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CD1B Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS246458

MBS246458 is an antibody targeting CD1B. Also known as Mouse Monoclonal [clone SN13/K5-1B8] (IgG1) to Human CD1B. Reactive in Human. Host: Mouse. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CD1B, Monoclonal Antibody
Full Product Name
Mouse Monoclonal [clone SN13/K5-1B8] (IgG1) to Human CD1B
Product Gene Name
Product Synonym Names
Anti-CD1B Antibody (clone SN13/K5-1B8) IHC-plus; CD1B; CD1; CD1b molecule; CD1b antigen; CD1B antigen; b polypeptide; Human CD1B
Clonality
Monoclonal
Isotype
IgG1
Clone Number
SN13/K5-1B8
Host
Mouse
Species Reactivity
Human
Form/Format
PBS, pH 7.2, <=0.09% sodium azide
Purity/Purification
Affinity Purified
Concentration
0.5 mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C, avoid repeated freeze thaw cycles.
Molecular Weight
30,740 Da
OMIM
188360
3D Structure
ModBase 3D Structure for P29016
Target Species
Human
Immunogen Description
Human CD1b
Applications Tested/Suitable for anti-CD1B antibody
Immunohistochemistry (IHC - Paraffin; IHC - Frozen), Flow Cytometry (FC/FACS)
Application Notes for anti-CD1B antibody
Flo, IHC-Fr, IHC-P (20 ug/ml)
Usage: This SN13 (SN13 K5-1B8) antibody has been tested by flow cytometric analysis of SN13 cells. This can be used at less than or equal to 1 ug per test. A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 1...

Immunohistochemistry (IHC) of anti-CD1B antibody

Anti-CD1B antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.
Mouse Anti-CD1B Monoclonal Antibody – Cat# MBS246458

Flow Cytometry (FC/FACS) of anti-CD1B antibody

Staining of Molt-4 cells with 0.5 ug of Purified Mouse IgG1, K isotype control (open histogram) or 0.5 ug of Purified anti-human CD1b (SN13) (colored histogram) followed by Biotin Anti-Mouse IgG and SAv-PE. Total viable cells were used for analysis.
Mouse Anti-CD1B Monoclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS246458

Other Notes

Small volumes of anti-CD1B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD1B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
T-cell surface glycoprotein CD1b
NCBI Official Synonym Full Names
CD1b molecule
NCBI Official Symbol
CD1B
NCBI Official Synonym Symbols
R1; CD1; CD1A
UniProt Protein Name
T-cell surface glycoprotein CD1b
UniProt Synonym Protein Names
CD_antigen: CD1b
UniProt Gene Name
CD1B
UniProt Entry Name
CD1B_HUMAN
NCBI Protein Information
T-cell surface glycoprotein CD1b; CD1B antigen, b polypeptide; cortical thymocyte antigen CD1B; differentiation antigen CD1-alpha-3

NCBI Summary for CD1B

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. [provided by RefSeq, Jul 2008]
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UniProt Comments for CD1B

CD1B: Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q23.1

Cellular Component: cell surface; lysosomal membrane; integral to membrane; plasma membrane; endosome membrane

Molecular Function: protein binding; beta-2-microglobulin binding; exogenous lipid antigen binding; endogenous lipid antigen binding

Biological Process: antigen processing and presentation, exogenous lipid antigen via MHC class Ib; immune response
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD1B antibody

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