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ADRM1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS246474

MBS246474 is an antibody targeting ADRM1. Also known as Mouse Monoclonal [clone 3D11] (IgG2b,k) to Human ADRM1 / Rpn13. Reactive in Human. Host: Mouse. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
ADRM1 / Rpn13, Monoclonal Antibody
Full Product Name
Mouse Monoclonal [clone 3D11] (IgG2b,k) to Human ADRM1 / Rpn13
Product Gene Name
Product Synonym Gene Name
Rpn13
Product Synonym Names
Anti-ADRM1 / Rpn13 Antibody (clone 3D11) IHC-plus; ADRM1; Adhesion regulating molecule 1; Adhesion-regulating molecule 1; ARM1; gp110; HRpn13; Rpn13 homolog; M(r) 110;000 surface antigen; ARM-1; Rpn13; Human ADRM1; Rpn13
Clonality
Monoclonal
Isotype
IgG2b,k
Clone Number
3D11
Host
Mouse
Species Reactivity
Human
Form/Format
PBS, pH 7.4.
Purity/Purification
Protein A Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human ADRM1
Preparation and Storage
Store at -20 degree C or lower. Aliquot to avoid repeated freezing and thawing.
Molecular Weight
42,153 Da
OMIM
610650
3D Structure
ModBase 3D Structure for Q16186
Target Species
Human
Immunogen Description
Full length recombinant human ADRM1.
Immunogen
ADRM1 / Rpn13 antibody was raised against full length recombinant human ADRM1.
Applications Tested/Suitable for anti-ADRM1 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-ADRM1 antibody
ELISA, IHC-P (10 ug/ml), WB (1:500 - 1:1000)
Usage: Sandwich ELISA: Recombinant protein. Western Blot: Cell lysate, Transfected lysate, Recombinant protein.

Immunohistochemistry (IHC) of anti-ADRM1 antibody

Anti-ADRM1 antibody IHC of human tonsil, germinal center. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Mouse Anti-ADRM1 Monoclonal Antibody – Cat# MBS246474

Western Blot (WB) of anti-ADRM1 antibody

Western blot of ADRM1 expression in transfected 293T cell line by ADRM1 monoclonal antibody (M02), clone 3D11.
Mouse Anti-ADRM1 Monoclonal Antibody, Western Blot (WB) – Cat# MBS246474

Western Blot (WB) of anti-ADRM1 antibody

ADRM1 monoclonal antibody (M02), clone 3D11. Western blot of ADRM1 expression in HeLa.
Mouse Anti-ADRM1 Monoclonal Antibody, Western Blot (WB) – Cat# MBS246474

ELISA (EIA) of anti-ADRM1 antibody

Detection limit for recombinant GST tagged ADRM1 is 0.03 ng/ml as a capture antibody.
Mouse Anti-ADRM1 Monoclonal Antibody, ELISA (EIA) – Cat# MBS246474

Other Notes

Small volumes of anti-ADRM1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ADRM1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
proteasomal ubiquitin receptor ADRM1 isoform 1
NCBI Official Synonym Full Names
adhesion regulating molecule 1
NCBI Official Symbol
ADRM1
NCBI Official Synonym Symbols
ARM1; ARM-1; GP110
UniProt Protein Name
Proteasomal ubiquitin receptor ADRM1
UniProt Synonym Protein Names
110 kDa cell membrane glycoprotein; Gp110; Adhesion-regulating molecule 1; ARM-1; Proteasome regulatory particle non-ATPase 13; hRpn13; Rpn13 homolog
UniProt Gene Name
ADRM1
UniProt Synonym Gene Names
GP110; Gp110; ARM-1; hRpn13
UniProt Entry Name
ADRM1_HUMAN
NCBI Protein Information
proteasomal ubiquitin receptor ADRM1; rpn13 homolog; M(r) 110,000 surface antigen; 110 kDa cell membrane glycoprotein; proteasome regulatory particle non-ATPase 13

NCBI Summary for ADRM1

This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
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UniProt Comments for ADRM1

ADRM1: Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity. Interacts with PSMD1, ubiquitin and UCHL5. Belongs to the ADRM1 family.

Protein type: Cell development/differentiation; Proteasome complex

Chromosomal Location of Human Ortholog: 20q13.33

Cellular Component: proteasome complex; nucleoplasm; membrane; integral to plasma membrane; cytoplasm; plasma membrane

Molecular Function: protein binding; protease binding

Biological Process: RNA elongation from RNA polymerase II promoter; proteasome assembly
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ADRM1 antibody

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