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TTC1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS246660

MBS246660 is an antibody targeting TTC1. Also known as Mouse Monoclonal [clone 4E3] (IgG2b,k) to Human TTC1. Reactive in Human. Host: Mouse. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
TTC1, Monoclonal Antibody
Full Product Name
Mouse Monoclonal [clone 4E3] (IgG2b,k) to Human TTC1
Product Gene Name
Product Synonym Names
Anti-TTC1 Antibody (clone 4E3) IHC-plus; TTC1; TPR1; TPR repeat protein 1; Human TTC1
Clonality
Monoclonal
Isotype
IgG2b,k
Clone Number
4E3
Host
Mouse
Species Reactivity
Human
Form/Format
PBS, pH 7.2. Sourced in Ascites.
Purity/Purification
Protein A Purified
Preparation and Storage
Store at -20 degree C. Aliquot to avoid freeze/thaw cycles.
Molecular Weight
33,526 Da
OMIM
601963
3D Structure
ModBase 3D Structure for Q99614
Target Species
Human
Immunogen Description
TTC1 (NP_003305, 193 a.a. ~ 293 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen Type
Recombinant protein
Immunogen
TTC1 antibody was raised against tTC1 (NP_003305, 193 a.a. ~ 293 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Applications Tested/Suitable for anti-TTC1 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-TTC1 antibody
ELISA, IHC-P (5 ug/ml), WB
Usage: Western blot performed with the recombinant protein used as the immunogen.

Immunohistochemistry (IHC) of anti-TTC1 antibody

Anti-TTC1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Mouse Anti-TTC1 Monoclonal Antibody – Cat# MBS246660

Immunohistochemistry (IHC) of anti-TTC1 antibody

Anti-TTC1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Mouse Anti-TTC1 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS246660

Immunohistochemistry (IHC) of anti-TTC1 antibody

Anti-TTC1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Mouse Anti-TTC1 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS246660

Other Notes

Small volumes of anti-TTC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TTC1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tetratricopeptide repeat protein 1
NCBI Official Synonym Full Names
tetratricopeptide repeat domain 1
NCBI Official Symbol
TTC1
NCBI Official Synonym Symbols
TPR1
UniProt Protein Name
Tetratricopeptide repeat protein 1
UniProt Gene Name
TTC1
UniProt Synonym Gene Names
TPR1; TPR repeat protein 1
UniProt Entry Name
TTC1_HUMAN
NCBI Protein Information
tetratricopeptide repeat protein 1; TPR repeat protein 1

NCBI Summary for TTC1

This gene encodes a protein that belongs to the tetratrico peptide repeat superfamily of proteins. The encoded protein plays a role in protein-protein interactions, and binds to the Galpha subunit of G protein-coupled receptors to activate the Ras signaling pathway. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
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UniProt Comments for TTC1

TTC1: Interacts with the GAP domain of NF1.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 5q33.3

Cellular Component: peroxisomal membrane; cytoplasm

Molecular Function: protein binding; unfolded protein binding

Biological Process: protein folding

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TTC1 antibody

 Reference Product  PubMed Publications
 CRY2 antibody  >1 publications with TTC1 and CRY2

Diseases associated with anti-TTC1 antibody

 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >1 publications with TTC1 and Carcinoma
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