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CDKL2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS246059

CDKL2 belongs to the CDKL subfamily. CDKL2 has been suggested to be important in learning and memory. Multiple variants of CDKL2 are generated by alternative splicing and intraexonal termination, resulting in diverse carboxy-terminal regulatory domains. Two… More details

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Technical Datasheet View PDF
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Product Overview

Product Name
CDKL2, Monoclonal Antibody
Full Product Name
Mouse Monoclonal [clone 1F6] (IgG1,k) to Human CDKL2
Product Gene Name
Product Synonym Names
Anti-CDKL2 Antibody (clone 1F6) IHC-plus; CDKL2; CDC2-related kinase; Cyclin-dependent kinase-like 2; Kkm; KKIAMRE; Protein kinase p56 KKIAMRE; p56 KKIAMRE protein kinase; p56; Human CDKL2
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
1F6
Host
Mouse
Species Reactivity
Human
Form/Format
PBS, pH 7.2
Purity/Purification
Protein A Purified
Preparation and Storage
Store at -20 degree C. Aliquot to avoid freeze/thaw cycles.
Molecular Weight
56,019 Da
OMIM
603442
3D Structure
ModBase 3D Structure for Q92772
Target Species
Human
Immunogen Description
CDKL2 (NP_003939, 394 a.a. ~ 493 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen Type
Recombinant protein
Immunogen
CDKL2 antibody was raised against cDKL2 (NP_003939, 394 a.a. ~ 493 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Applications Tested/Suitable for anti-CDKL2 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-CDKL2 antibody
ELISA, IHC-P (5 ug/ml), WB
Usage: Western blot performed with the recombinant protein used as the immunogen as the protein source.

Immunohistochemistry (IHC) of anti-CDKL2 antibody

Anti-CDKL2 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Mouse Anti-CDKL2 Monoclonal Antibody – Cat# MBS246059

Immunohistochemistry (IHC) of anti-CDKL2 antibody

Anti-CDKL2 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Mouse Anti-CDKL2 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS246059

Other Notes

Small volumes of anti-CDKL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CDKL2 purchase

MBS246059 is an antibody targeting CDKL2. Also known as Mouse Monoclonal [clone 1F6] (IgG1,k) to Human CDKL2. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CDKL2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cyclin-dependent kinase-like 2
NCBI Official Synonym Full Names
cyclin-dependent kinase-like 2 (CDC2-related kinase)
NCBI Official Symbol
CDKL2
NCBI Official Synonym Symbols
P56; KKIAMRE
UniProt Protein Name
Cyclin-dependent kinase-like 2
UniProt Synonym Protein Names
Protein kinase p56 KKIAMRE; Serine/threonine-protein kinase KKIAMRE
UniProt Gene Name
CDKL2
UniProt Entry Name
CDKL2_HUMAN
NCBI Protein Information
cyclin-dependent kinase-like 2; CDC2-related kinase; p56 KKIAMRE protein kinase; protein kinase p56 KKIAMRE; serine/threonine protein kinase KKIAMRE; serine/threonine-protein kinase KKIAMRE

NCBI Summary for CDKL2

This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the cytoplasm, with lower levels in the nucleus. [provided by RefSeq, Jul 2008]

UniProt Comments for CDKL2

CDKL2: a protein kinase of the CDKL family. Accumulates primarily in the cytoplasm, with a lower level in the nucleus.

Protein type: Cell cycle regulation; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.22; Protein kinase, CMGC; Kinase, protein; CMGC group; CDKL family

Chromosomal Location of Human Ortholog: 4q21.1

Cellular Component: nucleoplasm; centrosome; cytoplasm; nucleus

Molecular Function: cyclin-dependent protein kinase activity; ATP binding; protein kinase activity

Biological Process: regulation of cell cycle; signal transduction; sex differentiation; protein amino acid phosphorylation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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