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SST Antibody – Rat Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS246055

MBS246055 is an antibody targeting SST. Also known as Rat Monoclonal [clone YC7] (IgG2b) to Human SST / Somatostatin. Reactive in Guinea pig, Human, Mouse, Pig, Rat. Host: Rat. More details

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Product Overview

Product Name
SST / Somatostatin, Monoclonal Antibody
Full Product Name
Rat Monoclonal [clone YC7] (IgG2b) to Human SST / Somatostatin
Product Gene Name
Product Synonym Names
Anti-SST / Somatostatin Antibody (clone YC7) IHC-plus; SST; Somatostatin-28; SMST; Somatostatin-14; Somatostatin; Human SST; Somatostatin
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
YC7
Host
Rat
Species Reactivity
Guinea pig, Human, Mouse, Pig, Rat
Form/Format
Tissue Culture Supernatant, 0.05% Thimerosal.
Specificity
Specific for somatostatin. A hormone involved in endocrine system regulation through interactions with pituitary growth hormone, thyroid stimulating hormone, and a number of hormones of the gastrointestinal tract. Somatostatin has active 14 amino acid and 28 amino acid forms, produced by alternate cleavage of the gene product. This antibody does not cross react with enkephalins, other endorphins, substance P, or CGRP. It partially Reacts with somatostatin fragments. The epitope recognized by this antibody lies within the 1-14 amino acid sequence of cyclic somatostatin
Preparation and Storage
+4 degree C or -20 degree C, Avoid repeated freezing and thawing.
Molecular Weight
12,736 Da
OMIM
182450
3D Structure
ModBase 3D Structure for P61278
Target Species
Human
Immunogen Description
Somatostatin conjugated to Thyroglobulin.
Immunogen
SST / Somatostatin antibody was raised against somatostatin conjugated to Thyroglobulin.

Product Categories/Family for anti-SST antibody

Applications Tested/Suitable for anti-SST antibody
Immunohistochemistry (IHC - Paraffin; IHC - Frozen)
Application Notes for anti-SST antibody
IHC-Fr, IHC-P (1:20)

Immunohistochemistry (IHC) of anti-SST antibody

Anti-Somatostatin antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:20.
Rat Anti-SST Monoclonal Antibody – Cat# MBS246055

Other Notes

Small volumes of anti-SST antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SST. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
somatostatin preproprotein
NCBI Official Synonym Full Names
somatostatin
NCBI Official Symbol
SST
NCBI Official Synonym Symbols
SMST
UniProt Protein Name
Somatostatin
UniProt Synonym Protein Names
Growth hormone release-inhibiting factorCleaved into the following 2 chains:Somatostatin-28; Somatostatin-14
Protein Family
UniProt Gene Name
SST
UniProt Entry Name
SMS_HUMAN
NCBI Protein Information
somatostatin; somatostatin-14; somatostatin-28; prepro-somatostatin; growth hormone release-inhibiting factor

NCBI Summary for SST

The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. [provided by RefSeq, Jul 2008]
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UniProt Comments for SST

SST: Somatostatin inhibits the release of somatotropin. Belongs to the somatostatin family.

Protein type: Secreted, signal peptide; Hormone; Secreted

Chromosomal Location of Human Ortholog: 3q28

Cellular Component: extracellular space; cell soma; extracellular region

Molecular Function: hormone activity

Biological Process: response to drug; induction of apoptosis by hormones; response to amino acid stimulus; regulation of cell migration; G-protein coupled receptor protein signaling pathway; synaptic transmission; negative regulation of cell proliferation; hyperosmotic response; cell surface receptor linked signal transduction; cell-cell signaling; response to steroid hormone stimulus; response to heat; digestion; response to nutrient
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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