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HMX2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS245984

MBS245984 is an antibody targeting HMX2. Also known as Mouse Monoclonal [clone 1B10] (IgG2a,k) to Human HMX2. Reactive in Human. Host: Mouse. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
HMX2, Monoclonal Antibody
Full Product Name
Mouse Monoclonal [clone 1B10] (IgG2a,k) to Human HMX2
Product Gene Name
Product Synonym Names
Anti-HMX2 Antibody (clone 1B10) IHC-plus; HMX2; Homeobox protein HMX2; H6 family homeobox 2; Homeo box (H6 family) 2; Nkx5-2; H6L; Human HMX2
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
1B10
Host
Mouse
Species Reactivity
Human
Form/Format
PBS, pH 7.2
Purity/Purification
Protein A Purified
Concentration
0.3 mg/ml (lot specific)
Specificity
Human HMX2
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
Molecular Weight
29,598 Da
OMIM
600647
3D Structure
ModBase 3D Structure for A2RU54
Target Species
Human
Immunogen Description
HMX2 (NP_005510, 125 a.a. ~ 224 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen
HMX2 antibody was raised against hMX2 (NP_005510, 125 a.a. ~ 224 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Applications Tested/Suitable for anti-HMX2 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-HMX2 antibody
ELISA, IHC-P (5 ug/ml), WB
Usage: Immunohistochemistry: Formalin-fixed paraffin-embedded sections. Western Blot with the recombinant protein used as the immunogen.

Immunohistochemistry (IHC) of anti-HMX2 antibody

Anti-HMX2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Mouse Anti-HMX2 Monoclonal Antibody – Cat# MBS245984

Other Notes

Small volumes of anti-HMX2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HMX2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
homeobox protein HMX2
NCBI Official Synonym Full Names
H6 family homeobox 2
NCBI Official Symbol
HMX2
NCBI Official Synonym Symbols
H6L; Nkx5-2
UniProt Protein Name
Homeobox protein HMX2
UniProt Synonym Protein Names
Homeobox protein H6 family member 2
Protein Family
UniProt Gene Name
HMX2
UniProt Entry Name
HMX2_HUMAN
NCBI Protein Information
homeobox protein HMX2; homeo box (H6 family) 2; homeobox protein H6 family member 2

NCBI Summary for HMX2

The protein encoded by this gene is a member of the NKL homeobox family of transcription factors. Members in this family are of ancient origin and play an important role in organ development during embryogenesis. A related mouse protein plays a role in patterning of inner ear structures. In humans, variations in a region containing this gene have been associated with inner ear malformations, vestibular dysfunction, and hearing loss. [provided by RefSeq, Aug 2012]
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UniProt Comments for HMX2

HMX2: Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Belongs to the HMX homeobox family.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 10q26.13

Cellular Component: nucleus

Molecular Function: sequence-specific DNA binding

Biological Process: positive regulation of nuclear mRNA splicing, via spliceosome; inner ear morphogenesis; regulation of transcription, DNA-dependent; transcription, DNA-dependent; positive regulation of cell proliferation; brain development; cell differentiation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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