Mouse Anti-SFTPD Monoclonal Antibody – Cat# MBS246604

Anti-SFTPD / SP-D antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

SFTPD Antibody – Mouse Monoclonal

Name: SFTPD Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS246604
Price: 650 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS246604

MBS246604 is an antibody targeting SFTPD. Also known as Mouse Monoclonal [clone 2A10] (IgG1,k) to Human SFTPD / Surfactant Protein D. Reactive in Human. Host: Mouse. More details

$650 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SFTPD / Surfactant Protein D, Monoclonal Antibody

Full Product Name

Mouse Monoclonal [clone 2A10] (IgG1,k) to Human SFTPD / Surfactant Protein D

Product Gene Name

anti-SFTPD antibody

Product Synonym Names

Anti-SFTPD / Surfactant Protein D Antibody (clone 2A10) IHC-plus; SFTPD; COLEC7; Collectin 7; Collectin-7; Lung surfactant protein D; PSP-D; PSPD; SP-D; SFTP4; Surfactant protein D; Human SFTPD; Surfactant Protein D

Clonality

Monoclonal

Isotype

IgG1,k

Clone Number

2A10

Host

Mouse

Species Reactivity

Human

Form/Format

PBS, pH 7.2

Purity/Purification

Protein A Purified

Concentration

0.34 mg/ml (lot specific)

Specificity

Human SFTPD

Preparation and Storage

Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.

Molecular Weight

37,728 Da

OMIM

178635

3D Structure

ModBase 3D Structure for P35247

Target Species

Human

Immunogen Description

SFTPD (AAH22318.1, 21 a.a. ~ 376 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Immunogen

SFTPD / Surfactant Protein D antibody was raised against sFTPD (AAH22318.1, 21 a.a. ~ 376 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Applications Tested/Suitable for anti-SFTPD antibody

Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)

Application Notes for anti-SFTPD antibody

ELISA, IHC-P (5 ug/ml), WB
Usage: Immunohistochemistry: Formalin-fixed paraffin-embedded sections. Sandwich ELISA: Recombinant protein. Western Blot with the recombinant protein used as the immunogen.

Other Notes

Small volumes of anti-SFTPD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SFTPD. It may not necessarily be applicable to this product.

NCBI GI #

61699226

NCBI GeneID

6441

NCBI Accession #

NP_003010.4

UniProt Primary Accession #

P35247

UniProt Secondary Accession #

Q5T0M3; Q6FH08; Q86YK9; Q8TCD8; Q9UCJ2; Q9UCJ3

UniProt Related Accession #

P35247

GenBank Nucleotide #

NM_003019.4

NCBI Official Full Name

pulmonary surfactant-associated protein D

NCBI Official Synonym Full Names

surfactant protein D

NCBI Official Symbol

SFTPD

NCBI Official Synonym Symbols

SP-D; PSP-D; SFTP4; COLEC7

UniProt Protein Name

Pulmonary surfactant-associated protein D

UniProt Synonym Protein Names

Collectin-7; Lung surfactant protein D

Protein Family

Pulmonary surfactant-associated protein

UniProt Gene Name

SFTPD

UniProt Synonym Gene Names

COLEC7; PSPD; SFTP4; PSP-D; SP-D

UniProt Entry Name

SFTPD_HUMAN

NCBI Protein Information

pulmonary surfactant-associated protein D; collectin 7; collectin-7; lung surfactant protein D; pulmonary surfactant apoprotein; surfactant, pulmonary-associated protein D; surfactant-associated protein, pulmonary 4

NCBI Summary for SFTPD

The protein encoded by this gene is part of the innate immune response, protecting the lungs against inhaled microorganisms and chemicals. The encoded protein may also be involved in surfactant metabolism. [provided by RefSeq, Jul 2015]

UniProt Comments for SFTPD

SFTPD: Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. Belongs to the SFTPD family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 10q22.2-q23.1

Cellular Component: proteinaceous extracellular matrix; extracellular space; collagen; endocytic vesicle; lysosome; extracellular region

Molecular Function: protein binding; carbohydrate binding

Biological Process: receptor-mediated endocytosis; negative regulation of T cell proliferation; positive regulation of phagocytosis; defense response to bacterium; negative regulation of interleukin-2 biosynthetic process; innate immune response; respiratory gaseous exchange; macrophage chemotaxis; alveolus development; surfactant homeostasis; regulation of cytokine production

Research Articles on SFTPD

1. Both mRNA and protein levels of gp340 were significantly higher in patients with biofilm associated chronic rhinosinusitis (CRS) than those with CRS and no biofilm and controls.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SFTPD antibody

Reference Product	PubMed Publications
SFTPB antibody	>7 publications with SFTPD and SFTPB
SFTPC antibody	>5 publications with SFTPD and SFTPC
TLR4 antibody	>2 publications with SFTPD and TLR4

Pathways associated with anti-SFTPD antibody

Products by Pathway	Pathway Diagram
FOXA1 Transcription Factor Network Pathway antibodies	FOXA1 Transcription Factor Network Pathway Diagram
Phagosome Pathway antibodies	Phagosome Pathway Diagram
Phagosome Pathway antibodies	Phagosome Pathway Diagram
Regulation Of Retinoblastoma Protein Pathway antibodies	Regulation Of Retinoblastoma Protein Pathway Diagram

Diseases associated with anti-SFTPD antibody

Disease Name	Pubmed Publications
Lung Diseases Antibodies	>23 publications with SFTPD and Lung Diseases
Inflammation Antibodies	>15 publications with SFTPD and Inflammation
Lung Injury Antibodies	>8 publications with SFTPD and Lung Injury
Pneumonia Antibodies	>5 publications with SFTPD and Pneumonia
Respiratory Hypersensitivity Antibodies	>3 publications with SFTPD and Respiratory Hypersensitivity
Cardiovascular Diseases Antibodies	>3 publications with SFTPD and Cardiovascular Diseases
Lung Neoplasms Antibodies	>3 publications with SFTPD and Lung Neoplasms
Respiratory Distress Syndrome, Adult Antibodies	>2 publications with SFTPD and Respiratory Distress Syndrome, Adult
Disease Models, Animal Antibodies	>2 publications with SFTPD and Disease Models, Animal
Necrosis Antibodies	>2 publications with SFTPD and Necrosis

Organs/Tissues associated with anti-SFTPD antibody

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>33 publications with SFTPD and Lung
Connective Tissue Antibodies	>2 publications with SFTPD and Connective Tissue