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CGGBP1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS246143

MBS246143 is an antibody targeting CGGBP1. Also known as Mouse Monoclonal [clone 1D11] (IgG1,k) to Human CGGBP1. Reactive in Human. Host: Mouse. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CGGBP1, Monoclonal Antibody
Full Product Name
Mouse Monoclonal [clone 1D11] (IgG1,k) to Human CGGBP1
Product Gene Name
Product Synonym Names
Anti-CGGBP1 Antibody (clone 1D11) IHC-plus; CGGBP1; 20 kDa CGG-binding protein; CGGBP; p20-CGGBP; p20-CGGBP DNA-binding protein; CGG-binding protein 1; p20-CGG binding protein; Human CGGBP1
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
1D11
Host
Mouse
Species Reactivity
Human
Form/Format
PBS, pH 7.2. Sourced in Ascites.
Purity/Purification
Protein A Purified
Preparation and Storage
Store at -20 degree C. Aliquot to avoid freeze/thaw cycles.
Molecular Weight
18,820 Da
OMIM
603363
3D Structure
ModBase 3D Structure for Q9UFW8
Target Species
Human
Immunogen Description
CGGBP1 (NP_003654, 58 a.a. ~ 168 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen Type
Recombinant protein
Immunogen
CGGBP1 antibody was raised against cGGBP1 (NP_003654, 58 a.a. ~ 168 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Applications Tested/Suitable for anti-CGGBP1 antibody
Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
Application Notes for anti-CGGBP1 antibody
ELISA, IF (10 ug/ml), IHC-P (5 ug/ml), WB
Usage: Western Blot (Cell lysate) - positive control K-562. Immunofluorescence (10 ug/ml) - positive control HeLa cells. Sandwich ELISA (Recombinant protein).

Immunohistochemistry (IHC) of anti-CGGBP1 antibody

Anti-CGGBP1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Mouse Anti-CGGBP1 Monoclonal Antibody – Cat# MBS246143

Immunofluorescence (IF) of anti-CGGBP1 antibody

Immunofluorescence of monoclonal antibody to CGGBP1 on HeLa cell (antibody concentration 10 ug/ml).
Mouse Anti-CGGBP1 Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS246143

Western Blot (WB) of anti-CGGBP1 antibody

CGGBP1 monoclonal antibody clone 1D11 Western blot of CGGBP1 expression in K-562.
Mouse Anti-CGGBP1 Monoclonal Antibody, Western Blot (WB) – Cat# MBS246143

ELISA (EIA) of anti-CGGBP1 antibody

Detection limit for recombinant GST tagged CGGBP1 is approximately 0.03 ng/ml as a capture antibody.
Mouse Anti-CGGBP1 Monoclonal Antibody, ELISA (EIA) – Cat# MBS246143

Other Notes

Small volumes of anti-CGGBP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CGGBP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
CGG triplet repeat-binding protein 1
NCBI Official Synonym Full Names
CGG triplet repeat binding protein 1
NCBI Official Symbol
CGGBP1
NCBI Official Synonym Symbols
CGGBP; p20-CGGBP
UniProt Protein Name
CGG triplet repeat-binding protein 1
UniProt Synonym Protein Names
20 kDa CGG-binding protein; p20-CGGBP DNA-binding protein
UniProt Gene Name
CGGBP1
UniProt Synonym Gene Names
CGGBP; CGG-binding protein 1
UniProt Entry Name
CGBP1_HUMAN
NCBI Protein Information
CGG triplet repeat-binding protein 1; CGG-binding protein 1; p20-CGG binding protein; 20 kDa CGG-binding protein; p20-CGGBP DNA-binding protein

NCBI Summary for CGGBP1

CGGBP1 influences expression of the FMR1 gene (MIM 309550), which is associated with the fragile X mental retardation syndrome (MIM 300624), by specifically interacting with the 5-prime (CGG)n-3-prime repeat in its 5-prime UTR.[supplied by OMIM, Mar 2008]

UniProt Comments for CGGBP1

CGGBP1: Binds to nonmethylated 5'-d(CGG)(n)-3' trinucleotide repeats in the FMR1 promoter. May play a role in regulating FMR1 promoter.

Protein type: Transcription regulation

Chromosomal Location of Human Ortholog: 3p11.1

Cellular Component: nucleoplasm; nucleus

Molecular Function: double-stranded DNA binding

Biological Process: transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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