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AK3 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS245957

MBS245957 is an antibody targeting AK3. Also known as Mouse Monoclonal [clone SJB3-36] (IgG1,k) to Human AK3 / Adenylate Kinase 3. Reactive in Human. Host: Mouse. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AK3 / Adenylate Kinase 3, Monoclonal Antibody
Full Product Name
Mouse Monoclonal [clone SJB3-36] (IgG1,k) to Human AK3 / Adenylate Kinase 3
Product Gene Name
Product Synonym Names
Anti-AK3 / Adenylate Kinase 3 Antibody (clone SJB3-36) IHC-plus; AK3; AK 3; AKL3L1; Adenylate kinase 3 alpha like; Adenylate kinase 3 like 1; Adenylate kinase 3; Adenylate kinase 6; AK3L1; AK6; AKL3L; FIX; Human AK3; Adenylate Kinase 3
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
SJB3-36
Host
Mouse
Species Reactivity
Human
Form/Format
PBS, pH 7.4, 0.1% sodium azide. Sourced in Ascites.
Purity/Purification
Protein G Purified
Concentration
1 mg/ml (lot specific)
Preparation and Storage
Long term: -20 degree C; Short term: +4 degree C; Avoid freeze-thaw cycles.
Molecular Weight
21,014 Da
OMIM
609290
3D Structure
ModBase 3D Structure for Q9UIJ7
Target Species
Human
Immunogen Description
Recombinant human AK3 (adenylate kinase isozyme 3) purified from E Coli.
Immunogen Type
Recombinant protein
Immunogen
AK3 / Adenylate Kinase 3 antibody was raised against recombinant human AK3 (adenylate kinase isozyme 3) purified from E Coli.
Applications Tested/Suitable for anti-AK3 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-AK3 antibody
ELISA, IHC-P (20 ug/ml), WB (1:500 - 1:2000)
Usage: The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since applications vary, each investigator should titrate the reagent to obtain optimal results. Recommended dilution range for Western blot analysi...

Immunohistochemistry (IHC) of anti-AK3 antibody

Anti-AK3 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.
Mouse Anti-AK3 Monoclonal Antibody – Cat# MBS245957

Western Blot (WB) of anti-AK3 antibody

The recombinant human AK isozymes (AK1(1), AK2(2) and AK3(3)) and mouse liver(4) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-AK3 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. 1: AK1; 2: AK2; 3: AK3; 4: Mouse liver.
Mouse Anti-AK3 Monoclonal Antibody, Western Blot (WB) – Cat# MBS245957

Other Notes

Small volumes of anti-AK3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for AK3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
GTP:AMP phosphotransferase AK3, mitochondrial isoform a
NCBI Official Synonym Full Names
adenylate kinase 3
NCBI Official Symbol
AK3
NCBI Official Synonym Symbols
AK6; FIX; AK3L1; AKL3L; AKL3L1
UniProt Protein Name
GTP:AMP phosphotransferase AK3, mitochondrial
UniProt Synonym Protein Names
Adenylate kinase 3; Adenylate kinase 3 alpha-like 1
UniProt Gene Name
AK3
UniProt Entry Name
KAD3_HUMAN
NCBI Protein Information
GTP:AMP phosphotransferase AK3, mitochondrial; adenylate kinase 3 alpha-like 1; GTP:AMP phosphotransferase, mitochondrial; adenylate kinase 6, adenylate kinase 3 like 1

NCBI Summary for AK3

The protein encoded by this gene is a GTP:ATP phosphotransferase that is found in the mitochondrial matrix. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Dec 2010]

UniProt Comments for AK3

AK3: is a GTP:ATP phosphotransferase that is found in the mitochondrial matrix. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Dec 2010]

Protein type: Transferase; EC 2.7.4.10; Nucleotide Metabolism - pyrimidine; Mitochondrial

Chromosomal Location of Human Ortholog: 9p24.1

Cellular Component: mitochondrion; mitochondrial matrix

Molecular Function: GTP binding; adenylate kinase activity; nucleoside triphosphate adenylate kinase activity; ATP binding

Biological Process: UTP metabolic process; ITP metabolic process; ADP biosynthetic process; blood coagulation; AMP metabolic process; phosphorylation; GTP metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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