Form/Format
PBS, pH 7.2. Sourced in Ascites.
Purity/Purification
Protein A Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human Pbx3
Preparation and Storage
Store at -20 degree C or lower. Aliquot to avoid repeated freezing and thawing.
Molecular Weight
39,175 Da
OMIM
176312
3D Structure
ModBase 3D Structure for P40426
Target Species
Human
Immunogen Description
PBX3 (NP_006186, 342 a.a. ~ 435 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen
PBX3 antibody was raised against pBX3 (NP_006186, 342 a.a. ~ 435 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Applications Tested/Suitable for anti-PBX3 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-PBX3 antibody
ELISA, IHC-P (5 ug/ml), WB
Usage: Immunohistochemistry: Formalin-fixed paraffin-embedded sections. Sandwich ELISA: Recombinant protein. Western Blot: Cell lysate, Recombinant protein.

Immunohistochemistry (IHC) of anti-PBX3 antibody

Anti-PBX3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Mouse Anti-PBX3 Monoclonal Antibody – Cat# MBS245763

Western Blot (WB) of anti-PBX3 antibody

Western blot of PBX3 expression in K-562.
Mouse Anti-PBX3 Monoclonal Antibody, Western Blot (WB) – Cat# MBS245763

ELISA (EIA) of anti-PBX3 antibody

Detection limit for recombinant GST tagged PBX3 is approximately 1 ng/ml as a capture antibody.
Mouse Anti-PBX3 Monoclonal Antibody, ELISA (EIA) – Cat# MBS245763

Other Notes

Small volumes of anti-PBX3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PBX3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
pre-B-cell leukemia transcription factor 3 isoform 1
NCBI Official Synonym Full Names
pre-B-cell leukemia homeobox 3
NCBI Official Symbol
PBX3
UniProt Protein Name
Pre-B-cell leukemia transcription factor 3
UniProt Synonym Protein Names
Homeobox protein PBX3
UniProt Gene Name
PBX3
UniProt Entry Name
PBX3_HUMAN
NCBI Protein Information
pre-B-cell leukemia transcription factor 3; homeobox protein PBX3

UniProt Comments for PBX3

PBX3: Transcriptional activator that binds the sequence 5'- ATCAATCAA-3'. Belongs to the TALE/PBX homeobox family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 9q33.3

Cellular Component: transcription factor complex; nucleus

Molecular Function: sequence-specific DNA binding; transcription factor activity

Biological Process: dorsal spinal cord development; posterior compartment specification; anterior compartment specification; transcription, DNA-dependent; regulation of transcription, DNA-dependent; adult locomotory behavior; neuron development; neurological control of breathing; respiratory gaseous exchange
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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