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TBC1D10A Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS246709

MBS246709 is an antibody targeting TBC1D10A. Also known as Goat Polyclonal to Human TBC1D10A. Reactive in Human, MonkeyPredicted Reactivity: Gibbon (at least 90% immunogen sequence identity). Host: Goat. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
TBC1D10A, Polyclonal Antibody
Full Product Name
Goat Polyclonal to Human TBC1D10A
Product Gene Name
Product Synonym Names
Anti-TBC1D10A Antibody (aa2-14) IHC-plus; TBC1D10A; AC004997.C22.2; DJ130H16.1; EBP50-PDZ interactor of 64 kD; DJ130H16.2; EPI64 protein; EBP50-PDX interactor of 64 kDa; EPI64; TBC1 domain family member 10A; TBC1 domain family; member 10A; Rab27A-GAP-alpha; TBC1 domain family; member 10; TBC1D10; Human TBC1D10A
Clonality
Polyclonal
Host
Goat
Species Reactivity
Human, Monkey
Predicted Reactivity: Gibbon (at least 90% immunogen sequence identity)
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human TBC1D10A.
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Molecular Weight
57,935 Da
OMIM
610020
3D Structure
ModBase 3D Structure for Q9BXI6
Target Species
Human
Immunogen Description
Synthetic peptide AKSNGENGPRAPA-C from positions 2-14 of human TBC1D10A (NP_114143.1). Percent identity by BLAST analysis: Human, Marmoset (100%); Gibbon (92%); Mouse, Rat, Bovine, Pig (85%).
Immunogen Type
Synthetic peptide
Immunogen
TBC1D10A antibody was raised against synthetic peptide AKSNGENGPRAPA-C from positions 2-14 of human TBC1D10A (NP_114143.1). Percent identity by BLAST analysis: Human, Marmoset (100%); Gibbon (92%); Mouse, Rat, Bovine, Pig (85%).
Antigen Modification
aa2-14
Applications Tested/Suitable for anti-TBC1D10A antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-TBC1D10A antibody
IHC-P (4.75 - 10 ug/ml)

Immunohistochemistry (IHC) of anti-TBC1D10A antibody

Anti-TBC1D10A antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4.75 ug/ml.
Goat Anti-TBC1D10A Polyclonal Antibody – Cat# MBS246709

Immunohistochemistry (IHC) of anti-TBC1D10A antibody

Anti-TBC1D10A antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4.75 ug/ml.
Goat Anti-TBC1D10A Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS246709

Other Notes

Small volumes of anti-TBC1D10A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TBC1D10A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
TBC1 domain family member 10A isoform 2
NCBI Official Synonym Full Names
TBC1 domain family, member 10A
NCBI Official Symbol
TBC1D10A
NCBI Official Synonym Symbols
EPI64; TBC1D10; dJ130H16.1; dJ130H16.2
UniProt Protein Name
TBC1 domain family member 10A
UniProt Synonym Protein Names
EBP50-PDX interactor of 64 kDa; EPI64 protein; Rab27A-GAP-alpha
Protein Family
UniProt Gene Name
TBC1D10A
UniProt Synonym Gene Names
EPI64; TBC1D10; EPI64 protein
UniProt Entry Name
TB10A_HUMAN
NCBI Protein Information
TBC1 domain family member 10A; rab27A-GAP-alpha; EBP50-PDZ interactor of 64 kD; EBP50-PDX interactor of 64 kDa

UniProt Comments for TBC1D10A

TBC1D10A: a GTPase-activating protein (GAP) for RAB27A, but not for RAB2A, RAB3A, nor RAB4A. Binds to the first PDZ domain of SLC9A3R1 and SLC9A3R2. Localizes to the microvilli-rich region of the syncytiotrophoblast. In melanocytes, located at the periphery of cells.

Protein type: GAPs, Rab; GAPs

Chromosomal Location of Human Ortholog: 22q12.2

Cellular Component: microvillus; plasma membrane

Molecular Function: protein binding; guanyl-nucleotide exchange factor activity; PDZ domain binding

Biological Process: positive regulation of proteolysis; retrograde transport, endosome to Golgi
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Research Articles on TBC1D10A

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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