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AMPH Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS246351

MBS246351 is an antibody targeting AMPH. Also known as Mouse Monoclonal (IgG1,k) to Human AMPH / Amphiphysin. Reactive in Human, Mouse, Rat. Host: Mouse. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AMPH / Amphiphysin, Monoclonal Antibody
Full Product Name
Mouse Monoclonal (IgG1,k) to Human AMPH / Amphiphysin
Product Gene Name
Product Synonym Names
Anti-AMPH / Amphiphysin Antibody (aa1-347) IHC-plus; AMPH1; Amphiphysin; Amphiphysin I; Human AMPH; Amphiphysin
Clonality
Monoclonal
Isotype
IgG1,k
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Form/Format
HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol
Purity/Purification
Purified
Concentration
1 mg/ml (lot specific)
Preparation and Storage
Long term: -20 degree C; Short term: -20 degree C
Molecular Weight
71,929 Da
OMIM
600418
3D Structure
ModBase 3D Structure for P49418
Target Species
Human
Immunogen Description
Recombinant human GST-fragment protein (1-347AA) purified from E Coli.
Immunogen Type
Recombinant protein
Immunogen
AMPH / Amphiphysin antibody was raised against recombinant human GST-fragment protein (1-347AA) purified from E Coli.
Antigen Modification
aa1-347
Applications Tested/Suitable for anti-AMPH antibody
Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-AMPH antibody
ICC (1:100), IHC-P (1:200), IP, WB (1:2000)

Immunohistochemistry (IHC) of anti-AMPH antibody

Anti-Amphiphysin antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Mouse Anti-AMPH Monoclonal Antibody – Cat# MBS246351

Other Notes

Small volumes of anti-AMPH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for AMPH. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
amphiphysin isoform 1
NCBI Official Synonym Full Names
amphiphysin
NCBI Official Symbol
AMPH
NCBI Official Synonym Symbols
AMPH1
UniProt Protein Name
Amphiphysin
Protein Family
UniProt Gene Name
AMPH
UniProt Synonym Gene Names
AMPH1
UniProt Entry Name
AMPH_HUMAN
NCBI Protein Information
amphiphysin; amphiphysin I; amphiphysin (Stiff-Mann syndrome with breast cancer 128kD autoantigen)

NCBI Summary for AMPH

This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of this gene is found on chromosome 11.[provided by RefSeq, Nov 2010]
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UniProt Comments for AMPH

amphiphysin: May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 7p14-p13

Cellular Component: synaptic vesicle; synaptic vesicle membrane; cell junction; actin cytoskeleton

Molecular Function: protein binding; phospholipid binding

Biological Process: synaptic transmission; synaptic vesicle endocytosis; endocytosis; learning
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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