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CMPK Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS245868

MBS245868 is an antibody targeting CMPK. Also known as Mouse Monoclonal [clone 1D7] (IgG2a,k) to Human CMPK / CMPK1. Reactive in Human. Host: Mouse. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CMPK / CMPK1, Monoclonal Antibody
Full Product Name
Mouse Monoclonal [clone 1D7] (IgG2a,k) to Human CMPK / CMPK1
Product Gene Name
anti-CMPK antibody
Product Synonym Gene Name
CMPK1
Product Synonym Names
Anti-CMPK / CMPK1 Antibody (clone 1D7) IHC-plus; CMPK1; CMPK; Deoxycytidylate kinase; Cytidine monophosphate kinase; RP11-511I2.1; UMP-CMPK; UMP/CMP kinase; Uridine monophosphate kinase; UCK; UMK; UMP-CMP kinase; UMP/CMPK; CMK; Cytidylate kinase; UMPK; Human CMPK; CMPK1
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
1D7
Host
Mouse
Species Reactivity
Human
Form/Format
PBS, pH 7.2. Sourced in Ascites.
Purity/Purification
Protein A Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human UMP/CMP kinase
Preparation and Storage
Aliquot and store at -20 degree C or -80 degree C. Avoid freeze-thaw cycles.
Molecular Weight
16,548 Da
OMIM
191710
3D Structure
ModBase 3D Structure for P30085
Target Species
Human
Immunogen Description
CMPK (AAH14961, 1 a.a. ~ 229 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen
CMPK / CMPK1 antibody was raised against cMPK (AAH14961, 1 a.a. ~ 229 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Product Categories/Family for anti-CMPK antibody

Family: Non-Protein Kinase; Subfamily: Adenylate kinase
Applications Tested/Suitable for anti-CMPK antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-CMPK antibody
ELISA, IHC-P (10 ug/ml), WB
Usage: Immunohistochemistry: Formalin-fixed paraffin-embedded sections. Western Blot: Cell lysate, Recombinant protein.

Immunohistochemistry (IHC) of anti-CMPK antibody

Anti-CMPK1 / CMPK antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Mouse Anti-CMPK Monoclonal Antibody – Cat# MBS245868

Western Blot (WB) of anti-CMPK antibody

CMPK monoclonal antibody, clone 1D7. Western blot of CMPK expression in K-562.
Mouse Anti-CMPK Monoclonal Antibody, Western Blot (WB) – Cat# MBS245868

Other Notes

Small volumes of anti-CMPK antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CMPK. It may not necessarily be applicable to this product.

NCBI GI #
7706497
NCBI GeneID
51727
NCBI Accession #
NP_057392.1
UniProt Primary Accession #
P30085
UniProt Secondary Accession #
Q53GB7; Q5SVZ0; Q96C07; Q9UBQ8; Q9UIA2; B4DPU7; E9PGI8
UniProt Related Accession #
P30085
GenBank Nucleotide #
NM_016308.2
NCBI Official Full Name
UMP-CMP kinase isoform a
NCBI Official Synonym Full Names
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
NCBI Official Symbol
CMPK1
NCBI Official Synonym Symbols
CK; CMK; UMK; CMPK; UMPK; UMP-CMPK
UniProt Protein Name
UMP-CMP kinase
UniProt Synonym Protein Names
Deoxycytidylate kinase; Nucleoside-diphosphate kinase; Uridine monophosphate/cytidine monophosphate kinase
Protein Family
UMP-CMP kinase
UniProt Gene Name
CMPK1
UniProt Entry Name
KCY_HUMAN
NCBI Protein Information
UMP-CMP kinase; CK; CMPK1; dCMP kinase; UMP/CMP kinase; cytidylate kinase; deoxycytidylate kinase; uridine monophosphate kinase; nucleoside-diphosphate kinase; uridine monophosphate/cytidine monophosphate kinase

NCBI Summary for CMPK

This gene encodes one of the enzymes required for cellular nucleic acid biosynthesis. This enzyme catalyzes the transfer of a phosphate group from ATP to CMP, UMP, or dCMP, to form the corresponding diphosphate nucleotide. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Feb 2012]
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UniProt Comments for CMPK

CMPK: Catalyzes specific phosphoryl transfer from ATP to UMP and CMP. Belongs to the adenylate kinase family.

Protein type: EC 2.7.4.6; EC 2.7.4.14; Kinase, other; Nucleotide Metabolism - pyrimidine

Chromosomal Location of Human Ortholog: 1p32

Cellular Component: nucleoplasm; cytoplasm; nucleolus; nucleus; cytosol

Molecular Function: uridine kinase activity; UMP kinase activity; nucleoside diphosphate kinase activity; cytidylate kinase activity; ATP binding

Biological Process: nucleobase, nucleoside and nucleotide metabolic process; nucleobase, nucleoside and nucleotide interconversion; UMP biosynthetic process; phthalate metabolic process; pyrimidine ribonucleotide biosynthetic process; nucleoside diphosphate phosphorylation; UDP biosynthetic process; ovulation cycle process; 'de novo' pyrimidine base biosynthetic process; CDP biosynthetic process; dUDP biosynthetic process; nucleoside triphosphate biosynthetic process; dCDP biosynthetic process
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Research Articles on CMPK

1. In particular, polymorphisms of the CMPK1 gene seem to provide important prognostic information

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CMPK antibody

 Reference Product  PubMed Publications
 DCTD antibody  >1 publications with CMPK and DCTD

Pathways associated with anti-CMPK antibody

 Products by Pathway  Pathway Diagram
 CMP Phosphorylation Pathway antibodies  CMP Phosphorylation Pathway Diagram
 CMP Phosphorylation Pathway antibodies  CMP Phosphorylation Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Nucleotides Pathway antibodies  Metabolism Of Nucleotides Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram
 Pyrimidine Ribonucleotide Biosynthesis, UMP => UDP/UTP,CDP/CTP Pathway antibodies  Pyrimidine Ribonucleotide Biosynthesis, UMP => UDP/UTP,CDP/CTP Pathway Diagram
 Pyrimidine Ribonucleotide Biosynthesis, UMP => UDP/UTP,CDP/CTP Pathway antibodies  Pyrimidine Ribonucleotide Biosynthesis, UMP => UDP/UTP,CDP/CTP Pathway Diagram
 Synthesis And Interconversion Of Nucleotide Di- And Triphosphates Pathway antibodies  Synthesis And Interconversion Of Nucleotide Di- And Triphosphates Pathway Diagram

Diseases associated with anti-CMPK antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >1 publications with CMPK and Necrosis

Organs/Tissues associated with anti-CMPK antibody

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >1 publications with CMPK and Eye
 Lung Antibodies  >1 publications with CMPK and Lung
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