• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

PKP3 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS246360

MBS246360 is an antibody targeting PKP3. Also known as Mouse Monoclonal [clone 23E3/4] (IgG2b) to Human PKP3 / Plakophilin 3. Reactive in Dog, Human, Mouse. Host: Mouse. More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Product Name
PKP3 / Plakophilin 3, Monoclonal Antibody
Full Product Name
Mouse Monoclonal [clone 23E3/4] (IgG2b) to Human PKP3 / Plakophilin 3
Product Gene Name
Product Synonym Names
Anti-PKP3 / Plakophilin 3 Antibody (clone 23E3/4) IHC-plus; Plakophilin 3; Plakophilin-3; Plakophilin 3b; Human PKP3; Plakophilin 3
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
23E3/4
Host
Mouse
Species Reactivity
Dog, Human, Mouse
Form/Format
PBS containing 0.09% sodium azide
Purity/Purification
Purified
Concentration
1 mg/ml (lot specific)
Specificity
Reacts with an epitope located between residues 570-589 in human plakophilin-3.
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
Molecular Weight
88,655 Da
OMIM
605561
3D Structure
ModBase 3D Structure for Q9Y446
Target Species
Human
Immunogen Description
Synthetic peptide corresponding to amino acid residues 570-589 of human plakophilin-3 coupled to keyhole limpet hemocyanin via an additional cysteine residue at the N-terminus (CFTPQSRRLRELPLAADALTF)
Immunogen Type
Synthetic peptide
Applications Tested/Suitable for anti-PKP3 antibody
Immunohistochemistry (IHC - Paraffin; IHC - Frozen), Immunocytochemistry (ICC), Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-PKP3 antibody
ICC, IHC-Fr (1:25 - 1:200), IHC-P (20 ug/ml), IP, WB (1:100 - 1:1000)
Usage: Suitable for immunocytochemsitry on methanol- and paraformaldehyde-fixed cells. For optimal results, frozen tissues should be treated with 0.2% Triton-X 100 for 15 minutes prior to incubation with primary antibody.

Immunohistochemistry (IHC) of anti-PKP3 antibody

Anti-PKP3 / Plakophilin 3 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.
Mouse Anti-PKP3 Monoclonal Antibody – Cat# MBS246360

Other Notes

Small volumes of anti-PKP3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PKP3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
plakophilin-3 isoform PKP3a
NCBI Official Synonym Full Names
plakophilin 3
NCBI Official Symbol
PKP3
UniProt Protein Name
Plakophilin-3
Protein Family
UniProt Gene Name
PKP3
UniProt Entry Name
PKP3_HUMAN
NCBI Protein Information
plakophilin-3; plakophilin 3b

NCBI Summary for PKP3

This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]
Show more

UniProt Comments for PKP3

plakophilin 3: a novel armadillo-like protein present in nuclei and desmosomes of epithelial cells and dendritic reticular cells of lymphatic follicles.

Protein type: Cell adhesion

Chromosomal Location of Human Ortholog: 11p15

Cellular Component: desmosome; plasma membrane; intercellular junction; nucleus

Molecular Function: cell adhesion molecule binding

Biological Process: cell-cell adhesion
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000