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BBOX1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS246333

MBS246333 is an antibody targeting BBOX1. Also known as Mouse Monoclonal [clone 6H3] (IgG1,k) to Human BBOX1 / BBOX. Reactive in Human. Host: Mouse. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
BBOX1 / BBOX, Monoclonal Antibody
Full Product Name
Mouse Monoclonal [clone 6H3] (IgG1,k) to Human BBOX1 / BBOX
Product Gene Name
Product Synonym Gene Name
BBOX
Product Synonym Names
Anti-BBOX1 / BBOX Antibody (clone 6H3) IHC-plus; BBOX1; BBH; G-BBH; Gamma-BBH; BBOX; Human BBOX1; BBOX
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
6H3
Host
Mouse
Species Reactivity
Human
Form/Format
PBS, pH 7.2
Purity/Purification
Protein A Purified
Preparation and Storage
Store at -20 degree C. Aliquot to avoid freeze/thaw cycles.
Molecular Weight
44,715 Da
OMIM
603312
3D Structure
ModBase 3D Structure for O75936
Target Species
Human
Immunogen Description
BBOX1 (NP_003977, 278 a.a. ~ 388 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen Type
Recombinant protein
Immunogen
BBOX1 / BBOX antibody was raised against bBOX1 (NP_003977, 278 a.a. ~ 388 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Applications Tested/Suitable for anti-BBOX1 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-BBOX1 antibody
ELISA, IHC-P (10 ug/ml), WB
Usage: Sandwich ELISA (Recombinant protein).

Immunohistochemistry (IHC) of anti-BBOX1 antibody

Anti-BBOX1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Mouse Anti-BBOX1 Monoclonal Antibody – Cat# MBS246333

ELISA (EIA) of anti-BBOX1 antibody

Detection limit for recombinant GST tagged BBOX1 is approximately 1 ng/ml as a capture antibody.
Mouse Anti-BBOX1 Monoclonal Antibody, ELISA (EIA) – Cat# MBS246333

Other Notes

Small volumes of anti-BBOX1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for BBOX1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
gamma-butyrobetaine dioxygenase
NCBI Official Synonym Full Names
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
NCBI Official Symbol
BBOX1
NCBI Official Synonym Symbols
BBH; BBOX; G-BBH; gamma-BBH
UniProt Protein Name
Gamma-butyrobetaine dioxygenase
UniProt Synonym Protein Names
Gamma-butyrobetaine hydroxylase; Gamma-BBH; Gamma-butyrobetaine,2-oxoglutarate dioxygenase
UniProt Gene Name
BBOX1
UniProt Synonym Gene Names
BBH; BBOX; Gamma-BBH
UniProt Entry Name
BODG_HUMAN
NCBI Protein Information
gamma-butyrobetaine dioxygenase; gamma-butyrobetaine hydroxylase; gamma-butyrobetaine,2-oxoglutarate dioxygenase 1

NCBI Summary for BBOX1

This gene encodes gamma butyrobetaine hydroxylase which catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthetic pathway. Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta-oxidation. [provided by RefSeq, Jul 2008]
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UniProt Comments for BBOX1

BBOX1: Catalyzes the formation of L-carnitine from gamma- butyrobetaine. Belongs to the gamma-BBH/TMLD family.

Protein type: EC 1.14.11.1; Amino Acid Metabolism - lysine degradation; Oxidoreductase

Chromosomal Location of Human Ortholog: 11p14.2

Cellular Component: mitochondrion; cytosol

Molecular Function: gamma-butyrobetaine dioxygenase activity; zinc ion binding; iron ion binding

Biological Process: carnitine biosynthetic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-BBOX1 antibody

 Reference Product  PubMed Publications
 ALDH9A1 antibody  >2 publications with BBOX1 and ALDH9A1
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