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GAX Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS245969

MBS245969 is an antibody targeting GAX. Also known as Mouse Monoclonal [clone 6A5] (IgG1,k) to Human GAX / MEOX2. Reactive in Human, Mouse, Rat. Host: Mouse. More details

$650 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GAX / MEOX2, Monoclonal Antibody
Full Product Name
Mouse Monoclonal [clone 6A5] (IgG1,k) to Human GAX / MEOX2
Product Gene Name
Product Synonym Gene Name
MEOX2
Product Synonym Names
Anti-GAX / MEOX2 Antibody (clone 6A5) IHC-plus; MEOX2; MOX2; Mesenchyme homeobox 2; GAX; Homeobox protein MOX-2; Human GAX; MEOX2
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
6A5
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS, pH 7.4.
Purity/Purification
Protein A Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human Homeobox Protein Mox-2
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
Molecular Weight
33,594 Da
OMIM
600535
3D Structure
ModBase 3D Structure for P50222
Target Species
Human
Immunogen Description
MEOX2 (AAH17021, 1 a.a. ~ 304 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen
GAX / MEOX2 antibody was raised against mEOX2 (AAH17021, 1 a.a. ~ 304 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Applications Tested/Suitable for anti-GAX antibody
Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
Application Notes for anti-GAX antibody
ELISA, IF (10 ug/ml), IHC-P (5 ug/ml), WB (1:500 - 1:1000)
Usage: Immunohistochemistry: Formalin-fixed paraffin-embedded sections. Sandwich ELISA: Recombinant protein. Western blot using cell lysates and the recombinant protein used as the immunogen.

Immunohistochemistry (IHC) of anti-GAX antibody

Anti-MEOX2 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Mouse Anti-GAX Monoclonal Antibody – Cat# MBS245969

Immunofluorescence (IF) of anti-GAX antibody

Immunofluorescence of monoclonal antibody to MEOX2 on HeLa cell. [antibody concentration 10 ug/ml]
Mouse Anti-GAX Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS245969

Western Blot (WB) of anti-GAX antibody

MEOX2 monoclonal antibody clone 6A5. Western blot of MEOX2 expression in PC-12.
Mouse Anti-GAX Monoclonal Antibody, Western Blot (WB) – Cat# MBS245969

Western Blot (WB) of anti-GAX antibody

MEOX2 monoclonal antibody clone 6A5. Western blot of MEOX2 expression in NIH/3T3.
Mouse Anti-GAX Monoclonal Antibody, Western Blot (WB) – Cat# MBS245969

Western Blot (WB) of anti-GAX antibody

MEOX2 monoclonal antibody clone 6A5 Western blot of MEOX2 expression in HeLa.
Mouse Anti-GAX Monoclonal Antibody, Western Blot (WB) – Cat# MBS245969

ELISA (EIA) of anti-GAX antibody

Detection limit for recombinant GST tagged MEOX2 is approximately 0.3 ng/ml as a capture antibody.
Mouse Anti-GAX Monoclonal Antibody, ELISA (EIA) – Cat# MBS245969

Other Notes

Small volumes of anti-GAX antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GAX. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
homeobox protein MOX-2
NCBI Official Synonym Full Names
mesenchyme homeobox 2
NCBI Official Symbol
MEOX2
NCBI Official Synonym Symbols
GAX; MOX2
UniProt Protein Name
Homeobox protein MOX-2
UniProt Synonym Protein Names
Growth arrest-specific homeobox; Mesenchyme homeobox 2
UniProt Gene Name
MEOX2
UniProt Synonym Gene Names
GAX; MOX2
UniProt Entry Name
MEOX2_HUMAN
NCBI Protein Information
homeobox protein MOX-2; growth arrest-specific homeobox

NCBI Summary for GAX

This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse protein may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed in Alzheimer's disease. [provided by RefSeq, Jul 2008]
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UniProt Comments for GAX

MEOX2: Role in mesoderm induction and its earliest regional specification, somitogenesis, and myogenic and sclerotomal differentiation. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 7p22.1-p21.3

Cellular Component: cytoplasm; nuclear speck; nucleus

Molecular Function: protein binding; sequence-specific DNA binding; transcription factor activity

Biological Process: limb development; skeletal muscle development; somite specification; transcription, DNA-dependent; blood circulation; multicellular organismal development; positive regulation of transcription from RNA polymerase II promoter; angiogenesis; palate development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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